Displaying drugs 8601 - 8625 of 11439 in total
Ropidoxuridine
Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated a survival advantage in Phase II studies in anaplastic astrocytoma, a type of brain tumor.
Investigational
Matched Synonyms: … 5-iodo-2-pyrimidinone-2'-deoxyribose ... 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-IODOPYRIMIDIN-2(1H)-ONE ... 2(1H)-PYRIMIDINONE, 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-IODO- …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one …
Carbon black
Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment with demonstrated adverse effects on pulmonary function. Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue and has been linked to carcinogenicity.[A263406, A263411, A263416]
Investigational
Matched Synonyms: … BLACK 2 ... D&C black no. 2 ... DC BLACK NO. 2 …
Eflepedocokin alfa
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Description: … recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 …
Skin-derived ABCB5-positive Mesenchymal Stem cells
Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 (Allogeneic Abcb5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase Iib)).
Investigational
2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID
Experimental
Matched Iupac: … 2-{[7-(carboxymethoxy)-9-(hydroxyimino)-9H-fluoren-2-yl]oxy}acetic acid …
(RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE
Experimental
Matched Name: … (RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE …
Matched Iupac: … (R)-((2R)-1-phenoxybutan-2-yl methylphosphonochloridate) …
Matched Iupac: … (R)-((2R)-1-phenoxybutan-2-yl methylphosphonochloridate) …
6-[2-(1H-INDOL-6-YL)ETHYL]PYRIDIN-2-AMINE
Experimental
Matched Name: … 6-[2-(1H-INDOL-6-YL)ETHYL]PYRIDIN-2-AMINE …
Matched Iupac: … 6-[2-(1H-indol-6-yl)ethyl]pyridin-2-amine …
Matched Iupac: … 6-[2-(1H-indol-6-yl)ethyl]pyridin-2-amine …
BNT162c2 SARS-CoV-2 Vaccine
BNT162c2 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162c2 is a self-amplifying mRNA (saRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.[L15002, L15007]
BNT162c2 is undergoing evaluation in clinical trials in both the USA (NCT04368728)...
Investigational
Matched Name: … BNT162c2 SARS-CoV-2 Vaccine …
Exebacase
Exebacase is under investigation in clinical trial NCT03163446 (Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia).
Investigational
Etigilimab
Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Investigational
3-Indolebutyric Acid
Experimental
Matched Name: … 3-Indolebutyric Acid …
Matched Iupac: … 4-(1H-indol-3-yl)butanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 4-(1H-indol-3-yl)butanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
3-Iodo-Benzyl Alcohol
Experimental
Matched Name: … 3-Iodo-Benzyl Alcohol …
Matched Iupac: … (3-iodophenyl)methanol …
Matched Iupac: … (3-iodophenyl)methanol …
Poloxamer 237
Experimental
Octyldodecanol
Experimental
Matched Synonyms: … 2-Octyl dodecanol ... 2-Octyl-1-dodecanol ... 2-Octyldodecyl alcohol …
Matched Iupac: … 2-octyldodecan-1-ol …
Matched Iupac: … 2-octyldodecan-1-ol …
Sotigalimab
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
2-Hydroxyquinoline
Experimental
Matched Synonyms: … 2-quinolone ... Quinolin-2-ol ... 2(1H)-Quinolinone …
Matched Name: … 2-Hydroxyquinoline …
Matched Iupac: … 1,2-dihydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Name: … 2-Hydroxyquinoline …
Matched Iupac: … 1,2-dihydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
N-(2-Aminoethyl)-1-aziridineethanamine
First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Experimental
Matched Synonyms: … N-(2-((2-Aminoethyl)amino)ethyl)aziridine ... N-(2-aminoethyl)-1 aziridine-ethanamine …
Matched Name: … N-(2-Aminoethyl)-1-aziridineethanamine …
Matched Iupac: … (2-aminoethyl)[2-(aziridin-1-yl)ethyl]amine …
Matched Description: … First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental ... angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease …
Matched Name: … N-(2-Aminoethyl)-1-aziridineethanamine …
Matched Iupac: … (2-aminoethyl)[2-(aziridin-1-yl)ethyl]amine …
Matched Description: … First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental ... angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease …
Zalypsis
Zalypsis has been used in trials studying the treatment of Lymphoma, Solid Tumors, Ewing's Sarcoma, Endometrial Cancer, and Uterine Cervical Cancer, among others.
Investigational
Matched Iupac: … -4(12),5,7(11),18(23),19,21-hexaen-5-yl acetate ... (1R,2S,13R,15S,16S)-15,22-dihydroxy-21-methoxy-6,20,24-trimethyl-13-{[(2E)-3-[3-(trifluoromethyl)phenyl ... ]prop-2-enamido]methyl}-8,10-dioxa-14,24-diazahexacyclo[14.7.1.0^{2,14}.0^{4,12}.0^{7,11}.0^{18,23}]tetracosa …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
N-acetyl-alpha-D-glucosamine
The N-acetyl derivative of glucosamine.
Experimental
Matched Synonyms: … 2-(acetylamino)-2-deoxy-A-D-glucopyranose ... 2-(acetylamino)-2-deoxy-α-D-glucopyranose …
Matched Iupac: … N-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide …
Matched Iupac: … N-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide …
Denenicokin
Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
N-T-Butylhydroxylamine
Investigational
Matched Synonyms: … 2-hydroxylamino-2-methylpropane ... N-hydroxy-2-methyl-2-propanamine …
Darleukin
Investigational
L-deprenyl-D2 C-11
L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).
Investigational
Matched Iupac: … (11C)methyl[(2R)-1-phenylpropan-2-yl][(1,1-2H2)prop-2-yn-1-yl]amine …
Parasorbic acid
Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe berries of the mountain ash.
Experimental
Matched Synonyms: … 2-Hexen-5,1-olide ... 5-Hydroxy-2-hexenoic acid lactone ... (S)-(+)-5,6-Dihydro-6-methyl-2H-pyran-2-one …
Matched Iupac: … (6S)-6-methyl-5,6-dihydro-2H-pyran-2-one …
Matched Iupac: … (6S)-6-methyl-5,6-dihydro-2H-pyran-2-one …
(R)-Mandelic acid
Experimental
Matched Synonyms: … (2R)-2-hydroxy-2-phenylacetic acid ... (R)-2-Hydroxy-2-phenylacetic acid ... D-2-phenylglycolic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Displaying drugs 8601 - 8625 of 11439 in total