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Displaying drugs 9126 - 9150 of 9972 in total

4'-Methylene-5,8,10-trideazaaminopterin

CH-1504 is a an antirheumatic agent that has been shown in vitro to be a nonpolyglutamylatable and nonhydroxylatable antifolate that is more efficiently taken up into cells by the reduced folate carrier (RFC) system than is Methotrexate. It has been investigated for the treatment of Rheumatoid Arthritis (phase II).
Investigational

alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acid

Experimental
Matched Synonyms: … 3-(4-diethylamino-2-hydroxy-phenyl)-2-methyl-propionic acid …
Matched Iupac: … (2E)-3-[4-(diethylamino)-2-hydroxyphenyl]-2-methylprop-2-enoic acid …

Fresolimumab

Fresolimumab has been used in trials studying the treatment of Primary Brain Tumors, Metastatic Breast Cancer, Diffuse Systemic Sclerosis, Pleural Malignant Mesothelioma, and Primary Focal Segmental Glomerulosclerosis.
Investigational

Golnerminogene pradenovec

Investigational

D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide

Experimental
Matched Name: … D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-[(3-methylphenyl)methyl]pyrrolidine-2-carboxamide …

4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine

Experimental
Matched Name: … 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine …
Matched Iupac: … 4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine …

5-Amino-3-Methyl-Pyrrolidine-2-Carboxylic Acid

Experimental
Matched Name: … 5-Amino-3-Methyl-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5R)-5-amino-3-methylpyrrolidine-2-carboxylic acid …

D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide

Experimental
Matched Name: … D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-[(3-fluorophenyl)methyl]pyrrolidine-2-carboxamide …

6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE

Experimental
Matched Name: … 6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE …
Matched Iupac: … N-(3-chlorophenyl)-6-(cyclohexylmethoxy)-7H-purin-2-amine …

N(6)-(pyridoxal phosphate)-L-lysine

Experimental
Matched Synonyms: … N6-((3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methylene)-L-lysine ... (S)-2-amino-6-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-4-pyridine)methyleneamino]hexanoic acid …
Matched Iupac: … (2S)-2-amino-6-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]hexanoic …

Opaganib

Opaganib, also known as ABC294640, is a selective sphingosine kinase-2 (SK2) (https://go.drugbank.com/polypeptides/Q9NRA0) inhibitor that is orally administered. This drug has potential anticancer, anti-inflammatory, and antiviral activities, with potential applications in oncology, inflammation, the gastrointestinal system, and COVID-19.
Investigational
Matched Synonyms: … 4-Pyridinylmethyl 3(4-Chlorophenyl)Adamantine Carboxamide ... 4-Pyridinylmethyl-3-(4-Chlorophenyl) Adamantine Carboxamide …
Matched Iupac: … 3-(4-chlorophenyl)-N-[(pyridin-4-yl)methyl]adamantane-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Apitolisib

Apitolisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Prostate Cancer, Renal Cell Carcinoma, and Endometrial Carcinoma, among others.
Investigational
Matched Iupac: … (2S)-1-(4-{[2-(2-aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}piperazin ... -1-yl)-2-hydroxypropan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …

Sitravatinib

Sitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma).
Investigational
Matched Iupac: … N'1-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

RO-6870810

RO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Investigational
Matched Iupac: … (6),4,7,10,12-pentaen-9-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide ... 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tifuvirtide

Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Investigational

beta-D-galactopyranosyl-(1->4)-beta-D-galactopyranose

Experimental
Matched Synonyms: … β-D-Galp-(1→4)-β-D-Galp ... β-D-galactopyranosyl-(1→4)-β-D-galactopyranose …
Matched Name: … beta-D-galactopyranosyl-(1->4)-beta-D-galactopyranose …

COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection

As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Investigational

Pralnacasan

Pralnacasan is an orally bioavailable pro-drug of a potent, non-peptide inhibitor of interleukin-1beta converting enzyme (ICE).
Investigational
Matched Iupac: … [1,2]diazepin-7-yl]isoquinoline-1-carboxamide ... N-[(4S,7S)-4-{[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]carbamoyl}-6,10-dioxo-octahydro-1H-pyridazino[1,2-a] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Funapide

Funapide has been used in trials studying the treatment of Pharmacokinetics, Postherpetic Neuralgia, and Osteoarthritis of the Knee.
Investigational
Matched Iupac: … [7.3.0.0^{3,7}]dodecane]-1',3'(7'),8'-trien-2-one ... (3S)-1-{[5-(trifluoromethyl)furan-2-yl]methyl}-1,2-dihydro-6',10',12'-trioxaspiro[indole-3,4'-tricyclo …

PF-03814735

PF-03814735 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Iupac: … [4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-11-azatricyclo[6.2.1.0^{2,7}]undeca-2(7) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ginsenosides

Dammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol.
Experimental
Matched Iupac: … -1H-cyclopenta[a]phenanthren-7-ol ... (1S,3aR,3bR,5aR,7S,9aR,9bR)-1-(2-hydroxy-6-methylhept-5-en-2-yl)-3a,3b,6,6,9a-pentamethyl-hexadecahydro …

3-Methyl-5-Sulfo-Pyrrolidine-2-Carboxylic Acid

Experimental
Matched Name: … 3-Methyl-5-Sulfo-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5S)-3-methyl-5-sulfopyrrolidine-2-carboxylic acid …

[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate

Experimental
Matched Iupac: … (9Z)-octadec-9-en-1-yl (2R)-2,3-dihydroxypropanoate …

3-(Phosphonomethyl)Pyridine-2-Carboxylic Acid

Experimental
Matched Name: … 3-(Phosphonomethyl)Pyridine-2-Carboxylic Acid …
Matched Iupac: … 3-(phosphonomethyl)pyridine-2-carboxylic acid …

D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide

Experimental
Matched Name: … D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Displaying drugs 9126 - 9150 of 9972 in total