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Displaying drugs 9876 - 9900 of 11684 in total
Leptin
Although leptin is a circulating signal that reduces appetite, in general, obese people have an unusually high circulating concentration of leptin. These people are said to be resistant to the effects of leptin, in much the same way that people with type 2 diabetes are resistant to the effects of...
Investigational
Matched Description: … people are said to be resistant to the effects of leptin, in much the same way that people with type 2 …
6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine
Experimental
Matched Name: … 6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine …
Matched Iupac: … 6-carbamimidoyl-N-phenylnaphthalene-2-carboxamide …
Matched Iupac: … 6-carbamimidoyl-N-phenylnaphthalene-2-carboxamide …
(S)-2-(Phosphonoxy)Caproyl-L-Leucyl-P-Nitroanilide
Experimental
Matched Name: … (S)-2-(Phosphonoxy)Caproyl-L-Leucyl-P-Nitroanilide …
Matched Iupac: … {[(1S)-1-{[(1S)-3-methyl-1-[(4-nitrophenyl)carbamoyl]butyl]carbamoyl}pentyl]oxy}phosphonic acid …
Matched Iupac: … {[(1S)-1-{[(1S)-3-methyl-1-[(4-nitrophenyl)carbamoyl]butyl]carbamoyl}pentyl]oxy}phosphonic acid …
gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine
Experimental
Matched Name: … gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2-iodophenyl)methyl]sulfanyl}ethyl]carbamoyl} …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2-iodophenyl)methyl]sulfanyl}ethyl]carbamoyl} …
Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate
Experimental
Matched Name: … Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate …
Matched Iupac: … tert-butyl N-[(1S)-1-cyclohexyl-2-oxoethyl]carbamate …
Matched Iupac: … tert-butyl N-[(1S)-1-cyclohexyl-2-oxoethyl]carbamate …
N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide
Experimental
Matched Name: … N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide …
Matched Iupac: … 2-{[1,1'-biphenyl]-4-sulfonamido}-N-oxoacetamide …
Matched Iupac: … 2-{[1,1'-biphenyl]-4-sulfonamido}-N-oxoacetamide …
(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE
Experimental
Matched Name: … (1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE …
Matched Iupac: … 1-(3-carboximidoylbut-3-en-1-yl)-4-fluorobenzene …
Matched Iupac: … 1-(3-carboximidoylbut-3-en-1-yl)-4-fluorobenzene …
Simtuzumab
Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.
Investigational
PMC-403
PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Niceritrol
Experimental
Matched Iupac: … 3-(pyridine-3-carbonyloxy)-2,2-bis[(pyridine-3-carbonyloxy)methyl]propyl pyridine-3-carboxylate …
PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE
Experimental
Matched Name: … PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE …
Matched Iupac: … (2S)-N-tert-butylpiperidine-2-carboxamide …
Matched Iupac: … (2S)-N-tert-butylpiperidine-2-carboxamide …
TAK-448
TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
Investigational
Matched Iupac: … }-2-hydroxypropyl]-2-{[(2S,4R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxypyrrolidin- ... (2S)-N-[(1S,2R)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}-4 ... -(N'-methylcarbamimidamido)butyl]carbamoyl}-3-methylbutyl]carbamoyl}amino)carbamoyl]-2-phenylethyl]carbamoyl ... 2-yl]formamido}butanediamide …
WRR-99
Experimental
Matched Iupac: … (3S)-3-hydroxy-3-{[(1R)-1-[(3-methylbutyl)carbamoyl]-3-phenylpropyl]carbamoyl}propanoic acid …
AZD-7762
AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Investigational
Matched Iupac: … 3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide …
Carlumab
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Simlukafusp alfa
RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Synonyms: … Anti-fap/interleukin-2 fusion protein ro6874281 …
alpha-N-Acetyl-D-galactosamine
The N-acetyl derivative of galactosamine. [PubChem]
Experimental
Investigational
Matched Synonyms: … N-acetyl-2-deoxy-2-amino-galactose …
Matched Iupac: … N-[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide …
Matched Iupac: … N-[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide …
Zinpentraxin alfa
Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Investigational
Matched Synonyms: … rhPTX-2 ... Recombinant human pentraxin-2 …
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. ... It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With …
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. ... It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With …
Ontamalimab
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
NGN-401
NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2). Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
Investigational
Matched Synonyms: … sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 …
Matched Description: … sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 …
Matched Description: … sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 …
Pelacarsen
Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease).
Investigational
Matched Description: … Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo …
Alnuctamab
Investigational
Nisoxetine
Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. It was originally investigated as an antidepressant but has no current clinical applications aside from being a research standard SNRI. It has been used to research obesity and energy balance, and exerts some local analgesia effects.
Experimental
Matched Iupac: … [3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine …
Methylmethionine chloride
Methylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support. It is also called "Vitamin U", but it is not a true vitamin.
Experimental
Matched Iupac: … [(3S)-3-amino-3-carboxypropyl]dimethylsulfanium chloride …
Displaying drugs 9876 - 9900 of 11684 in total