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Displaying drugs 8776 - 8800 of 11506 in total

Telotristat

A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
Experimental
Matched Iupac: … (2S)-2-amino-3-(4-{2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy ... ]pyrimidin-4-yl}phenyl)propanoic acid …

2',3'-Dideoxythymidine-5'-Monophosphate

Experimental
Matched Name: … 2',3'-Dideoxythymidine-5'-Monophosphate …
Matched Iupac: … {[(2S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …

8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-

Experimental
Matched Name: … 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- …
Matched Iupac: … 8-[(2H-1,3-benzodioxol-5-yl)methyl]-9-butyl-9H-purin-6-amine …

2-(5-fluoro-pentyl)-2-methyl-malonic-acid

2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).
Investigational
Matched Name: … 2-(5-fluoro-pentyl)-2-methyl-malonic-acid …
Matched Iupac: … 2-[5-(¹⁸F)fluoropentyl]-2-methylpropanedioic acid …
Matched Description: … 2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML …

Preimplantation factor

Preimplantation factor is under investigation in clinical trial NCT03593460 (Phase II Autoimmune Hepatitis).
Investigational
Matched Iupac: … amino-2-[(2S)-2-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-6-amino-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4- ... (methylsulfanyl)butanamido]-3-methylbutanamido]-5-carbamimidamidopentanamido]-3-methylpentanamido]hexanoyl …

D-Myo-Inositol-1,4-Bisphosphate

Experimental
Matched Iupac: … {[(1R,2R,3R,4R,5R,6S)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphonic acid …

N-sulfo-flavin mononucleotide

Experimental
Matched Iupac: … -5-ium-5-sulfonate ... 7,8-dimethyl-2,4-dioxo-10-[(2S,3S,4R)-2,3,4-trihydroxy-5-(phosphonooxy)pentyl]-2H,3H,4H,10H-benzo[g]pteridin …

Lixadesiran

Investigational

Phenylalanine-N-Sulfonamide

Experimental

Sambucus nigra flowering top

Experimental

Sonpiretigene isteparvovec

Sonpiretigene isteparvovec is an ambient-light activatable Multi-Characteristic Opsin (MCO) optogenetic therapy. Developed by Nanoscope Therapeutics, it is being investigated for vision restoration in advanced retinitis pigmentosa (RP). Sonpiretigene isteparvovec consists of a fusion Adeno-associated virus (AAV) vector with three plasmids encoding opsins with spectrally-separated activation peaks.
Investigational

Verbrinacogene setparvovec

Investigational

Boldenone

Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through veterinary clinics.
Illicit
Vet approved

3-(2-AMINO-6-BENZOYLQUINAZOLIN-3(4H)-YL)-N-CYCLOHEXYL-N-METHYLPROPANAMIDE

Experimental

alpha-Methylleucine

Experimental
Matched Synonyms: … (S)-2-Methylleucine …

S-Hydroxymethyl Glutathione

Experimental
Matched Name: … S-Hydroxymethyl Glutathione …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-[(hydroxymethyl)sulfanyl]ethyl]carbamoyl}butanoic …

N-oleoyldopamine

N-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid.
Investigational

Brodimoprim-4,6-Dicarboxylate

Brodimoprim-4,6-dicarboxylate is a solid. This compound belongs to the anisoles. These are organic compounds contaiing a methoxybenzene or a derivative thereof. This medication is known to target the protein dihydrofolate reductase.
Experimental
Matched Iupac: … 2,4-diamino-5-[(4-bromo-3-{[(4S)-4,6-dicarboxylatohexyl]oxy}-5-methoxyphenyl)methyl]pyrimidin-1-ium …

3H-pyrazolo[4,3-d]pyrimidin-7-ol

Experimental

A166

A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Synonyms: … Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5 …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) …

Levonadifloxacin

Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)).
Investigational
Matched Synonyms: … (s)-(-)-nadifloxacin ... Nadifloxacin, (s)- …
Matched Iupac: … (12S)-7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13 …

Bevifimod

Bevifimod is under investigation in clinical trial NCT01749787 (Safety Study of PRTX-100 With Methotrexate or Leflunomide to Treat Active Rheumatoid Arthritis).
Investigational

Theralizumab

Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]
Investigational

N-Pyridoxyl-2-Methylalanine-5-Phosphate

Experimental
Matched Name: … N-Pyridoxyl-2-Methylalanine-5-Phosphate …
Matched Iupac: … 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpropanoic acid …

5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE

Experimental
Matched Name: … 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE …
Matched Iupac: … -7-yl]oxy}-4-oxobutanoic acid ... 4-{[(1S,3aS,3bR,5aS,7S,9aS,9bS,11aS)-1-acetyl-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …
Displaying drugs 8776 - 8800 of 11506 in total