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Displaying drugs 10476 - 10500 of 11799 in total
Chlorphenoxamine is marketed under the name Phenoxene. It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Withdrawn
Matched Iupac: … {2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}dimethylamine …
Matched Salts cas: … 562-09-4
Experimental
Matched Iupac: … 1-(prop-2-yn-1-yl)cyclohexyl carbamate …
Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE). The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling. This drug from BMS was not approved by the FDA due...
Investigational
Matched Iupac: … (4S,7S,10aS)-5-oxo-4-[(2S)-3-phenyl-2-sulfanylpropanamido]-octahydro-2H-pyrido[2,1-b][1,3]thiazepine- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched Salts cas: … 33032-12-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1( …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Niludipine is a calcium channel blocker.
Experimental
Matched Iupac: … 3,5-bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to increase palatability. Deramaxx received FDA approval in August 2002 for "the control of post operative pain and inflammation associated with...
Vet approved
Matched Iupac: … 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Landiolol is a rapid-acting beta-blocker used for rapid ventricular rate control.
Investigational
Matched Iupac: … [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-{4-[(2S)-2-hydroxy-3-({2-[(morpholine-4-carbonyl)amino] …
Matched Salts cas: … 144481-98-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines[A245368, A245373] and is also being investigated against eye-related diseases that are associated with local circulatory disturbances, an example being normal-tension glaucoma.
Experimental
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
gamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).
Investigational
Matched Iupac: … (2R)-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 2-Amino-6-Aminomethyl-8-Phenylsulfanylmethyl-3h-Quinazolin-4-One …
Matched Iupac: … 2-amino-6-(aminomethyl)-8-[(phenylsulfanyl)methyl]-3,4-dihydroquinazolin-4-one …
Experimental
Matched Name: … 2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine …
Matched Iupac: … N6-benzyl-9-cyclopentyl-N2-[(1r,4r)-4-aminocyclohexyl]-9H-purine-2,6-diamine …
Experimental
Matched Name: … 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile …
Matched Iupac: … 4-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3H-indole-2-carbonitrile …
Experimental
Matched Name: … (2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID …
Matched Iupac: … (2S,3S)-3-formyl-2-[(4-methylbenzenesulfonamido)methyl]pentanoic acid …
Experimental
Matched Iupac: … (3R,7R)-1-{[(2S)-1-({hydroxy[(2R)-2-hydroxy-3-(phosphonooxy)propoxy]phosphoryl}oxy)-3-{[(3R,7R)-3,7,11,15 …
Bufuralol is a new, non-selective -adrenoceptor blocking agent.
Experimental
Matched Iupac: … 2-(tert-butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethan-1-ol …
Experimental
Matched Iupac: … 1-{1-[2-(2-hydroxyethoxy)ethyl]-4-phenylpiperidin-4-yl}propan-1-one …
Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Iupac: … 1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2R)-1-{[(1S)-4-carbamimidamido ... -1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-(C-hydroxycarbonimidoyl)-2-(4-hydroxyphenyl)ethyl]-C-hydroxycarbonimidoyl ... [(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[( ... (4S)-4-({[(2S)-1-[(2S,3R)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[2-({[(2S)-1-[(2S)-2-{[(2S)-2-({[(2S)-1-[(2S) ... -2-{[(2S)-2-({[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-4- …
Experimental
Matched Name: … N-(4-{2-[(3-chlorobenzyl)amino]ethyl}phenyl)thiophene-2-carboximidamide …
Matched Iupac: … (Z)-N'-[4-(2-{[(3-chlorophenyl)methyl]amino}ethyl)phenyl]thiophene-2-carboximidamide …
Experimental
Matched Name: … N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE …
Matched Iupac: … N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]naphthalene-2-sulfonamide …
Experimental
Matched Name: … 2-butoxy-9-(2,6-difluorobenzyl)-N-(2-morpholin-4-ylethyl)-9H-purin-6-amine …
Matched Iupac: … 2-butoxy-9-[(2,6-difluorophenyl)methyl]-N-[2-(morpholin-4-yl)ethyl]-9H-purin-6-amine …
Experimental
Matched Name: … N-({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID …
Matched Iupac: … (2R)-2-{6-[(4-cyano-2-fluorophenyl)methoxy]naphthalene-2-sulfonamido}pentanedioic acid …
Experimental
Matched Name: … (2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID …
Matched Iupac: … (2S,3S)-3-formyl-2-[(4-nitrobenzenesulfonamido)methyl]pentanoic acid …
Displaying drugs 10476 - 10500 of 11799 in total