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Displaying drugs 9476 - 9500 of 10056 in total

2-(Trimethylammonium)Ethyl Thiol

Experimental
Matched Name: … 2-(Trimethylammonium)Ethyl Thiol …
Matched Iupac: … trimethyl(2-sulfanylethyl)azanium …

L-2-Amino-6-Methylene-Pimelic Acid

Experimental
Matched Name: … L-2-Amino-6-Methylene-Pimelic Acid …
Matched Iupac: … (2S)-2-amino-6-methylideneheptanedioic acid …

2'-Deoxy-thymidine-beta-L-rhamnose

Experimental
Matched Name: … 2'-Deoxy-thymidine-beta-L-rhamnose …
Matched Iupac: … -5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinic acid ... {[hydroxy({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy})phosphoryl]oxy}({[(2R,3S,5R)-3-hydroxy …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE

Experimental
Matched Name: … N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE …
Matched Iupac: … 4-chloro-N-(2-hydroxyethyl)benzamide …

Cilomilast

Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. Following four clinical trials, the drug proved to be effective in treating COPD, however it...
Investigational
Matched Synonyms: … cis-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …

5-Hydroxy-N-Propargyl-1(R)-Aminoindan

Experimental
Matched Name: … 5-Hydroxy-N-Propargyl-1(R)-Aminoindan …
Matched Iupac: … (3R)-3-[(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-inden-5-ol …

4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN

Experimental
Matched Name: … 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN …
Matched Iupac: … (1R)-1-[(E)-(prop-2-en-1-ylidene)amino]-2,3-dihydro-1H-inden-4-ol …

6-hydroxymethylpterin diphosphate

Experimental
Matched Synonyms: … 2-Amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphate …
Matched Iupac: … ({[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Sodium dichloroacetate

Investigational

Dethiobiotin

Experimental
Matched Synonyms: … (4R-cis)-5-methyl-2-oxo-4-imidazolidinehexanoic acid ... (4R,5S)-5-methyl-2-oxo-4-imidazolidinehexanoic acid …
Matched Iupac: … 6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Sepetaprost

Sepetaprost has been used in trials studying the treatment of Open Angle-glaucoma, Ocular Hypertension, and Mild Open Angle-glaucoma (OAG).
Investigational
Matched Iupac: … propan-2-yl 4-[(3S,5aR,6R,7R,8aS)-6-[(1E,3R)-4-(2,5-difluorophenoxy)-3-hydroxybut-1-en-1-yl]-7-hydroxy-octahydro ... -2H-cyclopenta[b]oxepin-3-yl]butanoate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Loxicodegol

Loxicodegol was developed by Nektar Therapeutics as an opioid analgesic with low abuse potential for the treatment of chronic pain . The lack of abuse potential is believed to be due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid class...
Investigational
Matched Iupac: … hexaoxanonadecan-19-yloxy)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7( …

Ingenol disoxate

Ingenol disoxate is under investigation in clinical trial NCT02120456 (Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis).
Investigational
Matched Iupac: … (1S,4S,5S,6R,9S,10R,12R,14R)-5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[ …

1,8-Di-Hydroxy-4-Nitro-Anthraquinone

Experimental
Matched Iupac: … 4,5-dihydroxy-1-nitro-9,10-dihydroanthracene-9,10-dione …

humanized SMART Anti-IL-12 Antibody

The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational

1-[4-(hydroxymethyl)phenyl]guanidine

Experimental
Matched Name: … 1-[4-(hydroxymethyl)phenyl]guanidine …

Tesmilifene

Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.
Investigational
Matched Synonyms: … N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine …
Matched Iupac: … [2-(4-benzylphenoxy)ethyl]diethylamine …
Matched Salts cas: … 92981-78-7 …

H-89

Experimental
Matched Synonyms: … N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide …
Matched Iupac: … N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cobnabexagene anvuparvovec

Experimental

CTx-PDE6b

CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human PDE6b gene. Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to PDE6b gene mutations.
Investigational

(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID

Experimental
Matched Iupac: … N-{4-[2-(2-{[(tert-butoxy)carbonyl]amino}ethyl)-3-ethoxy-2-(ethoxycarbonyl)-3-oxopropyl]phenyl}sulfamic …

N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE

Experimental
Matched Name: … N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE …
Matched Iupac: … 5-chloro-N'-[2-(trifluoromethyl)benzenesulfonyl]-1-benzofuran-2-carbohydrazide …

N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE

Experimental
Matched Name: … N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE …
Matched Iupac: … (1r,4r)-N-{2'-[(4-fluorophenyl)amino]-[4,4'-bipyridin]-2-yl}-4-methoxycyclohexane-1-carboxamide …

Viral Macrophage-Inflammatory Protein

Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer under most conditions. It helps its virus evade the host immune system through selectively blocking and activating different receptors, preferentially...
Investigational

Siagoside

Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair. Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. Sygen appears to...
Investigational
Matched Iupac: … N-[(2S,3R,4E)-1-{[(2R,3R,4R,5S,6R)-5-[(2S,4S,4'aR,5R,5'S,6R,7'R,8'S,8'aS)-5-acetamido-8'-{[(2S,3R,4R, ... )oxan-2-yl]oxy}oxan-2-yl]oxy}-4-hydroxy-7'-(hydroxymethyl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-hexahydrospiro ... [oxane-2,2'-pyrano[3,4-b][1,4]dioxin]-3'-oneoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-hydroxyoctadec ... -4-en-2-yl]octadecanamide ... 5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl …
Matched Description: … Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. ... Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. …
Displaying drugs 9476 - 9500 of 10056 in total