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Displaying drugs 1026 - 1050 of 1311 in total
Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(multiple sclerosis-associated retrovirus viral envelope protein) (human-mus ... musculus monoclonal gnbac1 heavy chain), disulfide with human-mus musculus monoclonal gnbac1 kappa-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Iodopropynyl butyl carbamate
Experimental
Matched Name: … (4S)-4-(2-NAPHTHYLMETHYL)-D-GLUTAMIC ACID …
Upanovimab (SCTA01) was under investigation in clinical trials (NCT04683328, NCT04644185, NCT04709328 and NCT05156645) to evaluate its safety and efficacy in patients with severe COVID-19
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN) (HUMAN-MUS ... MUSCULUS MONOCLONAL SCTA01 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL SCTA01 .KAPPA …
Matched Description: … Upanovimab (SCTA01) was under investigation in clinical trials (NCT04683328, NCT04644185, NCT04709328 and ... NCT05156645) to evaluate its safety and efficacy in patients with severe COVID-19 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … 4-221-Colony-stimulating factor 1 (human clone p3ACSF-69 reduced) …
Beperminogene perplasmid is under investigation in clinical trial NCT02144610 (Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia).
Investigational
Matched Synonyms: … Dna (human hepatocyte growth factor plasmid pvax1 cdna) …
Matched Description: … Beperminogene perplasmid is under investigation in clinical trial NCT02144610 (Efficacy and Safety of …
Cerliponase alfa is a hydrolytic lysosomal N-terminal tripeptidyl peptidase-1 (TPP1). On April 27, 2017, cerliponase alfa was first approved by the FDA as the first treatment for neuronal ceroid lipofuscinosis type 2 (CLN2), also known as TPP1 deficiency. It was also approved by the EMA on May 30, 2017 and...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 ... RECOMBINANT HUMAN TRIPEPTIDYL PEPTIDASE-1 …
Matched Description: … [L51339] It was also approved by the EMA on May 30, 2017 [L51324] and by Health Canada on December 19 ... disease caused by a deficiency in the lysosomal enzyme TPP1, leading to progressive impairment in motor and ... [A264354, A264369] As a recombinant human TPP1, cerliponase alfa is used as an enzyme replacement therapy …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed...
Approved
Vet approved
Matched Synonyms: … O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
Matched Description: … Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 ... [T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956 ... Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid
Matched Categories: … Thyroid Products ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... combinations of levothyroxine and liothyronine …
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … for induction and/or maintenance of anaesthesia prior to and during surgeries. ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia ... Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … PROPOFOL-LIPURO 1% GLASS BOTTLE ... PROPOFOL-LIPURO 1% (20ML GLASS AMPOULE) …
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Experimental
Matched Name: … N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Experimental
Matched Name: … N-[(6-butoxynaphthalen-2-yl)sulfonyl]-L-glutamic acid …
Evening primrose oil comes from the extraction from Oenothera biennis seeds and it is commonly used as an alternative source for omega-6 essential fatty acids. In its composition it presents some fatty acids such as DB00132 and DB13854. Evening primrose oil has been filled for the FDA by Humanetics Corporation...
Investigational
Nutraceutical
Matched Description: … Evening primrose oil comes from the extraction from _Oenothera biennis_ seeds and it is commonly used ... In its composition it presents some fatty acids such as [DB00132] and [DB13854]. …
Matched Products: … GNC EVENING PRIMROSE OIL 1300MG WITH GLA & LA ... Nn EVENING PRIMROSE OIL 1000MG (with 10%GLA) ... Nn EVENING PRIMROSE OIL 500MG (with 10% GLA) …
Experimental
Matched Synonyms: … N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-γ-L-glutamyl}-L-glutamate
Matched Categories: … Enzymes and Coenzymes …
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Matched Synonyms: … Anti-CD 154 human-mouse monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Blood coagulation factor XIV (human) ... Recombinant human activated protein C (rH-APC) …
Matched Description: … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Investigational
Matched Synonyms: … HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10 ... INTERLEUKIN 22 (HUMAN (MATURE)) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (SYNTHETIC HUMAN .GAMMA.4-CHAIN …
Matched Description: … Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta, recombinant human ... Interferon beta-1a (recombinant human) …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Recombinant Human Interferon beta ... Intercellular Signaling Peptides and Proteins …
Iodinated I-131 serum albumin is a radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and the imaging of certain tissues.
Approved
Matched Synonyms: … Human albumin I-131 ... Human serum albumin I-131 ... Iodinated (131I) human serum albumin …
Matched Description: … radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and
Investigational
Matched Synonyms: … Peptide YY human ... Peptide YY (human) ... Peptide YY human (1-36) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human intercellular adhesion molecule icam-1) (human monoclonal bi-505 .gamma ... Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human
Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched Synonyms: … (2-hydroxypropyl)trimethylammonium carbamate
Matched Iupac: … 1-(trimethylazaniumyl)propan-2-yl carbamate
Matched Description: … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function ... to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system …
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Pegylated human interferon A-2B …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 1026 - 1050 of 1311 in total