Displaying drugs 8726 - 8750 of 10863 in total
CTx-PDE6b
CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human PDE6b gene. Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to PDE6b gene mutations.
Investigational
Taminadenant
Investigational
Oxfendazole
Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Investigational
Vet approved
Matched Synonyms: … 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazole ... 5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester ... (5-(phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[5-(benzenesulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … methyl N-[5-(benzenesulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide
Experimental
Matched Iupac: … (2R,4S)-N-hydroxy-4-(methoxyamino)-1-(4-methoxybenzenesulfonyl)pyrrolidine-2-carboxamide …
5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide
Experimental
Matched Name: … 5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide …
Matched Iupac: … 5-chloro-N-[(2R)-2-[cyclopentyl(2-hydroxyethyl)amino]-2-hydroxyethyl]-1H-indole-2-carboxamide …
Matched Iupac: … 5-chloro-N-[(2R)-2-[cyclopentyl(2-hydroxyethyl)amino]-2-hydroxyethyl]-1H-indole-2-carboxamide …
4-Methyl-N-[5-(5-methyl-furan-2-ylmethylene)-4-oxo-thiazolidin-2-ylidene]-benzenesulfonamide
Experimental
Matched Name: … 4-Methyl-N-[5-(5-methyl-furan-2-ylmethylene)-4-oxo-thiazolidin-2-ylidene]-benzenesulfonamide …
Matched Iupac: … 4-methyl-N-[(5Z)-5-[(5-methylfuran-2-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]benzene-1-sulfonamide …
Matched Iupac: … 4-methyl-N-[(5Z)-5-[(5-methylfuran-2-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]benzene-1-sulfonamide …
N-Pyridoxyl-2-Methylalanine-5-Phosphate
Experimental
Matched Name: … N-Pyridoxyl-2-Methylalanine-5-Phosphate …
Matched Iupac: … 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpropanoic acid …
Matched Iupac: … 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpropanoic acid …
2-phenyl-1H-imidazole-4-carboxylic acid
Experimental
Matched Name: … 2-phenyl-1H-imidazole-4-carboxylic acid …
Matched Iupac: … 2-phenyl-1H-imidazole-4-carboxylic acid …
Matched Iupac: … 2-phenyl-1H-imidazole-4-carboxylic acid …
2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE
Experimental
Matched Name: … 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE …
Matched Iupac: … 1-[4-methyl-2-(phenylamino)-1,3-thiazol-5-yl]ethan-1-one …
Matched Iupac: … 1-[4-methyl-2-(phenylamino)-1,3-thiazol-5-yl]ethan-1-one …
Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)
The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853]. In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce a functional antibody response within 7-14 days of initial injection . It...
Investigational
Matched Name: … Recombinant SARS-CoV-2 Vaccine (Sf9 Cell) …
Matched Description: … The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding ... It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. …
Matched Description: … The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding ... It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. …
Saruplase
Experimental
Vodudeutentan
Investigational
Matched Iupac: … ]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid ... (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-di(2H1)methylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
6-hydroxymethylpterin diphosphate
Experimental
Matched Synonyms: … 2-Amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphate …
Matched Iupac: … ({[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … ({[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
BBV152
BBV152 is a vaccine candidate created by the Indian Council of Medical Research (ICMR). The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or a novel TLR7/8 agonist adsorbed gel....
Investigational
Matched Synonyms: … Whole-Virion Inactivated SARS-CoV-2 Vaccine …
Matched Description: … The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV ... -2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or ... Thus, as of July 2020, BBV152 is in Phase 1/2 clinical trials assessing safety and immunogenicity in …
Matched Description: … The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV ... -2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or ... Thus, as of July 2020, BBV152 is in Phase 1/2 clinical trials assessing safety and immunogenicity in …
Bemarituzumab
Bemarituzumab is under investigation in clinical trial NCT03694522 (A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (Mfolfox6) in Gastric/gastroesophageal Junction Cancer (FIGHT)).
Investigational
1-Hydroxyamine-2-Isobutylmalonic Acid
Experimental
Matched Name: … 1-Hydroxyamine-2-Isobutylmalonic Acid …
Matched Iupac: … (2R)-2-(hydroxycarbamoyl)-4-methylpentanoic acid …
Matched Iupac: … (2R)-2-(hydroxycarbamoyl)-4-methylpentanoic acid …
S-(2-Acetamidoethyl) hexadecanethioate
Experimental
Matched Name: … S-(2-Acetamidoethyl) hexadecanethioate …
Matched Iupac: … N-[2-(hexadecanoylsulfanyl)ethyl]acetamide …
Matched Iupac: … N-[2-(hexadecanoylsulfanyl)ethyl]acetamide …
2'-O-Acetyl Adenosine-5-Diphosphoribose
Experimental
Matched Name: … 2'-O-Acetyl Adenosine-5-Diphosphoribose …
Matched Iupac: … ,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid ... [({[(2R,3R,4R,5S)-4-(acetyloxy)-3,5-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R …
Matched Iupac: … ,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid ... [({[(2R,3R,4R,5S)-4-(acetyloxy)-3,5-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R …
2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID
Experimental
Matched Name: … 2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID …
Matched Iupac: … 2',6'-difluoro-[1,1'-biphenyl]-4-carboxylic acid …
Matched Iupac: … 2',6'-difluoro-[1,1'-biphenyl]-4-carboxylic acid …
5-fluoro-2'-deoxyuridine-5'-monophosphate
Experimental
Matched Name: … 5-fluoro-2'-deoxyuridine-5'-monophosphate …
Matched Iupac: … {[(2R,3S,5R)-5-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … {[(2R,3S,5R)-5-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE
Experimental
Matched Name: … 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE …
Matched Iupac: … 4-phenoxy-N-[(pyridin-2-yl)methyl]benzamide …
Matched Iupac: … 4-phenoxy-N-[(pyridin-2-yl)methyl]benzamide …
N-oxo-2-(phenylsulfonylamino)ethanamide
Experimental
Matched Name: … N-oxo-2-(phenylsulfonylamino)ethanamide …
Matched Iupac: … 2-benzenesulfonamido-N-oxoacetamide …
Matched Iupac: … 2-benzenesulfonamido-N-oxoacetamide …
Flubendazole
Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Experimental
Withdrawn
Matched Synonyms: … methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate ... (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[5-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … FLUOBEN® SUSPENSION 2% …
Matched Iupac: … methyl N-[5-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … FLUOBEN® SUSPENSION 2% …
Zorevunersen
Investigational
Matched Synonyms: … Rna, (p-thio)(2'-o-(2-methoxyethyl))(a-g-m5u-m5u-g-g-a-g-m5c-a-a-g-a-m5u-m5u-a-m5u-m5c) …
A-620223
Experimental
Matched Synonyms: … trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium …
Matched Iupac: … 2-(1-propylpiperidin-4-yl)-1H-1,3-benzodiazole-7-carboxamide …
Matched Iupac: … 2-(1-propylpiperidin-4-yl)-1H-1,3-benzodiazole-7-carboxamide …
Displaying drugs 8726 - 8750 of 10863 in total