Ginsenosides

Identification

Generic Name

Ginsenosides

DrugBank Accession Number

DB14152

Background

Dammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol.

Type

Small Molecule

Groups

Experimental

Structure

3D

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MOLSDF3D-SDFPDBSMILESInChI

Similar Structures

Structure for Ginsenosides (DB14152)

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Weight

Average: 444.744
Monoisotopic: 444.396730914

Chemical Formula

C₃₀H₅₂O₂

Synonyms

• Ginseng root-neutral saponins
• Ginsenoside
• Neutral saponins of panax ginseng root

External IDs

• BM-RE60
• KG 135

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Not Available

Food Interactions

Not Available

Products

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Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Qwg-1000	Liquid	0.04 g/100mL	Topical	Institute of Quantum Bioscience	2022-11-20	Not applicable
Ruby Cell 4u Rg3 Pure	Soap	0.7 g/100g	Topical	Dasan E&T Co., Ltd.	2014-12-01	2017-12-01

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
Herbal Iron Brilliant Performance for Brightening and Wrinkle Free	Ginsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)	Kit	Topical	Btgin Co.,Ltd	2017-03-27	Not applicable
Herbal Iron Brilliant Performance for Brightening and Wrinkle Free	Ginsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)	Kit	Topical	Btgin Co.,Ltd	2017-03-27	Not applicable
Herbal Iron Brilliant Performance for Brightening and Wrinkle Free	Ginsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)	Kit	Topical	Btgin Co.,Ltd	2017-03-27	Not applicable
Herbal Iron Brilliant Performance for Brightening and Wrinkle Free	Ginsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)	Kit	Topical	Btgin Co.,Ltd	2017-03-27	Not applicable
HERBAL IRON Enriched Moisture	Ginsenosides (0.05 g/100mL) + Adenosine (0.04 g/100mL)	Emulsion	Topical	Btgin Co.,Ltd	2017-03-16	2017-03-27
HERBAL IRON Enriched Moisture Skin Toner	Ginsenosides (0.05 g/100mL) + Adenosine (0.04 g/100mL)	Liquid	Topical	Btgin Co.,Ltd	2017-03-16	2017-03-27
Qwg-1000	Ginsenosides (0.04 g/100mL) + Adenosine (2 g/100mL)	Liquid	Topical	Institute of Quantum Bioscience	2022-11-20	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
Herbal Iron Brilliant Performance for Brightening and Wrinkle Free	Ginsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)	Kit	Topical	Btgin Co.,Ltd	2017-03-27	Not applicable
Herbal Iron Brilliant Performance for Brightening and Wrinkle Free	Ginsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)	Kit	Topical	Btgin Co.,Ltd	2017-03-27	Not applicable
Herbal Iron Brilliant Performance for Brightening and Wrinkle Free	Ginsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)	Kit	Topical	Btgin Co.,Ltd	2017-03-27	Not applicable
Herbal Iron Brilliant Performance for Brightening and Wrinkle Free	Ginsenosides (0.05 g/100mL) + Ginsenosides (0.05 g/100mL) + Ginsenosides (0.1 g/100mL) + Ginsenosides (0.1 g/100g) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100mL) + Adenosine (0.04 g/100g)	Kit	Topical	Btgin Co.,Ltd	2017-03-27	Not applicable
HERBAL IRON Enriched Moisture	Ginsenosides (0.05 g/100mL) + Adenosine (0.04 g/100mL)	Emulsion	Topical	Btgin Co.,Ltd	2017-03-16	2017-03-27
HERBAL IRON Enriched Moisture Skin Toner	Ginsenosides (0.05 g/100mL) + Adenosine (0.04 g/100mL)	Liquid	Topical	Btgin Co.,Ltd	2017-03-16	2017-03-27
Qwg-1000	Ginsenosides (0.04 g/100mL) + Adenosine (2 g/100mL)	Liquid	Topical	Institute of Quantum Bioscience	2022-11-20	Not applicable
Qwg-1000	Ginsenosides (0.04 g/100mL)	Liquid	Topical	Institute of Quantum Bioscience	2022-11-20	Not applicable
Ruby Cell 4u Rg3 Pure	Ginsenosides (0.7 g/100g)	Soap	Topical	Dasan E&T Co., Ltd.	2014-12-01	2017-12-01

Categories

Drug Categories

• Carbohydrates
• Glycosides
• Saponins
• Terpenes
• Triterpenes

Classification

Not classified

Affected organisms

Not Available

Chemical Identifiers

UNII

3K198YD54P

CAS number

74749-74-9

InChI Key

NLHQJXWYMZLQJY-SWIZOJJJSA-N

InChI

InChI=1S/C30H52O2/c1-20(2)10-9-16-30(8,32)22-13-18-28(6)21(22)11-12-24-27(5)17-15-25(31)26(3,4)23(27)14-19-29(24,28)7/h10,21-25,31-32H,9,11-19H2,1-8H3/t21?,22-,23-,24+,25-,27-,28+,29+,30?/m0/s1

IUPAC Name

(1S,3aR,3bR,5aR,7S,9aR,9bR)-1-(2-hydroxy-6-methylhept-5-en-2-yl)-3a,3b,6,6,9a-pentamethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-ol

SMILES

[H][C@@]1(CC[C@]2(C)C1([H])CC[C@]1([H])[C@@]3(C)CC[C@]([H])(O)C(C)(C)[C@]3([H])CC[C@@]21C)C(C)(O)CCC=C(C)C

References

General References

Not Available

External Links

ChemSpider

2342730

RxNav

349656

Wikipedia

Ginsenoside

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count
4	Completed	Treatment	Fatigue	1
2	Unknown Status	Treatment	Non-Small Cell Lung Cancer (NSCLC)	1
Not Available	Completed	Not Available	Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) / Apoptosis / Immunosuppression / Neutrophils / Pathogenesis	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Kit	Topical
Emulsion	Topical
Liquid	Topical
Liquid	Topical	0.04 g/100mL
Soap	Topical	0.7 g/100g

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	0.000182 mg/mL	ALOGPS
logP	6.39	ALOGPS
logP	6.84	Chemaxon
logS	-6.4	ALOGPS
pKa (Strongest Acidic)	19.49	Chemaxon
pKa (Strongest Basic)	-0.26	Chemaxon
Physiological Charge	0	Chemaxon
Hydrogen Acceptor Count	2	Chemaxon
Hydrogen Donor Count	2	Chemaxon
Polar Surface Area	40.46 Å2	Chemaxon
Rotatable Bond Count	4	Chemaxon
Refractivity	135.64 m3·mol-1	Chemaxon
Polarizability	55.91 Å3	Chemaxon
Number of Rings	4	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	No	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Not Available

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Drug created at June 28, 2018 21:54 / Updated at June 12, 2020 16:53