Displaying drugs 851 - 875 of 1153 in total
ALT-P1
ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Recombinant human growth hormone fused to alpha1-antitrypsin variant …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Sotigalimab
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS ... CUNICULUS MONOCLONAL APX005M .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-ORYCTOLAGUS CUNICULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Exlinkibart
Investigational
Matched Synonyms: … factor receptor TNFRSF9) (human-mus musculus monoclonal lvgn6051 .hamma.1-chain), disulfide with human-mus ... Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis …
Lutikizumab
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Resamirigene bilparvovec
AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying) ... Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin gene …
Exbivirumab
Exbivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Matched Synonyms: … with human monoclonal 19.79.5 .lambda. chain, dimer ... Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 19.79.5 heavy chain), disulfide …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Libivirumab
Libivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Matched Synonyms: … with human monoclonal 17.1.41 .kappa. ... Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 17.1.41 heavy chain), disulfide …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Canoctakin
Investigational
Matched Synonyms: … -tetra-l-lysine)human interleukin 8 precursor-(34-99)- peptide anti-inflammatory ... Interleukin 8 (synthetic human clone dncxcl8 increased-glycosaminoglycan binding isoform pa401) ... Recombinant dna derived, human interleukin 8 (cxcl8) mutein, produced in escherichia coli: (44,48,97,98 …
Mecbotamab vedotin
Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (DE-450-LYSINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL ... BA301 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL BA301 .KAPPA. …
PAT-SM6
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Respigam
Investigational
Matched Synonyms: … Respiratory syncytial virus immune globulin intravenous (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
CT-001
Investigational
Matched Synonyms: … Human recombinant factor VIIa variant (P10Q, K32E, T106N, V253N), desialylated …
Angiotensin II
Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.
As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … Human angiotensin II ... Angiotensin II (human) …
Matched Description: … Shock is the inability to maintain blood flow to vital tissues and the potential resultant organ failure ... The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... and death within hours, no matter young or o ld. …
Matched Categories: … Nerve Tissue Proteins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Shock is the inability to maintain blood flow to vital tissues and the potential resultant organ failure ... The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... and death within hours, no matter young or o ld. …
Matched Categories: … Nerve Tissue Proteins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Avalotcagene ontaparvovec
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 encoding human ornithine transcarbamylase ... Recombinant adeno-associated virus serotype AAV8 vector encoding human ornithine transcarbamylase …
Ciliary neurotrophic factor
NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete ciliary neurotrophic factor (CNTF). It is under investigation for the treatment of retinitis pigmentosa and age-related macular degeneration.
Investigational
Matched Synonyms: … HUMAN CNTF ... HUMAN CILIARY NEUROTROPHIC FACTOR ... CILIARY NEUROTROPHIC FACTOR (HUMAN) …
Matched Description: … [L46762] It is under investigation for the treatment of retinitis pigmentosa and age-related macular ... NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete …
Matched Categories: … Nerve Tissue Proteins ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … [L46762] It is under investigation for the treatment of retinitis pigmentosa and age-related macular ... NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete …
Matched Categories: … Nerve Tissue Proteins ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Valziflocept
Investigational
Matched Synonyms: … Recombinant human soluble fc-gamma receptor iib ... Fc.gamma.riib receptor (human soluble extracellular fragment) ... Human immunoglobulin gamma fc region receptor ii-b (fc.gamma.rii-b), extracellular n-terminal fragment …
Perenostobart
Perenostobart is an alpha-CD39 IgG4 monoclonal antibody.
Investigational
Matched Synonyms: … Immunoglobulin G4 [229-proline], anti-(human ectonucleoside triphosphate diphosphohydrolase 1) (human ... monoclonal SRF617 γ4-chain), disulfide with human monoclonal SRF617 κ-chain, dimer …
Gatipotuzumab
Gatipotuzumab is under investigation in clinical trial NCT01899599 (Pankomab-gex™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer).
Investigational
Matched Synonyms: … with human-mus musculus monoclonal pankomab-gex light chain, dimer ... Immunoglobulin g1, anti-(mucin muc1) (human-mus musculus monoclonal pankomab-gex heavy chain), disulfide …
Pucotenlimab
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus ... musculus monoclonal hx008 .gamma.4-chain), disulfide with human-mus musculus monoclonal hx008 .kappa …
Ragifilimab
Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1 (de-448-lysine), anti-(human tumor necrosis factor receptor tnfrsf18) (human-mus musculus ... monoclonal incagn01876.gamma.1-chain), disulfide with human-mus musculus monoclonal incagn01876 .kappa …
Neoarsphenamine
Investigational
Withdrawn
Matched Synonyms: … Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium salt …
Nemvaleukin alfa
Investigational
Matched Synonyms: … -chain (human) ... 2 receptor α-chain (human) ... human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human …
CAN-106
CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5.
Investigational
Matched Synonyms: … disulfide with human monoclonal CAN106 Kappa-chain, dimer ... Immunoglobulin G [27-histidine,57-histidine,253-tyrosine,255- threonine,257-glutamic acid], anti-(human ... complement C5) (human monoclonal CAN106 hybrid y2-chain CH1-hinge region/y4-chain CH2- CH3 region), …
Matched Description: … CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5. …
Matched Description: … CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5. …
Empegfilgrastim
Empegfilgrastim is under investigation in clinical trial NCT01569087 (Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer).
Investigational
Matched Synonyms: … Colony-stimulating factor, granulocyte (synthetic human), 30-kilodalton pegylated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Displaying drugs 851 - 875 of 1153 in total