Displaying drugs 876 - 900 of 1297 in total
Frexalimab
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
Matched Synonyms: … Immunoglobulin G1 (272-arginine,325-alanine), anti-(human CD40 ligand) (human-mus musculus monoclonal ... SAR441344 gamma1-chain), disulfide with human-mus musculus monoclonal SAR441344 kappa-chain, dimer …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
L-methionine sulfone
Experimental
Matched Synonyms: … Methionine sulfone …
Matched Name: … L-methionine sulfone …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … L-methionine sulfone …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Apolizumab
Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN HISTOCOMPATIBILITY ANTIGEN HLA-DR) (HUMAN-MOUSE MONOCLONAL HU1D10.GAMMA ... (SUB 1)-CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL HU1D10 LIGHT CHAIN, DIMER …
Matched Description: … Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Unasnemab
Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human repulsive guidance molecule rgma) (human-mus musculus clone rh116a3 .gamma ... .1-chain), disulfide with human-mus musculus clone rh116a3 .kappa. …
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety …
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety …
Galegenimab
Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD)).
Investigational
Matched Synonyms: … Immunoglobulin igg1 fab fragment, anti-(human serine proteinase htra1) (human-mus musculus monoclonal ... fhtr2163 .gamma.1-chain), disulfide with human-mus musculus monoclonal fhtr2163 .kappa. …
Matched Description: … Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and …
Matched Description: … Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and …
Posdinemab
Posdinemab is under investigation in clinical trial NCT04619420 (A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease).
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human phosphorylated tau protein) (human-Mus musculus monoclonal JNJ-63733657 ... γ1-chain), disulfide with human-Mus musculus monoclonal JNJ-63733657 κ-chain, dimer …
Sultamicillin
Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Description: … Pneumonia and Chronic Obstructive Pulmonary Disease (COPD). ... Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated …
Matched Products: … SULCID 375 MG FILM TABLET, 10 ADET ... SULCID 375 MG FILM TABLET, 14 ADET ... SULCID 375 MG FILM TABLET, 20 ADET …
Matched Products: … SULCID 375 MG FILM TABLET, 10 ADET ... SULCID 375 MG FILM TABLET, 14 ADET ... SULCID 375 MG FILM TABLET, 20 ADET …
MK-4721
MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and bladder cancers.
Investigational
Matched Synonyms: … ANTI-PSCA MONOCLONAL ANTIBODY AGS-1C4D4 …
Matched Description: … MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell ... significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell ... significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lucatumumab
Investigational
Matched Synonyms: … Recombinant anti-CD40 monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ruplizumab
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Investigational
Matched Synonyms: … Recombinant humanized monoclonal antibody 5c8 …
Matched Description: … Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
MEDI-6469
MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies).
Investigational
Matched Synonyms: … Agonistic anti-OX40 monoclonal antibody MEDI6469 …
Matched Description: … and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies) ... MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety …
Matched Description: … and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies) ... MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety …
Ivuxolimab
Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Investigational
Matched Synonyms: … Anti-OX40 Antibody PF-04518600 …
Odronextamab
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Matched Synonyms: … Anti-CD20/CD3 monoclonal antibody REGN1979 …
Matched Description: … Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody ... [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, …
Matched Description: … Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody ... [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, …
HLX-58
HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.
Investigational
Matched Synonyms: … Recombinant anti-claudin 18.2 monoclonal antibody …
Matched Description: … HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2. …
Matched Description: … HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2. …
Fianlimab
Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma).
Investigational
Matched Synonyms: … Anti-lag-3 monoclonal antibody regn3767 …
Matched Description: … Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab ... Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma …
Matched Description: … Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab ... Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma …
Plamotamab
Plamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL)).
Investigational
Matched Synonyms: … Anti-cd20/cd3 monoclonal antibody xmab13676 …
Vobramitamab duocarmazine
Vobramitamab duocarmazine is under investigation in clinical trial NCT05551117 (A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors).
Investigational
Matched Synonyms: … Anti-b7h3 antibody-drug conjugate mgc018 …
Matched Description: … Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and …
Matched Description: … Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and …
Volociximab
Investigational
Matched Synonyms: … Anti-alpha5beta1 integrin monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bemarituzumab
Bemarituzumab is under investigation in clinical trial NCT03694522 (A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (Mfolfox6) in Gastric/gastroesophageal Junction Cancer (FIGHT)).
Investigational
Matched Synonyms: … Anti-fgfr2 monoclonal antibody fpa144 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
ATG-101
ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, while delivering enhanced anti-tumor activity, with an improved safety profile.
Investigational
Matched Synonyms: … PD-L1/4-1BB bispecific antibody …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Tidutamab
Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer).
Investigational
Matched Synonyms: … Anti-sstr2/cd3 monoclonal antibody xmab18087 …
Matched Description: … Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab …
Matched Description: … Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab …
Asunercept
Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ontorpacept
Investigational
Matched Synonyms: … (human) fusion protein with immunoglobulin g1 (human fc fragment), dimer …
Displaying drugs 876 - 900 of 1297 in total