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Displaying drugs 8801 - 8825 of 11994 in total
Investigational
Experimental
Matched Name: … 2',6'-Dichloro-Biphenyl-2,6-Diol …
Matched Iupac: … 2',6'-dichloro-[1,1'-biphenyl]-2,3-diol …
Experimental
Matched Synonyms: … L-N2-(2-Carboxyethyl)arginine ... N2-(2-carboxyethyl)arginine ... N2-(2-Carboxyethyl)-L-arginine …
Matched Name: … N(2)-(2-carboxyethyl)-L-arginine …
Matched Iupac: … (2S)-5-carbamimidamido-2-[(2-carboxyethyl)amino]pentanoic acid …
Experimental
Matched Iupac: … [34.2.1.1^{2,5}.1^{12,15}.1^{19,22}.1^{26,29}.0^{6,11}]tritetraconta-1(38),2(43),4,6,8,10,12(42),14,19 ... (2S)-1-[(4S)-2-{2-[(18S,25S,35S)-35-[(S)-hydroxy(phenyl)methyl]-28-(methoxymethyl)-21-methyl-18-[(methylcarbamoyl ... (41),21,26(40),28,36(39)-tridecaen-8-yl]-1,3-thiazol-4-yl}-4,5-dihydro-1,3-oxazole-4-carbonyl]pyrrolidine ... -2-carboxamide ... )methyl]-16,23,30,33-tetraoxo-25-(propan-2-yl)-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decaazaheptacyclo …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 2-[5-(6-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-6-hydroxy-[1,1'-biphenyl]-3-yl]ethan-1-aminium …
AX200, which has been developed for the treatment of stroke, is the most advanced drug candidate and is halfway through the process of gaining clinical approval. The expression of the endogenous AX200 protein in the brain is increased after brain damage. Thus, if this drug administered in the acute phase...
Investigational
XL228 is a novel anticancer compound designed to inhibit the insulin-like growth factor type-1 receptor (IGF1R), Src and Abl tyrosine kinases – targets that play crucial roles in cancer cell proliferation, survival and metastasis.
Investigational
Matched Description: … XL228 is a novel anticancer compound designed to inhibit the insulin-like growth factor type-1 receptor …
XL281 is a novel anticancer compound designed to potently inhibit the RAS/RAF/MEK/ERK signaling pathway. Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer. XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which...
Investigational
At low doses, OPC 28326 selectively vasodilates the femoral arterial bed due to its inhibitory action at alpha-2-adrenoceptors while having minimal action on systemic blood pressure, heart rate and coronary, carotid, vertebral, renal, and mesenteric blood flows. It is the only clinical compound with this profile. It is currently being...
Investigational
Matched Iupac: … N-(2,6-dimethyl-4-{4-[methyl(2-phenylethyl)amino]piperidine-1-carbonyl}phenyl)propanamide hydrate hydrochloride …
Matched Description: … doses, OPC 28326 selectively vasodilates the femoral arterial bed due to its inhibitory action at alpha-2- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CTS-21166 is a small-molecule beta-secretase inhibitor, which is being developed as a disease-modifying treatment for Alzheimer's disease. CTS-21166 is the only BACE1 inhibitor that has passed Phase I clinical trial thus far. In 2008, CoMentis revealed this small compound as a transition-state analog inhibitor (structure is currently undisclosed) with excellent...
Investigational
Org 25435 has been used in trials studying the treatment of Anaesthesia.
Investigational
Matched Iupac: … 2,6-dimethoxy-4-methylphenyl (2R)-2-[bis(2-methoxyethyl)amino]butanoate …
PD-217,014 has been used in trials studying the treatment of Pain and Irritable Bowel Syndrome.
Investigational
Matched Iupac: … methyl 2-[(1R,3R,5S)-3-(aminomethyl)bicyclo[3.2.0]heptan-3-yl]acetate …
PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
Investigational
Matched Iupac: … N-[(1S)-1-(3-fluorophenyl)-3-[(1R,3S,5S)-3-[2-methyl-5-(2-methylpropanoyl)-1H,4H,5H,6H,7H-imidazo[4,5 ... -c]pyridin-1-yl]-8-azabicyclo[3.2.1]octan-8-yl]propyl]acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ro 24-7429 is under investigation in clinical trial NCT00002314 (A Study of Ro 24-7429 in Patients With Hiv-related Kaposi's Sarcoma).
Investigational
Matched Iupac: … 7-chloro-N-methyl-5-(1H-pyrrol-2-yl)-3H-1,4-benzodiazepin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Investigational
Matched Iupac: … [3,4-d]imidazol-4-yl]pentanamido}-2-{4-[(3S)-3-{[(2R)-3-(4-carbamimidoylphenyl)-1-oxo-1-(piperidin-1- ... yl)propan-2-yl]carbamoyl}-3-(4-methoxy-2,3,6-trimethylbenzenesulfonamido)propanamido]butanamido}hexanamido ... (2S,3S,4S,5R,6R)-3-{[(2R,3R,4S,5R,6R)-5-{2-[2-(2-{2-[(2S)-6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno ... -3-yl]oxy}-4,5-dimethoxyoxan-3-yl]oxy}-4,5-bis(sulfooxy)-2-[(sulfooxy)methyl]oxan-3-yl]oxy}-4,5-dimethoxyoxane ... -2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
PT217 is a bispecific Antibody against DLL3 and CD47
Investigational
Experimental
Illicit
Matched Name: … 4-Methylaminorex …
Matched Iupac: … 4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 4-Nitrophenyl-Ara …
Matched Iupac: … (2S,3R,4R,5S)-2-(hydroxymethyl)-5-(4-nitrophenoxy)oxolane-3,4-diol …
SAR421869 is a Lentiviral Vector Containing The Human My07A Gene currently being investigated for the treatment of retinitis pigmentosa associated with Usher syndrome 1B gene defect.
Investigational
Experimental
Matched Iupac: … (1R,4S)-3,3-dibromo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-({2-[(3-nitropropyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan- ... 3-yl]oxy}phosphonic acid …
Experimental
Matched Name: … 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE …
Matched Iupac: … 5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypyridine-2-carboxamide …
Experimental
Matched Name: … 5-Bromo-N[2-(Dimethylamino)Ethyl]-9-Aminoacridine-4-Carboxamide …
Matched Iupac: … 9-amino-4-bromo-5-{[2-(dimethylazaniumyl)ethyl]carbamoyl}acridin-10-ium …
Experimental
Matched Name: … 6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine …
Matched Iupac: … N-[4-(aminomethyl)phenyl]-6-carbamimidoylnaphthalene-2-carboxamide …
Displaying drugs 8801 - 8825 of 11994 in total