Displaying drugs 8901 - 8925 of 12089 in total
Malacidin B
Malacidin B, along with DB14051, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin B...
Experimental
Matched Iupac: … (3S)-3-{[(4S,7R,10S,13S,16S,22R,25S,29R,30aS)-10-(4-aminobutyl)-13-[carboxy(hydroxy)methyl]-22-(1-carboxyethyl ... yl]carbamoyl}-2-methyl-3-[(2E,4Z)-8-methyldeca-2,4-dienamido]propanoic acid ... nonaoxo-7,25-bis(propan-2-yl)-triacontahydropyrrolo[2,1-c]1,4,7,10,13,16,19,22,25-nonaazacyclooctacosan-4- …
Troclosene
Experimental
L-tartaric acid
Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.
Experimental
4-Carbamoyl-1-Beta-D-Ribofuranosyl-Imidazolium-5-Olate-5'-Phosphate
Experimental
Matched Name: … 4-Carbamoyl-1-Beta-D-Ribofuranosyl-Imidazolium-5-Olate-5'-Phosphate …
Matched Iupac: … 4-carbamoyl-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1H-imidazol …
Matched Iupac: … 4-carbamoyl-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1H-imidazol …
Tubercidin
An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
Experimental
Matched Iupac: … (2R,3R,4S,5R)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol …
1-Beta-Ribofuranosyl-1,3-Diazepinone
Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,3-dihydro-1H-1,3-diazepin-2-one …
6-Chloropurine Riboside, 5'-Monophosphate
Experimental
Matched Iupac: … 6-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-9H-purin-1-ium …
Bisegliptin
Bisegliptin is a compound for the treatment of type 2 diabetes. It is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion and lowering blood glucose levels without hypoglycemic effects.
Investigational
Matched Iupac: … ethyl 4-({2-[(2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl]-2-oxoethyl}amino)bicyclo[2.2.2]octane-1-carboxylate …
Torcetrapib
Torcetrapib (CP-529414, Pfizer) was developed to treat hypercholesterolemia but its development was halted in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination of atorvastatin and the study drug.
Investigational
Matched Iupac: … ethyl (2R,4S)-4-({[3,5-bis(trifluoromethyl)phenyl]methyl}(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl …
Ibacitabine
Experimental
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one …
2'-deoxythioguanosine
Investigational
Matched Iupac: … 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purine-6-thione …
RRx-001
RRx-001 has been used in trials studying the treatment of Lymphomas, Brain Metastases, Cholangiocarcinoma, Colorectal Neoplasms, and Malignant Solid Tumor, among others.
Investigational
LY3884961
LY3884961 (previously PR001) is being developed by Prevail Therapeutics as a single-dose gene therapy for patients with Parkinson's disease and Gaucher disease.
Investigational
Deacetoxyvinzolidine
Experimental
Matched Iupac: … methyl (13S,15R,17S)-13-[(1'R,2R,9'R,12'R,19'S)-4-(2-chloroethyl)-12'-ethyl-5'-methoxy-8'-methyl-3,5- ... ,6',13'-tetraen-4'-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12 ... -8',16'-diazaspiro[1,4-oxazolidine-2,10'-pentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadecane]-2',4' …
Balhimycin
Balhimycin is a novel glycopeptide antibiotic.
Experimental
Matched Iupac: … -19-[4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-48-{[3,4,5-trihydroxy-6-(hydroxymethyl ... 2-[(4-amino-4,6-dimethyl-5-oxooxan-2-yl)oxy]-22-(carbamoylmethyl)-5,47-dichloro-18,32,35,37-tetrahydroxy …
Gildeuretinol
Investigational
4-Aminohydrocinnamic Acid
Experimental
Matched Name: … 4-Aminohydrocinnamic Acid …
Matched Iupac: … 3-(4-aminophenyl)propanoic acid …
Matched Iupac: … 3-(4-aminophenyl)propanoic acid …
Maropitant
Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.
Vet approved
Matched Iupac: … (2S,3S)-N-[(5-tert-butyl-2-methoxyphenyl)methyl]-2-(diphenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine …
D-4-hydroxyphenylglycine
Experimental
Matched Synonyms: … (R)-(4-hydroxyphenyl)glycine ... 4-hydroxy-d-phenylglycine ... D-4-hydroxyphenylglycine …
Matched Name: … D-4-hydroxyphenylglycine …
Matched Iupac: … (2R)-2-amino-2-(4-hydroxyphenyl)acetic acid …
Matched Name: … D-4-hydroxyphenylglycine …
Matched Iupac: … (2R)-2-amino-2-(4-hydroxyphenyl)acetic acid …
N-acetylhistamine
Experimental
Matched Synonyms: … 4-(2-acetamidoethyl)imidazole ... 4-(2-acetylaminoethyl)imidazole ... 4-(beta-Acetylaminoethyl)imidazole …
3,5-Diiodotyrosine
A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE). [PubChem]
Experimental
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid …
Aracytidine 5'-monophosphate
Experimental
Matched Iupac: … {[(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
Experimental
Matched Synonyms: … 4-Methylumbelliferyl α-D-glucoside ... 4-Methylumbelliferyl a-D-glucopyranoside ... 7-(α-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Name: … 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Iupac: … 4-methyl-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …
Matched Name: … 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Iupac: … 4-methyl-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …
5'-Deoxy-5'-(Methylthio)-Tubercidin
Experimental
Matched Iupac: … (2R,3R,4S,5S)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-[(methylsulfanyl)methyl]oxolane-3,4-diol …
Displaying drugs 8901 - 8925 of 12089 in total