Displaying drugs 901 - 925 of 1119 in total
Uttroside B
Investigational
Matched Synonyms: … .,5.alpha.,22.alpha.,25r)-26-(.beta.-d-glucopyranosyloxy)-22-hydroxyfurostan-3-yl o-.beta. …
TOL-101
Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
QXL138AM
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Matched Synonyms: … Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha …
Matched Description: … masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha …
Matched Description: … masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha …
Eflornithine
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … alpha-difluoromethylornithine …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... under the brand name IWILFIN as an oral maintenance therapy to reduce the risk of relapse in adult and …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... under the brand name IWILFIN as an oral maintenance therapy to reduce the risk of relapse in adult and …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …
1,2-Di-N-Pentanoyl-Sn-Glycero-3-Dithiophosphocholine
Experimental
Matched Name: … 1,2-Di-N-Pentanoyl-Sn-Glycero-3-Dithiophosphocholine …
ACV tripeptide
Experimental
Matched Synonyms: … (alpha-Aminoadipyl)-cys-val ... L-delta-(alpha-Aminoadipoyl)-L-cysteinyl-D-valine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Fenvalerate
Investigational
Matched Synonyms: … (rs)-.alpha.-cyano-3-phenoxybenzyl (rs)-2-(4-chloro-phenyl)-3-methylbutyrate ... (.alpha.rs)-.alpha.-cyano-3-phenoxybenzyl (2rs)-2-(4-chlorophenyl)-3-methylbutyrate ... Cyano(3-phenoxyphenyl)methyl 4-chloro-.alpha.-(1-methylethyl)benzeneacetate …
ALT-P1
ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Recombinant human growth hormone fused to alpha1-antitrypsin variant …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein ... Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2 …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. ... D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA. …
Matched Description: … M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... of breath and the coughing up of blood. ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. …
Matched Categories: … cefepime and amikacin …
Matched Description: … M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... of breath and the coughing up of blood. ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. …
Matched Categories: … cefepime and amikacin …
1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate
Experimental
Matched Name: … 1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate …
1-ACETYL-2-LYSO-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
Experimental
Matched Name: … 1-ACETYL-2-LYSO-SN-GLYCERO-3-PHOSPHOETHANOLAMINE …
L-Pentahomoserine
Experimental
Matched Synonyms: … L-alpha-Amino-delta-hydroxyvaleric acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
Experimental
Matched Name: … 6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE …
Dexmedetomidine
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Synonyms: … (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole …
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
(2S)-2,3-Diaminobutanoic acid
Experimental
Matched Synonyms: … L-Threo-alpha,beta-diaminobutyric acid …
PTR-01
Investigational
Matched Synonyms: … Recombinant human collagen alpha-1 (VII) chain homo-trimer (rC7) …
Voriconazole
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Synonyms: … (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol …
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [ …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... 14-alpha Demethylase Inhibitors …
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [ …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... 14-alpha Demethylase Inhibitors …
Oxogluric acid
Oxogluric acid (α-Ketoglutarate) is not approved for any indication in the world but is an investigational drug in the United States. In the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplements can benefit patients with the metabolic disorder propionic acidemia. Oxogluric...
Experimental
Investigational
Nutraceutical
Matched Synonyms: … alpha-Ketoglutaric acid …
Matched Description: … performance by helping to remove excess ammonia, but it is not officially approved for this indication and ... transamination reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and …
Matched Description: … performance by helping to remove excess ammonia, but it is not officially approved for this indication and ... transamination reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and …
Celastrol
Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.
Investigational
Matched Synonyms: … .,13.alpha.,14.beta.,20.alpha.)- …
Etavopivat
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4 …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) …
2-deoxy-2-fluoro-alpha-D-mannosyl fluoride
Experimental
Matched Name: … 2-deoxy-2-fluoro-alpha-D-mannosyl fluoride …
7-alpha-D-Ribofuranosyl-2-aminopurine-5'-phosphate
Experimental
Matched Name: … 7-alpha-D-Ribofuranosyl-2-aminopurine-5'-phosphate …
Displaying drugs 901 - 925 of 1119 in total