Displaying drugs 8651 - 8675 of 11669 in total
Oglufanide
Oglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis C viral infection. Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before being acquired by...
Investigational
Matched Iupac: … (4S)-4-amino-4-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}butanoic acid …
(1R,2R)-N-(2-Aminoethyl)-2-{[(4-methoxyphenyl)sulfonyl]methyl}cyclohexanecarboxamide
Experimental
Matched Name: … (1R,2R)-N-(2-Aminoethyl)-2-{[(4-methoxyphenyl)sulfonyl]methyl}cyclohexanecarboxamide …
Matched Iupac: … (1R,2R)-N-(2-aminoethyl)-2-[(4-methoxybenzenesulfonyl)methyl]cyclohexane-1-carboxamide …
Matched Iupac: … (1R,2R)-N-(2-aminoethyl)-2-[(4-methoxybenzenesulfonyl)methyl]cyclohexane-1-carboxamide …
MK-1454
A synthetic cyclic dinucleotide (CDN) and agonist of stimulator of interferon genes protein (STING), with potential immunoactivating and antineoplastic activities. Upon intratumoral (IT) administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB)...
Investigational
Matched Description: … kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB) and interferon regulatory factor 3 …
2-Aminophenol
Experimental
Matched Synonyms: … 2-Aminophenol …
Matched Name: … 2-Aminophenol …
Matched Iupac: … 2-aminophenol …
Matched Name: … 2-Aminophenol …
Matched Iupac: … 2-aminophenol …
2-Allylphenol
Experimental
Matched Name: … 2-Allylphenol …
Matched Iupac: … 2-(prop-2-en-1-yl)phenol …
Matched Iupac: … 2-(prop-2-en-1-yl)phenol …
XP21279
XP21279 is a prodrug of Levodopa, a dopamine precursor used in the management of Parkinson's disease. XP21279 was under investigation in clinical trial NCT00914602 (An Exploratory Study of XP21279 (With Lodosyn®) and Sinemet® in Parkinson's Disease Subjects), administered in combination with Carbidopa.
Investigational
1,2-Hexanediol
Experimental
(S)-camphor
(S)-camphor, or L(-)-Camphor, is a stereoisomer of DB01744, a bicyclic monoterpene known to potentiate both heat and cold sensations . (S)-camphor is not the naturally-occurring stereoisomer but displays similar TRPV channel affinity and current inhibition . DB01744 is isolated from the wood of the camphor laurel tree, Cinnamomum camphora, and...
Experimental
Matched Synonyms: … (−)-bornan-2-one …
Matched Iupac: … (1S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Iupac: … (1S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
Experimental
Matched Synonyms: … 7-(α-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one ... 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Name: … 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Iupac: … 4-methyl-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …
Matched Name: … 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Iupac: … 4-methyl-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …
5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID
Experimental
Matched Name: … 5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID …
Matched Iupac: … 5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid …
Matched Iupac: … 5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid …
2,6-dibromo-4-[(E)-2-phenylethenyl]phenol
Experimental
Matched Name: … 2,6-dibromo-4-[(E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dibromo-4-[(1E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dibromo-4-[(1E)-2-phenylethenyl]phenol …
Seletracetam
Seletracetam is a pyrrolidone derivative and with a structural similarity to newer generation antiepileptic drug levetiracetam. It binds to the same target as levetiracetam but with higher affinity and has shown potent seizure suppression in models of acquired and genetic epilepsy with high CNS tolerability. It is predicted to have...
Investigational
Matched Synonyms: … (2S)-2-((4S)-4-(2,2-Difluoroethenyl)-2-oxopyrrolidin-1-yl)butanamide …
Matched Iupac: … (2S)-2-[(4S)-4-(2,2-difluoroethenyl)-2-oxopyrrolidin-1-yl]butanamide …
Matched Iupac: … (2S)-2-[(4S)-4-(2,2-difluoroethenyl)-2-oxopyrrolidin-1-yl]butanamide …
Poloxamer 237
Experimental
6-[2-(1H-INDOL-6-YL)ETHYL]PYRIDIN-2-AMINE
Experimental
Matched Name: … 6-[2-(1H-INDOL-6-YL)ETHYL]PYRIDIN-2-AMINE …
Matched Iupac: … 6-[2-(1H-indol-6-yl)ethyl]pyridin-2-amine …
Matched Iupac: … 6-[2-(1H-indol-6-yl)ethyl]pyridin-2-amine …
BNT162c2 SARS-CoV-2 Vaccine
BNT162c2 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162c2 is a self-amplifying mRNA (saRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.[L15002, L15007]
BNT162c2 is undergoing evaluation in clinical trials in both the USA (NCT04368728)...
Investigational
Matched Name: … BNT162c2 SARS-CoV-2 Vaccine …
2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID
Experimental
Matched Iupac: … 2-{[7-(carboxymethoxy)-9-(hydroxyimino)-9H-fluoren-2-yl]oxy}acetic acid …
(RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE
Experimental
Matched Name: … (RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE …
Matched Iupac: … (R)-((2R)-1-phenoxybutan-2-yl methylphosphonochloridate) …
Matched Iupac: … (R)-((2R)-1-phenoxybutan-2-yl methylphosphonochloridate) …
2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
Experimental
Matched Name: … 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID …
Matched Iupac: … 2-(2,4-dichlorobenzamido)-5-(pyrimidin-2-yloxy)benzoic acid …
Matched Iupac: … 2-(2,4-dichlorobenzamido)-5-(pyrimidin-2-yloxy)benzoic acid …
2-(Pyrido[1,2-E]Purin-4-Yl)Amino-Ethanol
Experimental
Matched Name: … 2-(Pyrido[1,2-E]Purin-4-Yl)Amino-Ethanol …
Matched Iupac: … 2-({pyrido[2,1-h]purin-4-yl}amino)ethan-1-ol …
Matched Iupac: … 2-({pyrido[2,1-h]purin-4-yl}amino)ethan-1-ol …
Tariquidar
Investigational
Matched Iupac: … ]quinoline-3-carboxamide ... N-[2-({4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]phenyl}carbamoyl)-4,5-dimethoxyphenyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tonabersat
Investigational
Matched Iupac: … N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
BQ-123
BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
Investigational
Matched Iupac: … 2-[(3R,6S,9R,12R,17aS)-9-[(1H-indol-3-yl)methyl]-6-(2-methylpropyl)-1,4,7,10,13-pentaoxo-3-(propan-2- …
Incadronic acid
Incadronate, or YM-175, is a nitrogen containing bisphosphonate. Along with being investigated to treat hypercalcemia of malignancy, it has also been investigated in the treatment of myeloma, leukemia, and other cancers.[A14426,A14431,A14427,A202769]
Incadronic acid was first described in the literature in 1991.
Experimental
CP-122721
CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.
Investigational
Matched Iupac: … (2S,3S)-N-{[2-methoxy-5-(trifluoromethoxy)phenyl]methyl}-2-phenylpiperidin-3-amine …
(R)-4-Nitrostyrene oxide
Experimental
Matched Synonyms: … (2R)-2-(4-nitrophenyl)oxirane …
Matched Iupac: … (2R)-2-(4-nitrophenyl)oxirane …
Matched Iupac: … (2R)-2-(4-nitrophenyl)oxirane …
Displaying drugs 8651 - 8675 of 11669 in total