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Displaying drugs 8776 - 8800 of 11668 in total

ISA101b

ISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins.
Investigational

CHROMOPHORE (ASP-TYR-GLY)

Experimental
Matched Iupac: … (3S)-3-amino-3-[(4Z)-1-(carboxymethyl)-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol …

NCX 701

Nitroparacetamol (NCX-701) is a newly synthesized nitric oxide-releasing derivative of paracetamol.
Investigational
Matched Iupac: … 4-acetamidophenyl 4-(nitrooxy)butanoate …

Meclinertant

Investigational
Matched Iupac: … 2-[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-amido]adamantane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE

Experimental
Matched Iupac: … (2S)-2-amino-3-{2,4-dihydroxy-5-[(E)-(2-phenylethylidene)amino]phenyl}propanoic acid …

17-METHYL-17-ALPHA-DIHYDROEQUILENIN

Experimental

Interleukin-1 alpha, human recombinant

Experimental
Matched Synonyms: … IL-1 alpha ... Hematopoietin-1 ... Interleukin 1 alpha …
Matched Name: … Interleukin-1 alpha, human recombinant …
Matched Categories: … Interleukin-1 …

Izuralimab

Izuralimab is under investigation in clinical trial NCT05879185 (A Study of Xmab23104 in People With Sarcoma).
Investigational
Matched Synonyms: … PD-1, PD1, CD279)), M ... VARIABLE FRAGMENT VL-LINKER-VH) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C-REGION ... LYMPHOCYTE IMMUNOMEDIATORY MOLECULE, AILIM, CD278)) AND ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, …

Epothilone D

Investigational
Matched Iupac: … (4S,7R,8S,9S,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)prop ... -1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione …

SC12267

SC12267 is a novel, small molecule agent from the class of DMARDs (disease modifying anti-rheumatic drug) for the therapy of autoimmune diseases such as rheumatoid arthritis or multiple sclerosis. Through highly selective inhibition of pyrimidine biosynthesis, it controls the growth of rapidly proliferating cells, especially of lymphocytes, which are important...
Investigational

Atl146e

ATL146e is an anti-inflammatory compounds which is an agonist of A2A adenosine receptors.
Investigational

NUC B1000

NUC B1000 is an expressed interfering RNA (eiRNA)- based product consisting of a plasmid DNA construct designed to produce four short interfering RNA (siRNA) molecules, formulated with a proprietary cationic-lipid delivery system. eiRNA is an approach to RNAi therapeutics, whereby a plasmid DNA coding for desired dsRNA is delivered to...
Investigational
Matched Description: … On January 11, 2008, it was announced that NUC B1000 was entering a phase 1 human safety study of its …

GP-100 antigen

GP-100 antigen is under investigation in clinical trial NCT00006385 (Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma).
Investigational

SYNB1891

SYNB1891 is a live, modified strain of the probiotic Escherichia coli Nissle engineered to produce cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway. SYNB1891 is under investigation in clinical trial NCT04167137 (Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult...
Investigational

SYNB1020

SYNB1020 is an engineered strain of Escherichia coli Nissle 1917 developed by Synlogic Inc. It was initially designed to convert ammonia to L-arginine and granted orphan designation by the FDA for the treatment of urea cycle disorders in August 2016; however, the manufacturer discontinued further development of SYNB1020 to treat...
Investigational

HM15912

HM15912 is a human glucagon-like peptide-2 analogue linked to a human immunoglobulin Fc fragment.
Investigational

ZVS101e

ZVS101e is a recombinant adeno-associated virus vector carrying human CYP4V2 gene.
Investigational

SHR-A1904

SHR-A1904 is under investigation in clinical trial NCT04877717 (A Study of SHR-A1904 in Patients With Advanced Solid Cancer).
Investigational

rAAV1-CB-hAAT

rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector.
Investigational
Matched Synonyms: … recombinant adeno-associated virus alpha 1-antitrypsin vector …
Matched Description: … rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector. …

(1R,2S)-2-Phenylcyclopropanaminium

A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)
Experimental
Matched Synonyms: … (1R,2S)-tranylcypromine(1+) …
Matched Iupac: … (1R,2S)-2-phenylcyclopropan-1-aminium …

(1R)-menthyl hexyl phosphonate group

Experimental

BNT162a1 SARS-CoV-2 Vaccine

BNT162a1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162a1 is a uridine mRNA (uRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.[L15002, L15007] BNT162a1 is undergoing evaluation in clinical trials in both the USA (NCT04368728)...
Investigational

Ivarmacitinib

Ivarmacitinib (SHR0302) is a selective inhibitor of Janus kinase 1 (JAK1) under investigation for the treatment of various immuno-inflammatory conditions. While ivarmactinib has yet to receive marketing authorization, as of February 2022 clinical trials are ongoing or completed evaluating its use in atopic dermatitis,[L40604,L40619,L40629] ankylosing spondylitis, rheumatoid arthritis, psoriatic arthritis,...
Experimental
Investigational
Matched Iupac: … (3aR,5S,6aS)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]-octahydrocyclopenta …
Matched Description: … Ivarmacitinib (SHR0302) is a selective inhibitor of Janus kinase 1 (JAK1) under investigation for the …
Matched Salts cas: … 1639419-51-4 …
Matched Categories: … Janus Kinase 1, antagonists & inhibitors …

Lintuzumab satetraxetan AC-225

Lintuzumab actinium Ac-225 is under investigation in clinical trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies).
Investigational

CRA_23653

Experimental
Matched Iupac: … 2-[5-(6-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-6-hydroxy-[1,1'-biphenyl]-3-yl]ethan-1-aminium …
Displaying drugs 8776 - 8800 of 11668 in total