Displaying drugs 9726 - 9750 of 14724 in total
Formononetin
Formononetin is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
Investigational
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
INO-4800
INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.[A214475, A214478] Follow up studies in both...
Investigational
Matched Description: … of INO-4800 to induce both humoral and T cell-mediated immunity against SARS-CoV-2, including in the ... [A214475, A214478] Follow up studies in both BALB/c mice and Hartley guinea pigs demonstrated the ability ... clinical trial through South Korea's Seoul National University Hospital was announced on June 4, 2020, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Phenserine
Phenserine is under development by Axonyx, a US biopharmaceutical company that focuses on treatments for dementia. Phenserine is a next generation acetylcholinesterase (AChE) inhibitor indicated for the treatment of AD. Unlike currently marketed AChE inhibitors, it has a dual mechanism of action that also includes anti-amyloid activity, which may confer...
Investigational
Lazertinib
Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Description: … Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
4-Deoxy-D-Mannuronic Acid
Experimental
(S)-2-Tetrahydrofuroic acid
Experimental
4-(METHYLSULFONYL)BENZENECARBOXIMIDAMIDE
Experimental
Bevasiranib
Bevasiranib is a small interfering RNA (siRNA) targeting vascular endothelial growth factor A (VEGF-A).
Investigational
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Roquinimex
Roquinimex is a derivative of quinoline that presents immunostimulant properties. Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity. Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha.
Investigational
Matched Description: … Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity. ... Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Eprotirome
Eprotirome which is a compound with promising properties for treatment of obesity and dyslipidemia. Eprotirome increases the body’s energy consumption and reduces body weight and markedly reduces blood lipids and blood glucose.
Investigational
Matched Description: … lipids and blood glucose. ... Eprotirome increases the body’s energy consumption and reduces body weight and markedly reduces blood ... Eprotirome which is a compound with promising properties for treatment of obesity and dyslipidemia. …
Benzquinamide
Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
Withdrawn
Matched Description: … Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative ... is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and …
2-deoxy-2-acetamido-beta-D-galactose-4-sulfate
Experimental
K201 free base
Experimental
Investigational
Methylumbelliferyl chitotriose
Experimental
VX-702
VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Displaying drugs 9726 - 9750 of 14724 in total