Displaying drugs 876 - 900 of 1000 in total
RR001
RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational
Matched Synonyms: … autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …
Mubodina
Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 …
Matched Description: … It was investigated in various conditions including primary membranoproliferative glomerulonephritis and ... It is a recombinant human minibody directed against complement component C5. …
Matched Description: … It was investigated in various conditions including primary membranoproliferative glomerulonephritis and ... It is a recombinant human minibody directed against complement component C5. …
PR1 leukemia peptide vaccine
PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … L-VALINE, L-VALYL-L-LEUCYL-L-GLUTAMINYL-L-.ALPHA. …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …
N-{[6-(PENTYLOXY)NAPHTHALEN-2-YL]SULFONYL}-D-GLUTAMIC ACID
Experimental
Matched Name: … N-{[6-(PENTYLOXY)NAPHTHALEN-2-YL]SULFONYL}-D-GLUTAMIC ACID …
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. ... Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. ... Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
CRS-207
Investigational
Matched Synonyms: … Live-attenuated Listeria monocytogenes actA/inlB/human mesothelin (hMeso) Strain hMeso38 …
Pegvorhyaluronidase alfa
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … PEGylated recombinant human hyaluronidase PH20 ... -METHOXY-, AMIDE WITH HYALURONOGLUCOSAMINIDASE (HUMAN ISOENZYME PH20) ... HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And …
Matched Categories: … Enzymes and Coenzymes …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And …
Matched Categories: … Enzymes and Coenzymes …
Obexelimab
Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human CD19 antigen) (human-mus musculus monoclonal XMAB5871 heavy chain), disulfide ... with human-mus musculus monoclonal XMAB5871 light chain, dimer …
Carotuximab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HUMAN ENDOGLIN (CD105 ANTIGEN)) HUMAN MOUSE CHIMERIC MONOCLONAL ANTIBODY ... IMMUNOGLOBULIN G1, ANTI-(HUMAN ENDOGLIN) (HUMAN-MUS MUSCULUS MONOCLONAL TRC105 HEAVY CHAIN), DISULFIDE ... WITH HUMAN-MUS MUSCULUS MONOCLONAL TRC105 .KAPPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Recombinant human interferon alfa-2a ... Recombinant human interferon-alfa-2a …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Activated charcoal
Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high...
Approved
Matched Description: … oral ingestion of certain medications or poisons by absorbing most drugs and toxins. ... passed over its surface to make a fine network of pores, producing a material with large surface area and ... It is used as a gastric decontaminant and emergency medication to treat poisonings following excessive …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism …
Matched Products: … Humco Charcoal Activated …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism …
Matched Products: … Humco Charcoal Activated …
Efungumab
Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(candida heat-shock protein hsp 90) (human monoclonal hsp90mab fragment) …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins …
NFS-02
NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene (rAAV2-ND1).
Investigational
Matched Synonyms: … recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene …
Matched Description: … NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized …
Matched Description: … NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized …
GYM329
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
2-Hydroxy-5-({1-[(4-Methylphenoxy)Methyl]-3-Oxoprop-1-Enyl}Amino)-L-Tyrosine
Experimental
Matched Name: … 2-Hydroxy-5-({1-[(4-Methylphenoxy)Methyl]-3-Oxoprop-1-Enyl}Amino)-L-Tyrosine …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
BS-001
BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human use (rHSV2hGM-CSF).
Investigational
Matched Synonyms: … Recombinant Oncolytic Herpes Simplex Virus Type II (OH2) Therapeutic Injection (Vero Cell) for Human …
Matched Description: … is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human …
Matched Description: … is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human …
OTL-103
Investigational
Matched Synonyms: … Autologous CD34+ cells transfected with lentiviral vector containing the human WAS cDNA (Telethon 003 …
VaxSyn
VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the National Institute of Allergy and Infectious Diseases (NIAID).
Investigational
Matched Synonyms: … Human T-lymphotropic virus type III Gp160 antigens …
Matched Description: … National Institute of Allergy and Infectious Diseases (NIAID). ... VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the …
Matched Description: … National Institute of Allergy and Infectious Diseases (NIAID). ... VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the …
Hemoglobin crosfumaril
Hemoglobin in which the alpha-subunit are cross-linked intramolecularly.
Experimental
Matched Synonyms: … Hemoglobin A0 (human alpha2 beta2 tetrameric subunit), alpha-chain 99,99'-diamide with (E)-2-butenoic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Related Products ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Related Products ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying …
Matched Description: … [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for ... hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and ... A252797] As opposed to these therapies, valoctocogene roxaparvovec offers the advantage of continuous and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Cellular and Gene Therapy …
Matched Description: … [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for ... hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and ... A252797] As opposed to these therapies, valoctocogene roxaparvovec offers the advantage of continuous and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Cellular and Gene Therapy …
Axalimogene filolisbac
Axalimogene filolisbac is under investigation in clinical trial NCT02853604 (Study of ADXS11-001 in Subjects With High Risk Locally Advanced Cervical Cancer).
Investigational
Matched Synonyms: … Live, attenuated listeria monocytogenes bacteria, expressing human papilloma virus type 16-e7 tumor antigen …
Rexlemestrocel-L
Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell (MPC) product. It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial infarction.
Investigational
Matched Synonyms: … Allogeneic human bone marrow-derived mpc …
Matched Description: … It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial ... Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell …
Matched Description: … It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial ... Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell …
AVE9633
AVE9633 is an anti-CD33 monoclonal antibody-DM4 conjugate.
Investigational
Matched Synonyms: … huMy9-6-DM4 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Idursulfase beta
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Displaying drugs 876 - 900 of 1000 in total