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Displaying drugs 901 - 925 of 1326 in total
Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Synonyms: … Anti-tgf-beta monoclonal antibody nis793 …
Matched Description: … in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy ... Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … EXEMESTAN BETA 25MG ... EXEMESTAN BETA 25MG FTA …
Nicoboxil has been investigated for the treatment of Acute Low Back Pain, where it is typically considered an effective and safe therapeutic option. Nevertheless, it is predominantly found paired with nonivamide as a combination topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and ultimately...
Approved
Investigational
Matched Synonyms: … beta-Butoxyethyl nicotinate …
Matched Description: … of Europe and Asia, like Germany and Australia [F11, F16]. ... investigated for the treatment of Acute Low Back Pain, where it is typically considered an effective and ... topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and
Investigational
Matched Synonyms: … Beta-Caryophyllene …
2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma, among others.
Investigational
Matched Synonyms: … 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil ... 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil …
Matched Description: … Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
Approved
Investigational
Matched Synonyms: … beta-betulinic acid …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … 2-amino-2-deoxy-beta-D-galactopyranose …
Matched Name: … beta-D-Galactosamine …
Experimental
Matched Name: … Methyl beta-galactoside …
Experimental
Matched Name: … beta-D-fucose …
Investigational
Matched Name: … 7-beta-Hydroxyepiandrosterone …
Investigational
Matched Name: … Sulfobutylether-beta-cyclodextrin …
Experimental
Matched Name: … beta-D-galactopyranosyl-(1->4)-beta-D-galactopyranose …
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Description: … side effects, notably gastrointestinal hypomotility and orthostatic hypotension. ... particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and ... [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … CLOZAPIN BETA 25MG ... CLOZAPIN BETA 50MG ... CLOZAPIN BETA 100MG …
CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Investigational
Matched Name: … CAR BCMA-CS1 …
Matched Description: … B-cell maturation antigen and CS1. ... CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target …
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Experimental
Matched Synonyms: … beta-NAD ... beta-NAD+ ... beta-Diphosphopyridine nucleotide …
Matched Description: … electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an …
Matched Mixtures name: … Bonogen hair care shampoo ... Bonogen Plus hair care shampoo …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Synonyms: … A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7 …
Matched Name: … Anti-CD7 CAR T-cell therapy …
CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Investigational
Matched Synonyms: … Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
Experimental
Matched Synonyms: … 1,4-deoxy-1,4-dithio-beta-D-glucopyranose …
Matched Name: … 1,4-dithio-beta-D-glucopyranose …
Experimental
Matched Synonyms: … N-benzoyl-N'-beta-D-glucopyranosyl urea …
Matched Name: … N-(Benzoylcarbamoyl)-beta-D-glucopyranosylamine …
Experimental
Matched Synonyms: … 2-deoxy-2-fluoro-beta-D-mannose …
Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from the alpha form on the position of one methyl group. To know more about the mixture please visit DB01049
Approved
Matched Synonyms: … dihydro-beta-ergocryptine …
Matched Description: … Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro …
CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD19 antigen …
Matched Description: … CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … beta-(4-Chlorophenyl)gaba ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid ... beta-(p-Chlorophenyl)-gamma-aminobutyric acid …
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Synonyms: … beta-Arbutin ... 4-Hydroxyphenyl-beta-D-glucopyranoside ... Hydroquinone-O-beta-D-glucopyranoside …
Matched Description: … in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526]. ... and [DB09526] [F43]. ... Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly …
Matched Mixtures name: … Reoganic EX Whitening Pore Care Deodorant …
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids,...
Experimental
Illicit
Matched Synonyms: … beta-meprodine ... beta-1-Methyl-3-ethyl-4-phenyl-4-propionoxy-piperidin ... beta-3-Ethyl-1-methyl-4-phenyl-4-propionoxypiperidine …
Matched Description: … as well as itching, nausea, and respiratory depression. ... The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Displaying drugs 901 - 925 of 1326 in total