Displaying drugs 10426 - 10450 of 12433 in total
Veglin
VEGF-AS (Veglin) is an anti-angiogenesis non-chemotherapy drug (angiogenesis inhibitor) that was developed by VasGene Therapeutics, Inc. for the treatment of a variety of malignancies including mesothelioma. Veglin is one of several newly developed non-chemotherapy drugs being tested for possible utilization in the ongoing struggle to combat malignant mesothelioma.
Investigational
Matched Description: … a variety of malignancies including mesothelioma. ... Veglin is one of several newly developed non-chemotherapy drugs being tested for possible utilization ... non-chemotherapy drug (angiogenesis inhibitor) that was developed by VasGene Therapeutics, Inc. for the treatment of …
Glutaral
One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
Experimental
Matched Description: … One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive …
HX-1171
Hx 1171 is under investigation in clinical trial NCT01548391 (A Phase I Clinical Study Study of the Safety, Tolerability, and Pharmacokinetics of HX-1171 in Healthy Male Subjects).
Investigational
Matched Description: … , Tolerability, and Pharmacokinetics of HX-1171 in Healthy Male Subjects). ... Hx 1171 is under investigation in clinical trial NCT01548391 (A Phase I Clinical Study Study of the Safety …
PF-05089771
PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee).
Investigational
Matched Description: … PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee). ... PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of …
Yttrium Y-90 clivatuzumab tetraxetan
Yttrium Y-90 clivatuzumab tetraxetan is under investigation in clinical trial NCT00603863 (Safety and Efficacy Study of Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer).
Investigational
Matched Description: … Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer). ... clivatuzumab tetraxetan is under investigation in clinical trial NCT00603863 (Safety and Efficacy Study of …
Gusacitinib
Gusacitinib is under investigation in clinical trial NCT02550678 (A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma).
Investigational
Matched Description: … of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma). ... Gusacitinib is under investigation in clinical trial NCT02550678 (A Study of the Efficacy and Safety …
ABX-PTH
ABX-PTH is a fully human monoclonal antibody generated by Abgenix's technology platform. This drug targets and neutralizes the action of parathyroid hormone (PTH) for the treatment of a secondary hyperparathyroidism.
Investigational
Matched Description: … This drug targets and neutralizes the action of parathyroid hormone (PTH) for the treatment of a secondary …
HMR4011
HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid. IPL 576,092 has previously been investigated as a treatment for asthma.
Investigational
Matched Description: … from that of glucocorticoid. ... HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct …
PF-06260414
PF-06260414 is under investigation in clinical trial NCT02070939 (Study To Evaluate Safety And Tolerability Of Single And Multiple Ascending Doses Of PF- 06260414 In Healthy Western And Japanese Male Subjects).
Investigational
Matched Description: … Single And Multiple Ascending Doses Of PF- 06260414 In Healthy Western And Japanese Male Subjects). ... 06260414 is under investigation in clinical trial NCT02070939 (Study To Evaluate Safety And Tolerability Of …
ABP-700
ABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy).
Investigational
Matched Description: … is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of ... 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy). …
MRx-4DP0004
MRx-4DP0004 is a lyophilised formulation of the Bifidobacterium breve strain of commensal bacteria. It is a live biotherapeutic derived from the microbiota of a healthy human infant.
Investigational
Matched Description: … MRx-4DP0004 is a lyophilised formulation of the Bifidobacterium breve strain of commensal bacteria. ... It is a live biotherapeutic derived from the microbiota of a healthy human infant. …
APG-157
APG-157 consists of zinflavonoids being investigated for the treatment of cancers.
Investigational
Nutraceutical
Matched Description: … APG-157 consists of zinflavonoids being investigated for the treatment of cancers. …
SRP 299
SRP 299 is a preparation of killed Mycobacterium vaccae that has been tested in uses related to inhibiting periodontal disease, in treating asthma and in treating eczema, itching and inflammation. Mycobacterium vaccae is a non-pathogenic, saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity...
Investigational
Matched Description: … A specific subset of serotonergic neurons in the interfascicular part of the dorsal raphe nucleus (DRI ... SRP 299 is a preparation of killed Mycobacterium vaccae that has been tested in uses related to inhibiting ... saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity of …
BOS172722
BOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent. Normally, Mps1 supports the proper division of cancer cells, ensuring survival and replication. The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment,...
Experimental
Matched Description: … The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment ... [A187123] Normally, Mps1 supports the proper division of cancer cells, ensuring survival and replication ... [A187120] An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone …
Aetiocholanolone
The 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine. [PubChem]
Experimental
Matched Description: … The 5-beta-reduced isomer of androsterone. ... Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including …
Afelimomab
Afelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
Investigational
Matched Description: … Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis. …
PF-06751979
PF-06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults).
Investigational
Matched Description: … Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults). ... -06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of …
Hemoximer
Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.
Investigational
Matched Description: … Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering …
LB-001
LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA mutase (MUT) gene into the genome of patients with methylmalonic acidemia.
Investigational
Matched Description: … mutase (MUT) gene into the genome of patients with methylmalonic acidemia. ... LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA …
MBO7133
MB07133 is a HepDirect prodrug of an activated form of cytarabine (araC), an anti-cancer drug that is used to treat leukemia but is ineffective against primary liver cancer. AraC's anti-cancer activity is associated with its ability to be converted to its biologically active form, araCTP. However, araC is only slowly...
Investigational
Matched Description: … MB07133 is a HepDirect prodrug of an activated form of cytarabine (araC), an anti-cancer drug that is ... activation pathway of the drug. ... , araC is only slowly converted to araCTP in the liver or in primary liver tumors due to low levels of …
PSN9301
PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes. PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for...
Investigational
Matched Description: … treatment of type 2 diabetes. ... PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the ... PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical …
CNS-5161
CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.
Investigational
Matched Description: … CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials ... as a novel compound for the treatment of neuropathic pain. …
Albinterferon Alfa-2B
Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to improve its pharmacological properties by using the company's proprietary albumin fusion technology. Human...
Investigational
Matched Description: … of cancers. ... Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. ... Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range …
Pradefovir
Pradefovir is a prodrug of adefovir.
Investigational
Matched Description: … Pradefovir is a prodrug of [adefovir]. …
Besifovir dipivoxil
Besifovir dipivoxil is a small-molecule orally available inhibitor of the HBV polymerase. The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of RNA. Besifovir dipivoxil is believed to inhibit viral proliferation by interrupting the replicating machinery of the virus.
Investigational
Matched Description: … The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of ... Besifovir dipivoxil is a small-molecule orally available inhibitor of the HBV polymerase. ... Besifovir dipivoxil is believed to inhibit viral proliferation by interrupting the replicating machinery of …
Displaying drugs 10426 - 10450 of 12433 in total