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Displaying drugs 9026 - 9050 of 9486 in total

CRS-3123

CRS3123 has been used in trials studying the treatment of Clostridial Infection and Clostridium Difficile Colitis.
Investigational
Matched Iupac: … 5-[(3-{[(4R)-6,8-dibromo-3,4-dihydro-2H-1-benzopyran-4-yl]amino}propyl)amino]-4H,7H-thieno[3,2-b]pyridin …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Antroquinonol

Antroquinonol has been used in trials studying the treatment of Hyperlipidemias, Non-small Cell Lung Cancer, and Non-small Cell Lung Cancer Stage IV.
Investigational
Matched Iupac: … -2-en-1-one ... (4R,5R,6R)-4-hydroxy-2,3-dimethoxy-6-methyl-5-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]cyclohex …

BMS-986115

BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer.
Investigational
Matched Iupac: … (2R,3S)-N-[(3S)-5-(3-fluorophenyl)-9-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-2,3-bis(3,3,3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Rufloxacin

Rufloxacin is a quinolone antibiotic.
Experimental
Matched Iupac: … 7-fluoro-6-(4-methylpiperazin-1-yl)-10-oxo-4-thia-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Regramostim

Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Synonyms: … Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107 …
Matched Description: … Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ …

Osbond acid

Experimental

Oxaloacetic acid

Investigational
Matched Synonyms: … 2-oxobutanedioic acid …
Matched Iupac: … 2-oxobutanedioic acid …

L-proline betaine

Experimental
Matched Synonyms: … (S)-2-carboxylato-1,1-dimethylpyrrolidinium …
Matched Iupac: … (2S)-1,1-dimethylpyrrolidin-1-ium-2-carboxylate …

Tricarballylic acid

Experimental

Aconiazide

Investigational
Matched Synonyms: … Isonicotinic acid (2-(carboxymethoxy)benzylidene)hydrazide …
Matched Iupac: … 2-{2-[(E)-{[(pyridin-4-yl)formamido]imino}methyl]phenoxy}acetic acid …

Dimepheptanol

Dimepheptanol is under investigation in clinical trial NCT00218127 (Treatment of Opioid/heroin Dependence: Comparison of Three Medication Dosing Regimens).
Investigational
Matched Synonyms: … .-(2-(dimethylamino)propyl(-.alpha.-ethyl-.beta.-phenyl- …

Labradimil

Investigational
Matched Iupac: … (2S)-2-{[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{[(2S,4R)-1-[(2S)-1-[(2S)-2-amino-5-[(diaminomethylidene) ... )propanamido]-3-hydroxypropanoyl]pyrrolidin-2-yl]formamido}-3-(4-methoxyphenyl)propyl]amino}-5-[(diaminomethylidene ... amino]pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidin-2-yl]formamido}acetamido)-3-(thiophen-2-yl …

Kitasamycin

Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis.
Experimental
Matched Iupac: … -dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2- ... (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16 …

Rokitamycin

Experimental
Matched Iupac: … -dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2- ... (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16 …

Ularitide

Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Iupac: … ]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-3-hydroxypropanamido]-3-hydroxypropanamido ... ]propanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanamido]-3-hydroxypropanamido]-4-methylpentanamido ... hexadecaazacyclotripentacontan-4-yl]formamido}-3-carbamoylpropanamido]-3-hydroxypropanamido]-3-phenylpropanamido]-5- ... [(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido ... (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(4R,10S,16S,19S,22S,28S,31S,34S,37S,40S,49S,52R)-52-[(2S)-2- …
Matched Description: … Ularitide is currently in Phase 2 development as a potential treatment for patients with acute decompensated …

Dpb-T

Experimental
Matched Iupac: … [(2S,4aS,6S,7aS)-6-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-phenyl-hexahydrofuro[3,2-d ... ][1,3]dioxin-2-yl]phosphonic acid …

beta-D-galactopyranosyl-(1->4)-beta-D-galactopyranose

Experimental
Matched Iupac: … (2R,3R,4R,5R,6R)-6-(hydroxymethyl)-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy …

Serine-3'-aminoadenosine

Experimental
Matched Iupac: … (2S)-2-amino-N-[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-hydroxypropanamide …

Debromohymenialdisine

Experimental
Matched Iupac: … 2-amino-5-[(4Z)-8-oxo-1H,4H,5H,6H,7H,8H-pyrrolo[2,3-c]azepin-4-ylidene]-4,5-dihydro-1H-imidazol-4-one …

Marbofloxacin

Marbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under the name Aurizon.
Vet approved
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1,2-diazatricyclo[7.3.1.0⁵,¹³]trideca-5(13) …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cilengitide

Cilengitide has been used in trials studying the treatment of Sarcoma, Gliomas, Lymphoma, Leukemia, and Lung Cancer, among others.
Investigational
Matched Iupac: … 2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopropyl)-7-methyl-3,6,9,12,15-pentaoxo-8-(propan-2-yl) ... -1,4,7,10,13-pentaazacyclopentadecan-2-yl]acetic acid …

LY-3023414

LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.
Investigational
Matched Iupac: … 8-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methyl-1H,2H,3H-imidazo[4,5-c]quinolin ... -2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

GDC-0810

ARN-810 has been used in trials studying the basic science and treatment of Breast Cancer.
Investigational
Matched Iupac: … (2E)-3-{4-[(1E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl]phenyl}prop-2-enoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Galicaftor

Galicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in Patients With Cystic Fibrosis.).
Investigational
Matched Iupac: … -2H-1-benzopyran-2-yl]benzoic acid ... 4-[(2R,4R)-4-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-7-(difluoromethoxy)-3,4-dihydro …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Allosamidin

Allosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
Experimental
Matched Iupac: … ,6aH-cyclopenta[d][1,3]oxazol-5-yl]oxy}-5-{[(2S,3R,4S,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl ... N-[(2R,3R,4S,5S,6R)-2-{[(3aR,4R,5R,6S,6aS)-2-(dimethylamino)-4-hydroxy-6-(hydroxymethyl)-3aH,4H,5H,6H ... )oxan-2-yl]oxy}-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide …
Displaying drugs 9026 - 9050 of 9486 in total