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Displaying drugs 9376 - 9400 of 9650 in total

Preimplantation factor

Preimplantation factor is under investigation in clinical trial NCT03593460 (Phase II Autoimmune Hepatitis).
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-6-amino-2-[ ... -3-carbamoylpropanamido]hexanoyl]pyrrolidin-2-yl]formamido}-3-hydroxypropanamido]-3-carboxypropanamido ... ]-3-methylpentanamido]hexanoyl]pyrrolidin-2-yl]formamido}acetamido)-3-hydroxypropanamido]propanamido] ... (2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-3-methylbutanamido]-5-carbamimidamidopentanamido …

Phosphorylcolamine

Experimental
Matched Synonyms: … 2-aminoethyl dihydrogen phosphate …
Matched Iupac: … (2-aminoethoxy)phosphonic acid …

N-Carbamoylaspartic acid

Experimental
Matched Synonyms: … 2-Ureidobutanedioic acid …
Matched Iupac: … (2S)-2-(carbamoylamino)butanedioic acid …

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational

Heparin Disaccharide Iii-S

Experimental
Matched Iupac: … -3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate ... (2R,3R,4S)-2-{[(2R,3S,4R,5R,6S)-4,6-dihydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)oxan-3-yl]oxy}-4-hydroxy …

(C8-R)-hydantocidin 5'-phosphate

Experimental
Matched Iupac: … -3-yl]-2-[N-hydroxy-N-(hydroxymethyl)amino]pentanoic acid ... (2R)-5-[(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-7-[(phosphonooxy)methyl]-6-oxa-1,3-diazaspiro[4.4]nonan …

Plevitrexed

Investigational
Matched Iupac: … (2S)-2-[(4-{[(2,7-dimethyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}-2-fluorophenyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Orvepitant

Orvepitant has been used in trials studying the treatment of Depressive Disorder, Depressive Disorder, Major, Post-Traumatic Stress Disorder, and Posttraumatic Stress Disorder (PTSD).
Investigational
Matched Iupac: … (2R,4S)-4-[(8aS)-6-oxo-octahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl ... ]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide …

CEP-9722

CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
Investigational
Matched Iupac: … nonadeca-1(12),2(6),7(11),13(18),14,16-hexaene-8,10-dione ... 14-methoxy-9-[(4-methylpiperazin-1-yl)methyl]-9,19-diazapentacyclo[10.7.0.0^{2,6}.0^{7,11}.0^{13,18}] …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …

Relacorilant

Relacorilant is under investigation in clinical trial NCT02804750 (Study to Evaluate CORT125134 in Patients With Cushing's Syndrome).
Investigational
Matched Iupac: … 2-[(4aR)-1-(4-fluorophenyl)-6-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-1H,4H,4aH,5H,6H,7H,8H-pyrido[3,4-f …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tropifexor

Tropifexor is under investigation in clinical trial NCT02516605 (A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients).
Investigational
Matched Iupac: … 2-[(1R,3R,5S)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[ ... 3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ethanesulfonic acid

Experimental
Matched Synonyms: … 2-ethanesulfonic acid …

TN-401

TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational

Concanamycin A

Concanamycin A is an H+-ATPase (vacuolar) inhibitor.
Experimental
Matched Iupac: … -2-yl]-2-hydroxy-5-methyl-6-(prop-1-en-1-yl)oxan-4-yl]oxy}-4-hydroxy-2-methyloxan-3-yl carbamate ... (2R,3S,4R,6R)-6-{[(2R,4R,5S,6R)-2-[(2S,3R,4S)-4-[(2R,3S,4E,6E,9R,10S,11S,12R,13R,14E,16Z)-11-ethyl-10,12 ... -dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan …

ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE

Experimental
Matched Name: … ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE …
Matched Iupac: … ethyl 4-[(4-chloropyridin-2-yl)amino]piperidine-1-carboxylate …

ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE

Experimental
Matched Name: … ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE …
Matched Iupac: … ethyl 4-[(4-methylpyridin-2-yl)amino]piperidine-1-carboxylate …

(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID

Experimental
Matched Name: … (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID …
Matched Iupac: … 2-[2-(carbamoylmethyl)-5-propyl-1H-indol-7-yl]acetic acid …

Polyacrylamide (crosslinked; 2 mole percent bisacrylamide)

Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females).
Investigational
Matched Name: … Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) …
Matched Description: … Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 …

Remogliflozin etabonate

Remogliflozin etabonate has been used in trials studying the treatment and basic science of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … }-1H-pyrazol-3-yl]oxy}oxan-2-yl]methyl carbonate ... ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{[5-methyl-1-(propan-2-yl)-4-{[4-(propan-2-yloxy)phenyl]methyl …
Matched Description: … Mellitus and Diabetes Mellitus, Type 2. ... Remogliflozin etabonate has been used in trials studying the treatment and basic science of Type 2 Diabetes …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …

5-Bromo-N[2-(Dimethylamino)Ethyl]-9-Aminoacridine-4-Carboxamide

Experimental
Matched Name: … 5-Bromo-N[2-(Dimethylamino)Ethyl]-9-Aminoacridine-4-Carboxamide …
Matched Iupac: … 9-amino-4-bromo-5-{[2-(dimethylazaniumyl)ethyl]carbamoyl}acridin-10-ium …

N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-2-Methyl-Butane

Experimental
Matched Name: … N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-2-Methyl-Butane …
Matched Iupac: … (3S)-3-hydroxy-3-{[(1S)-3-methyl-1-[(3-methylbutyl)carbamoyl]butyl]carbamoyl}propanoic acid …

4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID

Experimental

OTL-102

OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational

N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine

Experimental
Matched Iupac: … -dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide ... N-[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4R,5R,6R)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-4,5 …

4-Methoxy-E-Rhodomycin T

Experimental
Matched Iupac: … methyl (1R,2R,4S)-4-{[(2R,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-2,5,12 …
Displaying drugs 9376 - 9400 of 9650 in total