Displaying drugs 9926 - 9950 of 11094 in total
Odalasvir
Odalasvir has been used in trials studying the treatment of Hepatitis C, Chronic and Chronic Hepatitis C Infection.
Investigational
Matched Iupac: … methyl N-[(2S)-1-[(2S,3aS,7aS)-2-[6-(14-{2-[(2S,3aS,7aS)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl ... ),10,13-hexaen-5-yl)-1H-1,3-benzodiazol-2-yl]-octahydro-1H-indol-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate ... ]-octahydro-1H-indol-2-yl]-1H-1,3-benzodiazol-6-yl}tricyclo[8.2.2.2^{4,7}]hexadeca-1(12),4(16),5,7(15 …
Temafloxacin
Temafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class. It was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three deaths.
Withdrawn
Matched Iupac: … 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
ACV tripeptide
Experimental
Matched Iupac: … (2S)-2-amino-5-{[(1R)-1-{[(1R)-1-carboxy-2-methylpropyl]carbamoyl}-2-sulfanylethyl]carbamoyl}pentanoic …
S-azabisabolene
Experimental
Matched Iupac: … (R,1R)-N,4-dimethyl-N-(4-methylpent-3-en-1-yl)cyclohex-3-en-1-aminium …
Allyl-{6-[3-(4-Bromo-Phenyl)-Benzofuran-6-Yloxy]-Hexyl-}-Methyl-Amin
Experimental
Matched Iupac: … (6-{[3-(4-bromophenyl)-1-benzofuran-6-yl]oxy}hexyl)(methyl)(prop-2-en-1-yl)amine …
Oseltamivir acid
Experimental
Matched Iupac: … (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid …
4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide
Experimental
Matched Iupac: … 4-[(1E)-2-(5-bromo-2-oxo-2H-indol-3-yl)diazen-1-yl]benzene-1-sulfonamide …
Fleroxacin
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Fleroxacin is not an inhibitor of CYP1A2.
Experimental
Matched Iupac: … 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Difloxacin
Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials.
Vet approved
Matched Iupac: … 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Atreleuton
Atreleuton has been used in trials studying the treatment of Atherosclerosis and Coronary Artery Disease.
Investigational
Matched Iupac: … 1-[(2R)-4-{5-[(4-fluorophenyl)methyl]thiophen-2-yl}but-3-yn-2-yl]-1-hydroxyurea …
Pinazepam
Experimental
Matched Iupac: … 7-chloro-5-phenyl-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
M-2698
M-2698 is under investigation in clinical trial NCT01971515 (First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies).
Investigational
Matched Iupac: … 4-{[(1S)-2-(azetidin-1-yl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl]amino}quinazoline-8-carboxamide …
OTX-008
OTX008 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Iupac: … {9,13}.1^{15,19}]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaen-25-yl]oxy}acetamide ... dimethylamino)ethyl]-2-{[26,27,28-tris({[2-(dimethylamino)ethyl]carbamoyl}methoxy)pentacyclo[19.3.1.1^{3,7}.1^ …
Tebipenem pivoxil
Investigational
Matched Iupac: … [(4R,5S,6S)-3-{[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl ... -7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carbonyloxy]methyl 2,2-dimethylpropanoate …
JAK4D
JAK4D is a first-in-class thyrotropin-releasing hormone (TRH)-based compound.
Investigational
Matched Iupac: … (3S)-4-[(2S)-2-{[(1R)-1-{[(1R)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl ... ]carbamoyl}pyrrolidin-1-yl]-4-oxo-3-{[(2S)-5-oxopyrrolidin-2-yl]formamido}butanamide …
Tenamfetamine
An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally. [PubChem]
Experimental
Illicit
Matched Iupac: … 1-(2H-1,3-benzodioxol-5-yl)propan-2-amine …
4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide
Experimental
Matched Iupac: … 4-[(6-aminopyrimidin-4-yl)amino]benzene-1-sulfonamide …
Perifosine
Perifosine is a novel alkylphospholipid with antiproliferative properties attributed to protein kinase B inhibition.
Investigational
Matched Iupac: … 1,1-dimethyl-4-{[(octadecyloxy)phosphinato]oxy}piperidin-1-ium …
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
Experimental
Matched Iupac: … [(1S,3R,7R)-1-hydroxy-3,7,11-trimethyldodecyl]phosphonic acid …
Sulfaquinoxaline
Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as potential treatment of coccidiosis.
Vet approved
Matched Iupac: … 4-amino-N-(quinoxalin-2-yl)benzene-1-sulfonamide …
Atagabalin
Atagabalin has been used in trials studying the treatment of Insomnia, Primary Insomnia, and Nonrestorative Sleep.
Investigational
Matched Iupac: … 2-[(3S,4S)-1-(aminomethyl)-3,4-dimethylcyclopentyl]acetic acid …
Dasotraline
Dasotraline is a serotonin, norepinephrine and dopamine reuptake inhibitor (SNDRI) that is under investigation for the treatment of Binge Eating Disorder, Adult Attention Hyperactivity Disorder, Attention Deficit Hyperactivity Disorder, and Adult Attention Deficit Hyperactivity Disorder.
Investigational
Matched Iupac: … (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine …
Desmethylsertraline
Desmethylsertraline is a metabolite of sertraline.
Experimental
Matched Iupac: … (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine …
Displaying drugs 9926 - 9950 of 11094 in total