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Displaying drugs 10551 - 10575 of 12319 in total

Nimorazole

Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
Investigational
Matched Iupac: … 4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]morpholine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Hematoxylin

Investigational
Matched Iupac: … (1R,10S)-8-oxatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,12,14,16-hexaene-5,6,10,14,15-pentol …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Metenkefalin

Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido …
Matched Salts cas: … 82362-17-2 …

ADL5859

ADL5859 is a novel, oral compound that targets the Delta opioid receptor. Delta receptor agonists are thought to offer benefits over other approaches to the management of pain.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Omipalisib

Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis.
Investigational
Matched Iupac: … 2,4-difluoro-N-{2-methoxy-5-[4-(pyridazin-4-yl)quinolin-6-yl]pyridin-3-yl}benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Demplatin pegraglumer

Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational

9-(4-hydroxybutyl)-N2-phenylguanine

9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine is known to target thymidine kinase.
Experimental
Matched Iupac: … 9-(4-hydroxybutyl)-2-(phenylamino)-6,9-dihydro-1H-purin-6-one …

2-Dimethylamino-Ethyl-Diphosphate

Experimental
Matched Name: … 2-Dimethylamino-Ethyl-Diphosphate …
Matched Iupac: … ({[2-(dimethylamino)ethoxy](hydroxy)phosphoryl}oxy)phosphonic acid …

(3s)-2,3,4,5-Tetrahydropyridin-3-Amine

Experimental

Sulfachlorpyridazine

A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
Vet approved
Matched Iupac: … 4-amino-N-(6-chloropyridazin-3-yl)benzene-1-sulfonamide …
Matched Salts cas: … 1392129-96-2 …

Antithrombin gamma

Antithrombin gamma is under investigation in clinical trial NCT04182373 (KW-3357 Study in Patients With Early Onset Severe Preeclampsia).
Investigational

STRO-001

Investigational

Homocysteine

Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine.
Experimental
Matched Synonyms: … L-2-amino-4-mercaptobutyric acid …
Matched Iupac: … (2S)-2-amino-4-sulfanylbutanoic acid …

Cysteinamide

Experimental
Matched Synonyms: … 2-amino-3-mercapto-propionamide …
Matched Iupac: … (2R)-2-amino-3-sulfanylpropanamide …

Ricolinostat

Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
Investigational
Matched Iupac: … 7-{[2-(diphenylamino)pyrimidin-5-yl]formamido}-N-hydroxyheptanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Carboquone

Experimental
Matched Iupac: … 2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl carbamate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

GC-373

GC-373 is a peptide aldehyde which is metabolized from the bisulfide adduct, GC-376 free acid[A219031,A219036]. It is an inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease that cleaves and activates functional proteins involved in viral replication and transcription . GC-373 has been shown to inhibit the Mpro...
Experimental
Matched Iupac: … benzyl N-[(1S)-3-methyl-1-{[(2S)-1-oxo-3-(2-oxopyrrolidin-3-yl)propan-2-yl]carbamoyl}butyl]carbamate …
Matched Description: … with its prodrug, GC-376, GC-373 was recently investigated _in vitro_ in cell culture against SARS-Cov-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2,4-Dihydroxy-3,3-Dimethyl-Butyrate

Experimental

2,3-Di-O-Sulfo-Alpha-D-Glucopyranose

Experimental

2-chloro-5-nitro-N-phenylbenzamide

Experimental
Matched Name: … 2-chloro-5-nitro-N-phenylbenzamide …
Matched Iupac: … 2-chloro-5-nitro-N-phenylbenzamide …

4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID

Experimental
Matched Name: … 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID …
Matched Iupac: … 4-(2-aminophenyl)-4-oxobutanoic acid …

5-Chloryl-2,4,6-quinazolinetriamine

Experimental

N-(3-AMINOPROPYL)-2-NITROBENZENAMINE

Experimental
Matched Name: … N-(3-AMINOPROPYL)-2-NITROBENZENAMINE …
Matched Iupac: … N1-(2-nitrophenyl)propane-1,3-diamine …

Methyl salicylate 2-ethylbutyrate

Experimental
Matched Synonyms: … Salicylic acid, methyl ester, 2-ethylbutyrate …
Matched Name: … Methyl salicylate 2-ethylbutyrate …
Matched Iupac: … methyl 2-[(2-ethylbutanoyl)oxy]benzoate …

2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate)

Experimental
Matched Synonyms: … 5-hydroxymethyluridine-2'-deoxy-5'-monophosphate …
Matched Name: … 2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate) …
Matched Iupac: … {[(2R,3S,5R)-3-hydroxy-5-[5-(hydroxymethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2-yl]methoxy …
Displaying drugs 10551 - 10575 of 12319 in total