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Displaying drugs 8651 - 8675 of 10838 in total
Investigational
AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Used for treating vestibular-related imbalance and vertigo.
Experimental
Matched Synonyms: … (R,S)-N-Acetylleucin …
Matched Iupac: … 2-acetamido-4-methylpentanoic acid …
Experimental
Matched Synonyms: … (S)-2-Amino-3-(naphthalen-1-yl)propanoic acid …
Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).
Investigational
Matched Iupac: … (2S)-2-amino-4-(ethylcarbamoyl)butanoic acid …
Experimental
Vet approved
Matched Iupac: … 4-(dimethylamino)-2,2-diphenylpentanamide …
The use of umbilical cord blood (UCB) for therapies is advantageous because of its ease of access, non-invasive collection procedures, and more plasticity for multi-differentiation. UCB contains a large source of hematopoietic stem cells (HSCs) that are capable of self-renewal, have increased sensitivity to various factors, and are able to...
Investigational
Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone.
Experimental
Matched Iupac: … 2-{[4-(4-aminobenzenesulfonyl)phenyl]amino}acetic acid …
Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostaglandins have a wide variety of actions, including,...
Investigational
Matched Description: … Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. …
Experimental
Matched Iupac: … 4-(dipropylcarbamoyl)-4-(phenylformamido)butanoate ... 3-{4-[2-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)ethyl]piperazin-1-yl}propyl …
Melaleuca alternifolia leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Iupac: … N-{3-[(3S,6S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,42S,45S)-3,30-bis(4-aminobutyl)-24,36-bis[(2S)-butan ... -4-yl)methyl]-15-[(1H-indol-3-yl)methyl]-21-(2-methylpropyl)-2,5,11,14,17,20,23,26,29,32,35,38,41,44- ... -2-yl]-18-(3-carbamimidamidopropyl)-33,42-bis(hydroxymethyl)-27-[(4-hydroxyphenyl)methyl]-39-[(1H-imidazol …
Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.
Investigational
Experimental
Matched Synonyms: … (S)-phenylalanine methyl ester …
Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational
Investigational
Matched Iupac: … (2S)-3-(2-sulfanylidene-2,3-dihydro-1H-imidazol-4-yl)-2-(trimethylazaniumyl)propanoate …
Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational
Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.
Investigational
Experimental
Investigational
Displaying drugs 8651 - 8675 of 10838 in total