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Displaying drugs 10351 - 10375 of 12121 in total

6-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINE

Experimental
Matched Name: … 6-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINE …
Matched Iupac: … (6R)-6-[(1R,2S)-2-hydroxycyclopentyl]-7-oxoheptanimidamide …

KRN-7000

KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With Hematological Malignancies Undergoing AHSCT.
Investigational
Matched Synonyms: … 1-O-(α-D-galactopyranosyl)-N-hexacosanoylphytosphingosine …
Matched Iupac: … N-[(2S,3S,4R)-3,4-dihydroxy-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}octadecan ... -2-yl]hexacosanamide …

(S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID

Experimental
Matched Name: … (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID …
Matched Iupac: … (2S)-5-phenyl-2-(sulfanylmethyl)pentanoic acid …

Cobnabexagene anvuparvovec

Experimental

CTx-PDE6b

CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human PDE6b gene. Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to PDE6b gene mutations.
Investigational

Mercaptoethanol

Experimental
Matched Synonyms: … 2-mercaptoethanol …
Matched Iupac: … 2-sulfanylethan-1-ol …

INM004

INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Anti-Shiga toxin hyperimmune equine immunoglobulin F(ab')2 fragment ... Neutralizing equine anti-Stx hyperimmune immunoglobulin F(ab')2 fragment …
Matched Description: … INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being …

5-hydroxyvaleric acid

Experimental
Matched Synonyms: … 4-oxy-butan-carbonsäure …

6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL

Experimental
Matched Name: … 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL …
Matched Iupac: … 6-benzyl-1-[(benzyloxy)methyl]-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …

Ifenprodil

N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding...
Investigational
Withdrawn
Matched Iupac: … 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol …
Matched Description: … Ifenprodil is being investigated for its potential utility in treating COVID-19 in an ongoing phase 2b/3 …
Matched Salts cas: … 23210-58-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

7-methyl-guanosine-5'-triphosphate

Experimental
Matched Synonyms: … 7-methyl-GTP(1+) …
Matched Iupac: … ]oxy}methyl)oxolan-2-yl]-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium ... 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-({[hydroxy({[hydroxy(phosphonooxy)phosphoryl]oxy})phosphoryl …

Pyrrolidine

Investigational
Matched Synonyms: … 1-Azacyclopentane …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Modified vaccinia virus Ankara-85A antigen

Modified vaccinia virus Ankara-85A antigen is under investigation in clinical trial NCT00953927 (A Study of MVA85A in Healthy Infants).
Investigational

5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine

Experimental
Matched Name: … 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-8-ethenyl-9H-purin-9-yl)-5-({[4-(aminooxy)butyl](methyl)amino}methyl)oxolane …

Barnidipine

Barnidipine is a long-acting novel calcium antagonist that belongs to the dihydropyridine (DHP) group of calcium channel blockers. Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the smooth muscle cells in the vascular wall and selectivity against cardiovascular L-type calcium channels . Barnidipine...
Experimental
Matched Iupac: … 3-(3S)-1-benzylpyrrolidin-3-yl 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … The active component is composed of a single optical isomer (*3'S, 4S* configuration), which is the most ... year and 2-year follow-up period in 91% of the patients who had an initial response to the drug [A7842 ... moderate hypertension, the antihypertensive response from barnidipine treatment was maintained after a 1- …
Matched Salts cas: … 104757-53-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Siagoside

Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair. Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. Sygen appears to...
Investigational
Matched Iupac: … N-[(2S,3R,4E)-1-{[(2R,3R,4R,5S,6R)-5-[(2S,4S,4'aR,5R,5'S,6R,7'R,8'S,8'aS)-5-acetamido-8'-{[(2S,3R,4R, ... -4-en-2-yl]octadecanamide ... [oxane-2,2'-pyrano[3,4-b][1,4]dioxin]-3'-oneoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-hydroxyoctadec ... )oxan-2-yl]oxy}oxan-2-yl]oxy}-4-hydroxy-7'-(hydroxymethyl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-hexahydrospiro ... 5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl …
Matched Description: … Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. ... Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. …

Cuprous chloride

Experimental
Matched Synonyms: … Copper(1+) chloride …

Empegfilgrastim

Empegfilgrastim is under investigation in clinical trial NCT01569087 (Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer).
Investigational

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational

Sodium dichloroacetate

Investigational

9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine

Experimental
Matched Name: … 9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …

2'deoxy-Thymidine-5'-Diphospho-Alpha-D-Glucose

Experimental
Matched Name: … 2'deoxy-Thymidine-5'-Diphospho-Alpha-D-Glucose …
Matched Iupac: … ,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinic ... {[hydroxy({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})phosphoryl]oxy}({[(2R,3S …

Open Form of 2'-Deoxy-Ribofuranose-5'-Phosphate

Experimental
Matched Name: … Open Form of 2'-Deoxy-Ribofuranose-5'-Phosphate …

N-acetyl-L-arginine

Experimental
Matched Iupac: … (2S)-5-carbamimidamido-2-acetamidopentanoic acid …

Binodenoson

Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor. This specificity allows Binodenoson to deliver - in a single injection - a more effective dose of medication with fewer side effects than current treatments, which typically require a...
Investigational
Matched Synonyms: … 2-((Cyclohexylmethylene)hydrazino)adenosine …
Matched Iupac: … (2R,3R,4S,5R)-2-{6-amino-2-[(2E)-2-(cyclohexylmethylidene)hydrazin-1-yl]-9H-purin-9-yl}-5-(hydroxymethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 10351 - 10375 of 12121 in total