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Displaying drugs 10051 - 10075 of 11673 in total
GSK2256098 is under investigation in clinical trial NCT02523014 (Vismodegib and FAK Inhibitor GSK2256098 in Treating Patients With Progressive Meningiomas).
Investigational
Matched Iupac: … 2-[(5-chloro-2-{[3-methyl-1-(propan-2-yl)-1H-pyrazol-5-yl]amino}pyridin-4-yl)amino]-N-methoxybenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Synonyms: … D-Mannose 1-phosphate ... Mannose 1-phosphate ... D-mannose 1-phosphates …
Matched Name: … D-Mannose 1-phosphate …
Matched Iupac: … {[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid …
GPX-100 is an anthracycline anticancer drug that belongs to the family of drugs called antitumor antibiotics.
Investigational
Matched Iupac: … (8R,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyethyl ... )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione …
Investigational
Matched Iupac: … 4-{2-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl} …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lisavanbulin is under investigation in clinical trial NCT02895360 (Phase 1/2a Study of BAL101553 as 48-hour Infusions in Patients With Advanced Solid Tumors or Recurrent Glioblastoma).
Investigational
Matched Iupac: … (2S)-2,6-diamino-N-{4-[2-(2-{4-[(2-cyanoethyl)amino]-1,2,5-oxadiazol-3-yl}-1H-1,3-benzodiazol-1-yl)acetyl …
Matched Description: … Lisavanbulin is under investigation in clinical trial NCT02895360 (Phase 1/2a Study of BAL101553 as 48 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Razuprotafib, also known as AKB-9778, is a small-molecule inhibitor restoring Tie2 activation by inhibiting VE-PTP.[L27171,L27176] In investigations against diabetes and COVID-19, razuprotafib is self-administered by patients through subcutaneous injection.
Investigational
Matched Iupac: … N-{4-[(2S)-2-[(2S)-2-[(methoxycarbonyl)amino]-3-phenylpropanamido]-2-[2-(thiophen-2-yl)-1,3-thiazol-4 …
Experimental
Experimental
Matched Name: … 1-Butane Boronic Acid …
Experimental
Matched Iupac: … 5-hydroxy-6-[(E)-2-(2-hydroxy-5-sulfophenyl)diazen-1-yl]-2-{[4-({5-hydroxy-6-[(E)-2-(2-hydroxy-5-sulfophenyl ... )diazen-1-yl]-1,7-disulfonaphthalen-2-yl}amino)-1,3,5-triazin-2-yl]amino}naphthalene-1,7-disulfonic acid …
Investigational
Matched Iupac: … tetrasodium 8-amino-2-[(E)-2-{4'-[(E)-2-(8-amino-1-oxido-7-sulfo-5-sulfonatonaphthalen-2-yl)diazen-1- ... yl]-3,3'-dimethyl-[1,1'-biphenyl]-4-yl}diazen-1-yl]-7-sulfo-5-sulfonatonaphthalen-1-olate …
Experimental
Matched Synonyms: … 2-Aminopimelic acid ... (2S)-2-Aminoheptanedioic acid ... (S)-2-aminoheptanedioic acid …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery.
Investigational
Matched Synonyms: … (4R)-1-methyl-4-isopropenylcyclohex-1-ene ... (R)-4-isopropenyl-1-methyl-1-cyclohexene ... (R)-1-methyl-4-(1-methylethenyl)cyclohexene …
Matched Iupac: … (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene …
Experimental
Matched Synonyms: … Calcium (2+) ... calcium(2+) ion ... Calcium(2+)ions …
Matched Iupac: … calcium(2+) ion …
Experimental
Matched Synonyms: … (2s)-2-Hydroxypropanal ... L-2-Hydroxypropionaldehyde …
Matched Iupac: … (2S)-2-hydroxypropanal …
Danoprevir has been used in trials studying the treatment of Hepatitis C, Chronic.
Investigational
Matched Iupac: … -dihydro-1H-isoindole-2-carboxylate ... cyclopropanesulfonyl)carbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadec-7-en-18-yl 4-fluoro-2,3
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Norvaline is an isomer of the more common amino acid valine.
Experimental
Matched Synonyms: … 2-Aminovaleric acid ... 2-Aminopentanoic acid ... L-2-Aminovaleric acid …
Matched Iupac: … (2S)-2-aminopentanoic acid …
Investigational
Experimental
Taberminogene vadenovec (EG004) is a novel product consisting of a local delivery device and a gene-based medicine, being developed to prevent the blocking of veins and arteries that frequently occurs after vascular surgery. The initial target market is haemodialysis graft access surgery, a procedure in which patients whose kidneys have...
Investigational
Experimental
Matched Name: … 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine …
Matched Iupac: … ({[(2S)-1-(2,6-diamino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate …
According to Zymeworks, "ZW49 (zanidatamab zovodotin) is a bispecific anti-HER2 ADC that is based on the same antibody framework as ZW25 but armed with a cytotoxic payload." It is being investigated for several indications characterized by HER2 expression including breast and gastric cancers that have progressed or are refractory to...
Investigational
Experimental
Matched Name: … TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE …
Experimental
Matched Name: … 2-Ethylhexyl 4-phenylbenzophenone-2'-carboxylate …
Matched Iupac: … 2-ethylhexyl 2-{[1,1'-biphenyl]-4-carbonyl}benzoate …
Experimental
Displaying drugs 10051 - 10075 of 11673 in total