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Displaying drugs 8726 - 8750 of 11803 in total

WVE-003

WVE-003 is an allele-selective antisense oligonucleotide that works to selectively reduce the toxic mutant huntingtin (mHTT) protein.
Investigational

Calcium cation

Experimental
Matched Synonyms: … Calcium (2+) ... calcium(2+) ion ... Calcium(2+)ions …
Matched Iupac: … calcium(2+) ion …

9CUAB30

9 Cuab30 has been used in trials studying the treatment and prevention of HER2/Neu Positive, HER2/Neu Negative, No Evidence of Disease, Estrogen Receptor Negative, and estrogen receptor positive, among others.
Investigational
Matched Iupac: … (2E,4E,6Z)-3,7-dimethyl-8-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidene]octa-2,4,6-trienoic acid …

N-[1-(2,6-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide

Experimental
Matched Name: … N-[1-(2,6-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide …
Matched Iupac: … N-{1-[(2,6-dimethoxyphenyl)methyl]piperidin-4-yl}-4-sulfanylbutanamide …

(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE

Experimental
Matched Name: … (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE …
Matched Iupac: … 4-methyl-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …

6-bromopurine

Experimental

Interleukin-15, human recombinant

Investigational

Rugonersen

Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of Angelman Syndrome.
Investigational

Rebisufligene etisparvovec

Investigational

Compound 19

Experimental
Matched Iupac: … (2S,3R)-3-(4-hydroxyphenyl)-2-{4-[(2R)-2-(pyrrolidin-1-yl)propoxy]phenyl}-2,3-dihydro-1,4-benzoxathiin …

NU1025

Experimental
Matched Iupac: … 8-hydroxy-2-methyl-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Compound 18

Experimental
Matched Iupac: … (2S,3R)-3-(4-hydroxyphenyl)-2-{4-[(2S)-2-(pyrrolidin-1-yl)propoxy]phenyl}-2,3-dihydro-1,4-benzoxathiin …

AT1022

AT1022 is a hydromorphone skin patch designed to provide rapid and sustained delivery of a potent opiate for the management of severe pain. AT1022 incorporates PassPort(TM) system, developed to deliver protein and peptide drugs, small-molecule drugs, genes and vaccines across the skin for local and systemic effect.
Investigational

ND1251

ND1251 is an orally active phosphodiesterase-4 (PDE4) inhibitor, a mechanism clinically proven to play a role in alleviating symptoms of depression. ND1251 is a very potent compound with a large safety margin. ND1251 may also have applications in other disorders, such as Alzheimer's disease, mild cognitive impairment, multiple sclerosis and...
Investigational

OMS-103HP

OMS103HP is the first drug being developed to improve joint function following arthroscopic surgery, one of the most common procedures performed today by orthopedic surgeons.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

DOTMP HO-166

DOTMP HO-166 is used in skeletal targeted radiotherapy (STR). SRT is designed to be used in combination with high-dose chemotherapy producing a direct therapeutic effect on the tumor sites in the bone plus a general bone-marrow effect to destroy myeloma cells in the bone marrow. It is an experimental therapy...
Investigational
Matched Iupac: … lambda2-(166Ho)holmium(2+) ion {[4,7,10-tris(phosphonomethyl)-1,4,7,10-tetraazacyclododecan-1-yl]methyl …

GSK-1292263

GSK1292263 has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.
Investigational
Matched Iupac: … 2-(4-methanesulfonylphenyl)-5-({1-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-4-yl}methoxy)pyridine …
Matched Description: … GSK1292263 has been investigated for the treatment of DIABETES MELLITUS, TYPE 2. …

Iodine I-125

Iodine I-125 is under investigation in clinical trial NCT00079417 (Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma).
Investigational

ISIS 104838

ISIS 104838 is under investigation in clinical trial NCT00048321 (ISIS 104838, an Inhibitor of Tumor Necrosis Factor, for Active Rheumatoid Arthritis).
Investigational

QL1706

QL1706 is an investigational bifunctional antibody that combines the activity of both PD-1 and CTLA-4 antibodies.
Investigational
Matched Description: … QL1706 is an investigational bifunctional antibody that combines the activity of both PD-1 and CTLA-4 …

SNSP113

Investigational

BIIB115

BIIB115 is an investigational antisense oligonucleotide in development for spinal muscular atrophy.
Investigational

ATIR101

ATIR101 is a haploidentical, naïve cell-enriched T-cell therapy.
Investigational

MS1901

Investigational

Oglufanide

Oglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis C viral infection. Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before being acquired by...
Investigational
Matched Iupac: … (4S)-4-amino-4-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}butanoic acid …
Displaying drugs 8726 - 8750 of 11803 in total