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Displaying drugs 1001 - 1025 of 1158 in total

AMT-130

Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 5 encoding a microRNA targeted to human Huntingtin gene …

CypCaps

Investigational
Matched Synonyms: … Cytochrome P450 isoform 2B1 gene transfected human embryonic kidney 293 cells encapsulated in polymeric …

Sulanemadlin

Investigational
Matched Synonyms: … N-acetyl-l-leucyl-l-threonyl-l-phenylalanyl-cyclo(d-r8-l-glutamyl-ltyrosyl-ltryptophanyl-l-alanyl-l-glutaminyl-l-leucyl-l-s5 …

Eflepedocokin alfa

Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Synonyms: … RECOMBINANT HUMAN INTERLEUKIN-22 IGG2-FC ... F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO …
Matched Description: … recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

AGIL-FA

Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein …

PR1 leukemia peptide vaccine

PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … L-VALINE, L-VALYL-L-LEUCYL-L-GLUTAMINYL-L-.ALPHA. …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …

Tralesinidase alfa

Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Recombinant human NAGLU-insulin-like growth factor II ... Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2 …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …

Pegvorhyaluronidase alfa

Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … PEGylated recombinant human hyaluronidase PH20 ... -METHOXY-, AMIDE WITH HYALURONOGLUCOSAMINIDASE (HUMAN ISOENZYME PH20) ... HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And …
Matched Categories: … Enzymes and Coenzymes …

Obexelimab

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human CD19 antigen) (human-mus musculus monoclonal XMAB5871 heavy chain), disulfide ... with human-mus musculus monoclonal XMAB5871 light chain, dimer …

Efungumab

Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(candida heat-shock protein hsp 90) (human monoclonal hsp90mab fragment) …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins …

NFS-02

NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene (rAAV2-ND1).
Investigational
Matched Synonyms: … recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene …
Matched Description: … NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized …

GYM329

GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …

Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen

Approved
Investigational
Matched Name: … Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen …

Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells

ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. These cells are...
Investigational
Matched Synonyms: … Allogeneic donor CD362 enriched human umbilical cord-derived mesenchymal stromal cells …
Matched Name: … Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells …
Matched Description: … The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one ... mesenchymal stem cells (UC-MSCs); UC-MSCs share stemness markers with both embryonic stem cells (ESCs) and ... adult mesenchymal stem cells (MSCs); this feature allows them to be hypoimmunogenic and non-inducible …

Ex vivo expanded autologous human corneal epithelial cells containing stem cells

Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.
Investigational
Matched Name: … Ex vivo expanded autologous human corneal epithelial cells containing stem cells …
Matched Description: … Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem …

Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen

Approved
Investigational
Matched Name: … Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen …

Rozrolimupab

Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and the prevention of Hemolytic Disease of Newborns (HDN).
Investigational
Matched Synonyms: … Recombinant human antigen-specific polyclonal antibody (pAb) against RhD antigen expressed in Chinese …
Matched Description: … anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

AAV-AIPL

AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human AIPL1 gene. Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in AIPL1 gene.
Investigational
Matched Synonyms: … adenovirus associated viral vector serotype 8 containing the human AIPL1 gene …
Matched Description: … AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. …

PTR-01

Investigational
Matched Synonyms: … Recombinant human collagen alpha-1 (VII) chain homo-trimer (rC7) …

PBFT02

PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding the protein progranulin.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding …
Matched Description: … PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN …

RR001

RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational
Matched Synonyms: … autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …

Mubodina

Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 …
Matched Description: … It was investigated in various conditions including primary membranoproliferative glomerulonephritis and ... It is a recombinant human minibody directed against complement component C5. …

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [clotrimazole], due to its broad spectrum and good absorption. ... synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and …
Matched Mixtures name: … SPORUM-D …
Matched Categories: … Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … SPOREX ... SPORUM® CASP 2% CHAMPU …

Anti-SARS-CoV-2 immunoglobulin

Hyperimmune immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and develop neutralizing antibodies. Anti-coronavirus immunoglobulin is derived from COVID-19 convalescent plasma(https://go.drugbank.com/drugs/DB15692) but contains more SARS-CoV-2 neutralizing antibodies than found in convalescent plasma (https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and concentrated.[L27521, L27526]
Investigational
Matched Synonyms: … Anti-COVID-19 hyperimmune globulin (human) ... Human plasma-derived immune-globulin for Coronavirus …
Matched Description: … immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and ... [convalescent plasma](https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … ADRONAT …
Displaying drugs 1001 - 1025 of 1158 in total