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Displaying drugs 9051 - 9075 of 11684 in total

D-Proline

D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva . These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity .
Experimental
Matched Synonyms: … (R)-2-Carboxypyrrolidine ... (2R)-pyrrolidine-2-carboxylic acid ... (R)-pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R)-pyrrolidine-2-carboxylic acid …

N-Carbamoylphenylalanine

Experimental
Matched Iupac: … (2S)-2-(carbamoylamino)-3-phenylpropanoic acid …

Ethoxyquin

Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

ICG-136

ICG-136 is a compound chimeric antigen receptor (cCAR) T-cell therapy developed by iCell Gene Therapeutics. It was investigated for the treatment of acute myeloid leukemia.
Investigational

N-methyl-1-(2-thiophen-2-ylphenyl)methanamine

Experimental
Matched Name: … N-methyl-1-(2-thiophen-2-ylphenyl)methanamine …
Matched Iupac: … methyl({[2-(thiophen-2-yl)phenyl]methyl})amine …

IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE

Experimental
Matched Name: … IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE …
Matched Iupac: … imidazo[2,1-a]isoquinoline-2-carbohydrazide …

4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine

Experimental
Matched Name: … 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine …
Matched Iupac: … 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine …

Prostaglandin B2

Experimental
Matched Iupac: … (5Z)-7-{2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoic acid …

2-Dehydropantoate

Experimental
Matched Name: … 2-Dehydropantoate …
Matched Iupac: … 4-hydroxy-3,3-dimethyl-2-oxobutanoic acid …

LY2181308

LY2181308 is investigated in clinical trials for treating solid tumors. LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. LY2181308 is known to target baculoviral IAP repeat-containing protein 5. LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung,...
Investigational
Matched Description: … LY2181308 is known to target baculoviral IAP repeat-containing protein 5. …

LY2275796

LY2275796 is a second-generation antisense anti-cancer drug candidate for clinical development. LY2275796 targets eukaryotic initiation factor- 4E (eIF-4E), a protein involved in the translation of key growth and survival factors that drive tumor progression, angiogenesis and metastases.
Investigational

LY2828360

LY2828360 is under investigation in clinical trial NCT01319929 (A Study of LY2828360 in Patients With Osteoarthritic Knee Pain).
Investigational
Matched Iupac: … 8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)-9H-purine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

BDBM249432

Investigational

Bardoxolone

Bardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors. It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in cancer cells that are under high levels of intrinsic oxidative stress. In contrast, Bardoxolone in...
Investigational

2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE

Experimental
Matched Name: … 2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE …
Matched Iupac: … 2-(2-methylphenyl)-1H-indole-6-carboximidamide …

Triglu-5-formyl-tetrahydrofolate

Experimental
Matched Name: … Triglu-5-formyl-tetrahydrofolate …
Matched Iupac: … (2S)-2-[(4S)-4-[(4S)-4-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino …

Cytidine-5'-diphospho-beta-D-xylose

Experimental
Matched Name: … Cytidine-5'-diphospho-beta-D-xylose …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy ... ({[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …

6-Methylamino-5-Nitroisocytosine

Experimental
Matched Name: … 6-Methylamino-5-Nitroisocytosine …
Matched Iupac: … 2-amino-6-(methylamino)-5-nitro-3,4-dihydropyrimidin-4-one …

5-Aminoimidazole Ribonucleoside

Experimental
Matched Name: … 5-Aminoimidazole Ribonucleoside …
Matched Iupac: … (2R,3R,4S,5R)-2-(5-amino-1H-imidazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol …

methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate

Experimental
Matched Name: … methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate …
Matched Iupac: … methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane- …

Bitolterol

Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Synonyms: … 4-(2-(tert-butylamino)-1-hydroxyethyl)-o-phenylene di-p-toluate ... 4-[2-(tert-butylamino)-1-hydroxyethyl]-o-phenylene di-p-toluate ... bis(4-methylbenzoic acid) 4-[2-(tert-butylamino)-1-hydroxyethyl]-1,2-phenylene ester …
Matched Iupac: … 5-[2-(tert-butylamino)-1-hydroxyethyl]-2-(4-methylbenzoyloxy)phenyl 4-methylbenzoate …
Matched Description: … It is a beta-2-adrenergic receptor agonist. …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …

3,4-Dihydroxybenzoic Acid

Experimental

A-dmDT390-bisFv(UCHT1)

A-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides).
Investigational

Cibisatamab

Investigational

Inositol 1,3-Bisphosphate

Experimental
Matched Iupac: … {[(1S,2R,3s,4S,5R,6s)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
Displaying drugs 9051 - 9075 of 11684 in total