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Displaying drugs 9801 - 9825 of 10992 in total
Tebipenem pivoxil
Investigational
Matched Iupac: … [(4R,5S,6S)-3-{[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl ... -7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carbonyloxy]methyl 2,2-dimethylpropanoate …
JAK4D
JAK4D is a first-in-class thyrotropin-releasing hormone (TRH)-based compound.
Investigational
Matched Iupac: … (3S)-4-[(2S)-2-{[(1R)-1-{[(1R)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl ... ]carbamoyl}pyrrolidin-1-yl]-4-oxo-3-{[(2S)-5-oxopyrrolidin-2-yl]formamido}butanamide …
Zosuquidar
Zosuquidar is a compound of antineoplastic drug candidates currently under development. It is now in "Phase 3" of clinical tests in the United States. Its action mechanism consists of the inhibition of P-glycoproteins; other drugs with this mechanism include tariquidar and laniquidar.
Investigational
Matched Iupac: … (2R)-1-{4-[(2R,4S,11R)-3,3-difluorotetracyclo[10.4.0.0^{2,4}.0^{5,10}]hexadeca-1(16),5,7,9,12,14-hexaen ... -11-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol …
Cefalonium
Experimental
Vet approved
Matched Iupac: … 4-carbamoyl-1-{[(6R,7R)-2-carboxylato-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0] ... oct-2-en-3-yl]methyl}pyridin-1-ium …
Deleobuvir
Deleobuvir is under investigation in clinical trial NCT01983566 (Effect of Food and Increased Gastric pH Value on Bioavailability of a Single Dose of BI 207127 in Healthy Caucasian and Japanese Subjects).
Investigational
Matched Iupac: … (2E)-3-(2-{1-[2-(5-bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-amido]cyclobutyl}-1-methyl …
2-amino-3-[4-hydroxy-6-oxo-3-(2-phenyl-cyclopropylimino)-cyclohexa-1,4-dienyl]-propionic acid
Experimental
Matched Iupac: … 2-amino-3-[(5E)-4-hydroxy-2-oxo-5-[(2-phenylcyclopropyl)imino]cyclohex-3-en-1-yl]propanoic acid …
Garenoxacin
Garenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Investigational
Matched Iupac: … 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline …
Fosdevirine
Investigational
Matched Iupac: … (S)-(methyl (2-carbamoyl-5-chloro-1H-indol-3-yl)({3-[(1E)-2-cyanoeth-1-en-1-yl]-5-methylphenyl})phosphinate …
Clocapramine
Clocapramine is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 for the treatment of schizophrenia. In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic. Clocapramine has been implicated in at least one strange death,...
Experimental
Matched Iupac: … 1'-(3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)-[1,4'-bipiperidine …
Eltanolone
Eltanolone is under investigation in clinical trial NCT02603926 (Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone).
Investigational
Matched Iupac: … ]ethan-1-one ... 1-[(1S,2S,5R,7R,10R,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl …
CHF-6001
CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … ium-1-olate ... )-4-(difluoromethoxy)phenyl]-2-[3-(cyclopropylmethoxy)-4-methanesulfonamidobenzoyloxy]ethyl]pyridin-1- …
Chlorfenson
Chlorfenson is developed by Moberg Derma for the treatment of onychomycosis (nail fungus) as the primary indication.
Investigational
Matched Iupac: … 4-chlorophenyl 4-chlorobenzene-1-sulfonate …
N-chlorotaurine
N-chlorotaurine is an inhibitor of inducible nitric oxide synthase and IkappaB kinase.
Investigational
Matched Iupac: … 2-(chloroamino)ethane-1-sulfonic acid …
N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide
Experimental
Matched Iupac: … 1-carbamimidamido-N-(3,5-dimethoxyphenyl)methanimidamide …
Cyclopentamine
Cyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia. It has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine.
Withdrawn
Matched Iupac: … (1-cyclopentylpropan-2-yl)(methyl)amine …
Butonate
Experimental
Vet approved
Matched Iupac: … 2,2,2-trichloro-1-(dimethoxyphosphoryl)ethyl butanoate …
Displaying drugs 9801 - 9825 of 10992 in total