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Displaying drugs 901 - 925 of 1390 in total
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. …
Matched Products: … Esmolol Hydrochloride In Sodium Chloride
Investigational
Matched Synonyms: … Ciliary neurotrophic factor, recombinant human
Matched Name: … Human ciliary neurotrophic factor, recombinant (E. coli) …
Investigational
Matched Synonyms: … HEMOPEXIN (HUMAN) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … RECOMBINANT HUMAN PLACENTAL GROWTH FACTOR …
Matched Name: … Recombinant human placental growth factor (PLGF-131) …
Amniotic epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human amnion, the layer of the placenta closest to the fetus.[A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine due to their potential for differentiation and multiplication.
Investigational
Matched Synonyms: … Human Amniotic Epithelial Cells …
Matched Description: … due to their potential for differentiation and multiplication. ... [A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine ... epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human
Investigational
Matched Synonyms: … Recombinant human biglycan …
CAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen.
Investigational
Matched Synonyms: … fibrinogen-depleted human platelet lysate …
Matched Description: … CAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen. …
Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da. Fibrinolysin is used as a...
Investigational
Matched Synonyms: … Fibrinolysin, human ... Fibrinolysin (human) …
Matched Description: … Fibrinolysin and deoxyribonuclease both act as lytic enzymes. ... Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. ... The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... fibrinolysin and desoxyribonuclease …
Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human cd antigen cd37) (synthetic human-mus musculus fragment tru-016), dimer …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Recombinant methionyl human bdnf ... Recombinant methionyl human brain-derived neurotrophic factor …
Investigational
Matched Synonyms: … Human allogeneic bone marrow derived osteoblastic cells ... Human allogeneic bone-marrow-derived osteoblastic cells …
Matched Name: … Human allogeneic bone marrow derived osteoblastic cells …
Andecaliximab is a monoclonal antibody directed against matrix metallopeptidase 9 (MMP9). Andecaliximab is under investigation in clinical trial NCT03631836 (Phase I Study of Monoclonal Antibondy (GS) 5745, an Matix Metalloproteinase 9 (MMP9) Mab Inhibitor, in Combination With Bevacizumab in Patients With Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human gelatinase b) (human-mus musculus monoclonal gs-5745 heavy chain), disulfide ... with human-mus musculus monoclonal gs-5745 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN SERUM ALBUMIN) (HUMAN-LAMA GLAMA MONOCLONAL ALXN1720 SINGLE-DOMAIN ... COMPLEMENT C5) (HUMAN-LAMA GLAMA MONOCLO ... VHH FRAGMENT) FUSION PROTEIN WITH PEPTIDE LINKER (SYNTHETIC 15 AMINO-ACID) FUSION PROTEIN WITH ANTI-(HUMAN
Matched Description: … Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in …
Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Description: … , and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. ... Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker ... [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension …
Matched Mixtures name: … Hypertenevide-12.5 ... CARIVALAN 12.5/5 ... CARIVALAN 12.5/7.5 …
Matched Categories: … Alpha and Beta Blocking Agents ... carvedilol and ivabradine ... Calcium-Regulating Hormones and Agents …
Matched Products: … CARVEDILOL 1A PHARMA 12.5 ... Carvedilol "1A Pharma" 12,5 mg - Tabletten ... CARVEDILOL 1A PHARMA 25MG …
Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Description: … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. ... The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011. …
Matched Categories: … Blood and Blood Forming Organs ... rivaroxaban and acetylsalicylic acid …
Matched Products: … Rivaroxaban 1A Pharma 10 mg – Filmtabletten ... Rivaroxaban 1A Pharma 15 mg – Filmtabletten ... Rivaroxaban 1A Pharma 20 mg - Filmtabletten …
Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly...
Approved
Vet approved
Matched Description: … Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged ... Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate …
Matched Categories: … Piperazine and Derivatives ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Veriga 125 ... PIPERAZINA 12% …
H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine . It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferential targeting . H3B-8800 was granted orphan drug status by the FDA in August 2017 and...
Investigational
Matched Synonyms: … (2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(2-pyridinyl)-2,4-heptadien-2 ... (2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-Dimethyl-12-Oxo-2-[(2E,4E,6R)-6-(Pyridin-2-Yl)Hepta-2,4-Dien- ... 4E,6S,7R,10R)-7,10-DIHYDROXY-3,7-DIMETHYL-2-((1E,3E,5R)-1-METHYL-5-(2-PYRIDINYL)-1,3-HEXADIEN-1-YL)-12
Matched Iupac: … (2S,3S,4E,6S,7R,10R)-7,10-dihydroxy-3,7-dimethyl-12-oxo-2-[(4E,6R)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl …
Matched Description: … of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551]. ... H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment …
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Description: … emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin ... considered the most effective and first-line treatment for ADHD in adults and children as recommended ... addictive properties, and even amplifies the potency and reinforcing effects of other drugs of abuse …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … ATOMOXE 1A PHARMA 10MG ... ATOMOXE 1A PHARMA 18MG ... ATOMOXE 1A PHARMA 25MG …
Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).
Investigational
Matched Synonyms: … 2) (human-mus musculus monoclonal clone nvs260714 .gamma.4-chain), disulfide with human-mus musculus ... Immunoglobulin g4 (226-proline,de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and
Matched Categories: … Serotonin Agents ... Serotonin Modulators ... Selective Serotonin Reuptake Inhibitors ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … SEROXAT CR TABLET 12.5 mg ... PAXIL CR 12.5 MG KONTROLLÜ SALIMLI TABLET, 28 ADET ... PAROXETIN 1A PHARMA 10MG …
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist ... sumatriptan and naproxen ... Genito Urinary System and Sex Hormones ... Serotonin Agents ... Serotonin Modulators …
Matched Products: … Imitrex Inj 12mg/ml ... SUMATRIPTAN 1A PHAR 50MG ... SUMATRIPTAN 1A PHAR 100MG …
Posdinemab is under investigation in clinical trial NCT04619420 (A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease).
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human phosphorylated tau protein) (human-Mus musculus monoclonal JNJ-63733657 ... γ1-chain), disulfide with human-Mus musculus monoclonal JNJ-63733657 κ-chain, dimer …
Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) . It was first approved by the FDA in 1997 . Parkinson's Disease is...
Approved
Investigational
Matched Description: … agonist_ drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and ... Parkinson's Disease is one of the most common neurodegenerative disorders and causes a high level of …
Matched Products: … PRAMIPEXOL 1A PHARMA 0.26 ... PRAMIPEXOL 1A PHARMA 2.1MG ... PRAMIPEXOL 1A PHARMA0.26MG …
ATI-1013 is a fully human nicotine-specific monoclonal antibody.
Investigational
Matched Synonyms: … Fully human nicotine-specific monoclonal antibody …
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 901 - 925 of 1390 in total