Displaying drugs 10376 - 10400 of 12433 in total
Epafipase
Epafipase is under investigation in clinical trial NCT00037687 (Safety and Efficacy of Recombinant Human Platelet-activating Factor Acetylhydrolase for the Treatment of Severe Sepsis).
Investigational
Matched Description: … Platelet-activating Factor Acetylhydrolase for the Treatment of Severe Sepsis). ... Epafipase is under investigation in clinical trial NCT00037687 (Safety and Efficacy of Recombinant Human …
L-3972-T
L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
GZ-389988
GZ-389988 is under investigation in clinical trial NCT02845271 (Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients With Painful Osteoarthritis of the Knee).
Investigational
Matched Description: … Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients ... With Painful Osteoarthritis of the Knee). ... GZ-389988 is under investigation in clinical trial NCT02845271 (Proof-of-concept Study to Assess the …
Peldesine
Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
Investigational
Matched Description: … Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. ... It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections. …
SL017
SL017 formulated as a topical gel, has been combined with a widely available light source for permanent removal of unwanted hair and for treatment of actinic keratosis
Investigational
Matched Description: … unwanted hair and for treatment of actinic keratosis ... formulated as a topical gel, has been combined with a widely available light source for permanent removal of …
Levilimab
Levilimab is under investigation in clinical trial NCT04227366 (Study of the Efficacy and Safety of BCD-089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis).
Investigational
Matched Description: … Levilimab is under investigation in clinical trial NCT04227366 (Study of the Efficacy and Safety of BCD …
VaxSyn
VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the National Institute of Allergy and Infectious Diseases (NIAID).
Investigational
Matched Description: … National Institute of Allergy and Infectious Diseases (NIAID). ... VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the …
N4-Hydroxycytidine
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Description: … activity against the coronavirus family of viruses. ... new virions, resulting in the accumulation of inactivating mutations. ... A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of …
Benzimate
Benzimate is the lead compound selected from a series of compounds known as benzimidazoles. The anti-cancer and anti-viral activity of the benzimidazoles was originally investigated by the Proctor & Gamble Company beginning in the 1990's. It is currently under investigation by AmpliMed and is in phase I of clinical trial.
Investigational
Matched Description: … Benzimate is the lead compound selected from a series of compounds known as benzimidazoles. ... It is currently under investigation by AmpliMed and is in phase I of clinical trial. ... The anti-cancer and anti-viral activity of the benzimidazoles was originally investigated by the Proctor …
Cyclomethicone 5
Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a...
Experimental
Matched Description: … Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have ... Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded …
ACE393
ACE393 is an injectable vaccine designed to combat the bacterium Campylobacter jejuni, one of the greatest causes of bacterial diarrhoeal infections in the developed world.
Investigational
Matched Description: … causes of bacterial diarrhoeal infections in the developed world. ... ACE393 is an injectable vaccine designed to combat the bacterium Campylobacter jejuni, one of the greatest …
Cetilistat
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
Investigational
Matched Description: … Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of …
ANA971
ANA971, an orally administered prodrug of isatoribine. Isatoribine is a nucleoside analog in development for the treatment of chronic hepatitis C virus (HCV) infection. ANA971 is a prodrug designed to improve the oral bioavailability of isatoribine. ANA971 resulted in higher levels of isatoribine in the blood than were present after...
Investigational
Matched Description: … of isatoribine itself. ... ANA971, an orally administered prodrug of isatoribine. ... ANA971 is a prodrug designed to improve the oral bioavailability of isatoribine. …
PRTX-100
PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a subset of B-cells that are involved in the development and progression of various autoimmune diseases. These binding interactions enable the compound to modulate the function of these cells and restore the balance of the...
Investigational
Matched Description: … balance of the immune system. ... subset of B-cells that are involved in the development and progression of various autoimmune diseases ... PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a …
BTA798
BTA798 is an antiviral for the treatment of HRV, the common cold virus, known to cause significant clinical complications in sufferers of Asthma and Chronic Obstructive Pulmonary Disease.
Investigational
Matched Description: … complications in sufferers of Asthma and Chronic Obstructive Pulmonary Disease. ... BTA798 is an antiviral for the treatment of HRV, the common cold virus, known to cause significant clinical …
WL-1002
WL-1002 is developed by Winston Laboratories which is a topical cream formulation of 075% zucapaicin (also known as civamide), for the treatment of pain due to osteoarthritis.
Investigational
Matched Description: … (also known as civamide), for the treatment of pain due to osteoarthritis. ... WL-1002 is developed by Winston Laboratories which is a topical cream formulation of 075% zucapaicin …
Contulakin-G
Contulakin-G is a broad spectrum non-opioid analgesic. It is the synthetic form of a natural peptide extracted from the venom of the Conus Geographus sea snail.
Investigational
Matched Description: … It is the synthetic form of a natural peptide extracted from the venom of the Conus Geographus sea snail …
PF-232798
PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
Investigational
Matched Description: … Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects). ... PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple …
Adagloxad simolenin
Adagloxad simolenin is under investigation in clinical trial NCT03562637 (Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC).
Investigational
Matched Description: … (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC). ... Adagloxad simolenin is under investigation in clinical trial NCT03562637 (Study of Adagloxad Simolenin …
Dapansutrile
Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee).
Investigational
Matched Description: … Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee). ... Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 …
Nadecnemab
Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee).
Investigational
Matched Description: … REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee). ... Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and Safety of …
BEA-17
BEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST. It is under investigation for the treatment of glioblastoma.
Investigational
Matched Description: … [L48330] It is under investigation for the treatment of glioblastoma. ... BEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST. …
TRX1
TRX1 is a humanized antibody that binds to the CD4 receptor found on a subset of T cells. TRX1 is being developed for the potential treatment of autoimmune diseases in collaboration with Genentech, Inc. TolerRx is currently conducting a Phase I clinical study of TRX1 in the United Kingdom.
Investigational
Matched Description: … TRX1 is a humanized antibody that binds to the CD4 receptor found on a subset of T cells. ... TolerRx is currently conducting a Phase I clinical study of TRX1 in the United Kingdom. ... TRX1 is being developed for the potential treatment of autoimmune diseases in collaboration with Genentech …
mRNA-3927
mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Matched Description: … mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and ... beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid ... Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.[L45998] …
Beclomethasone 17-monopropionate
An ester of beclomethasone.
Experimental
Matched Description: … An ester of beclomethasone. …
Displaying drugs 10376 - 10400 of 12433 in total