Displaying drugs 951 - 975 of 1246 in total
Angiotensin II
Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.
As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … Human angiotensin II ... Angiotensin II (human) …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Nerve Tissue Proteins …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Nerve Tissue Proteins …
Avalotcagene ontaparvovec
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 encoding human ornithine transcarbamylase ... Recombinant adeno-associated virus serotype AAV8 vector encoding human ornithine transcarbamylase …
Recombinant human insulin-like growth factor 1
Investigational
Matched Name: … Recombinant human insulin-like growth factor 1 …
CT-001
Investigational
Matched Synonyms: … Human recombinant factor VIIa variant (P10Q, K32E, T106N, V253N), desialylated …
CR002
CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Spheramine
Investigational
Matched Synonyms: … Allogeneic human retinal pigment epithelial cells on gelatin microcarriers …
Gatipotuzumab
Gatipotuzumab is under investigation in clinical trial NCT01899599 (Pankomab-gex™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer).
Investigational
Matched Synonyms: … with human-mus musculus monoclonal pankomab-gex light chain, dimer ... Immunoglobulin g1, anti-(mucin muc1) (human-mus musculus monoclonal pankomab-gex heavy chain), disulfide …
CAN-106
CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5.
Investigational
Matched Synonyms: … disulfide with human monoclonal CAN106 Kappa-chain, dimer ... Immunoglobulin G [27-histidine,57-histidine,253-tyrosine,255- threonine,257-glutamic acid], anti-(human ... complement C5) (human monoclonal CAN106 hybrid y2-chain CH1-hinge region/y4-chain CH2- CH3 region), …
Matched Description: … CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5. …
Matched Description: … CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5. …
Ontamalimab
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
Matched Synonyms: … human IgG2 monoclonal antibody directed against the mucosal addressin cell adhesion molecule ... human IgG2 anti-monoclonal antibody directed against mucosal addressin cell adhesion molecule (MAdCAM …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Antithymocyte immunoglobulin (rabbit)
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Synonyms: … Rabbit anti-human thymocyte globulin ... Anti-human thymocyte immunoglobulin, rabbit ... Rabbit anti-human thymocyte immunoglobulin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Fluids and Secretions ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Fluids and Secretions ... Proteins ... Blood Proteins …
Pucotenlimab
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus ... musculus monoclonal hx008 .gamma.4-chain), disulfide with human-mus musculus monoclonal hx008 .kappa …
Ragifilimab
Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1 (de-448-lysine), anti-(human tumor necrosis factor receptor tnfrsf18) (human-mus musculus ... monoclonal incagn01876.gamma.1-chain), disulfide with human-mus musculus monoclonal incagn01876 .kappa …
Muplestim
Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia).
Investigational
Matched Synonyms: … Interleukin 3 (human) ... Human interleukin-3 (nonglycosylated) ... Interleukin-3 human (recombinant) …
Matched Description: … investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and ... Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Matched Description: … investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and ... Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Dilpacimab
Dilpacimab is under investigation in clinical trial NCT03368859 (A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab).
Investigational
Matched Synonyms: … heavy chain), disulfide with synthetic human pr-1283233 light chain, dimer ... Immunoglobulin, anti-(notch ligand dll4/vascular endothelial growth factor) (synthetic human pr-1283233 …
Matched Description: … in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Simlukafusp alfa
RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Synonyms: … Anti-fap/interleukin-2 fusion protein ro6874281 …
Gontivimab
Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection).
Investigational
Matched Synonyms: … Anti-rsv protein f nanobody alx-0171 …
Matched Description: … Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult ... Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult ... Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Giloralimab
Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cd40 antigen) (human-mus musculus monoclonal pr-1614645 .gamma.1-chain ... ), disulfide with human-mus musculus monoclonal pr-1614645 .kappa. …
Matched Description: … Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and …
Matched Description: … Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and …
ATYR-1940
Investigational
Matched Synonyms: … Human recombinant histidyl-t-RNA synthetase (residues 2-506) …
.gamma.-brain natriuretic peptide
Investigational
Matched Synonyms: … Natriuretic peptides b (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Nerve Tissue Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Nerve Tissue Proteins …
Human blood group H type 1 trisaccharide
Experimental
Matched Name: … Human blood group H type 1 trisaccharide …
Human autologous bone marrow derived osteoblastic cells
Investigational
Matched Name: … Human autologous bone marrow derived osteoblastic cells …
PRTX-100
PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a subset of B-cells that are involved in the development and progression of various autoimmune diseases. These binding interactions enable the compound to modulate the function of these cells and restore the balance of the...
Investigational
Matched Synonyms: … Staphylococcus aureus protein A …
Matched Description: … PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a ... subset of B-cells that are involved in the development and progression of various autoimmune diseases ... These binding interactions enable the compound to modulate the function of these cells and restore the …
Matched Description: … PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a ... subset of B-cells that are involved in the development and progression of various autoimmune diseases ... These binding interactions enable the compound to modulate the function of these cells and restore the …
Citatuzumab Bogatox
VB6-845 is a humanized antibody fragment targeting EpCAM fused with the deimmunized form of the cytotoxin Bouganin and is designed for systemic use against metastatic cancer. VB6-845 has demonstrated effective cancer cell killing properties in pre-clinical tests.
Investigational
Matched Synonyms: … ANTI-EPCAM ANTIBODY FRAGMENT-BOUGANIN FUSION PROTEIN …
Matched Description: … humanized antibody fragment targeting EpCAM fused with the deimmunized form of the cytotoxin Bouganin and …
Matched Description: … humanized antibody fragment targeting EpCAM fused with the deimmunized form of the cytotoxin Bouganin and …
Displaying drugs 951 - 975 of 1246 in total