Displaying drugs 10701 - 10725 of 11311 in total
Vistusertib
Vistusertib is under investigation for the treatment of Advanced Gastric Adenocarcinoma.
Investigational
Matched Iupac: … 3-{2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl}-N-methylbenzamide …
Atevirdine
Atevirdine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … N-ethyl-2-[4-(5-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]pyridin-3-amine …
Iofolastat I-123
Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).
Investigational
Matched Iupac: … (2S)-2-({[(1S)-1-carboxy-5-({[4-(¹²³I)iodophenyl]methyl}amino)pentyl]carbamoyl}amino)pentanedioic acid …
Urapidil
Urapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.
Investigational
Matched Iupac: … 6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4- …
Dofequidar
Dofequidar is an antineoplastic agent.
Experimental
Investigational
Matched Iupac: … 1-{4-[2-hydroxy-3-(quinolin-5-yloxy)propyl]piperazin-1-yl}-2,2-diphenylethan-1-one …
Matched Salts cas: … 158681-49-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 158681-49-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
DCFBC F-18
DCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Investigational
Matched Iupac: … (2S)-2-({[(1R)-1-carboxy-2-({[4-(¹⁸F)fluorophenyl]methyl}sulfanyl)ethyl]carbamoyl}amino)pentanedioic …
MIP-1095 I-131
MIP-1095 I-131 is under investigation in clinical trial NCT03030885 (Use of an Experimental Radiopharmaceutical (131I-MIP-1095) in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC)).
Investigational
Matched Iupac: … (2S)-2-({[(1S)-1-carboxy-5-({[4-(¹³¹I)iodophenyl]carbamoyl}amino)pentyl]carbamoyl}amino)pentanedioic …
Flutriciclamide F-18
Flutriciclamide F-18 is under investigation in clinical trial NCT02350426 (A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques).
Investigational
Matched Iupac: … (4S)-N,N-diethyl-9-[2-(¹⁸F)fluoroethyl]-5-methoxy-2,3,4,9-tetrahydro-1H-carbazole-4-carboxamide …
TAK-653
TAK-653 is under investigation in clinical trial NCT03312894 (Efficacy and Safety of TAK-653 in Treatment-resistant Depression).
Investigational
Matched Iupac: … 9-[4-(cyclohexyloxy)phenyl]-7-methyl-3H,4H-2lambda6-pyrazino[2,1-c][1,2,4]thiadiazine-2,2-dione …
Emprumapimod
Emprumapimod is a potent, orally active and selective inhibitor of p38α mitogen-activated kinase inhibitor. It was investigated for dilated cardiomyopathy.
Investigational
Matched Iupac: … (2S)-2-{[5-(2,4-difluorophenoxy)-1-(2-methylpropyl)-1H-indazol-6-yl]formamido}-4-(dimethylamino)butanamide …
N-[O-Phosphono-Pyridoxyl]-Isoleucine
Experimental
Matched Iupac: … (2R,3S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-3-methylpentanoic …
9r,13r-Opda
Experimental
Matched Iupac: … 8-[(1R,5R)-4-oxo-5-(pent-2-en-1-yl)cyclopent-2-en-1-yl]octanoic acid …
Acadesine
Acadesine (AICA-riboside) is a purine nucleoside analog with anti-ischemic properties that is currently being studied (Phase 3) for the prevention of adverse cardiovascular outcomes in patients undergoing coronary artery bypass graft (CABG) surgery. It is being developed jointly by PeriCor and Schering-Plough. Acadesine has been granted Orphan Drug Designation for...
Investigational
Matched Iupac: … 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4-carboxamide …
Matched Description: … is a purine nucleoside analog with anti-ischemic properties that is currently being studied (Phase 3) …
Matched Description: … is a purine nucleoside analog with anti-ischemic properties that is currently being studied (Phase 3) …
WX-UK1
WX-UK1 is a 3-amidinophenylalanine-based non-cytotoxic small molecule that belongs to a new class of drugs. In animal models, WX-UK1 blocks tumor cell invasion, metastasis and primary tumor growth by inhibiting serine proteases and the urokinase Plasminogen Activator (uPA) system, which have been shown to play a key role in metastasis...
Investigational
Matched Iupac: … ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-[2,4,6-tris(propan-2-yl)benzenesulfonamido]propanoyl]piperazine …
Matched Description: … WX-UK1 is a 3-amidinophenylalanine-based non-cytotoxic small molecule that belongs to a new class of …
Matched Description: … WX-UK1 is a 3-amidinophenylalanine-based non-cytotoxic small molecule that belongs to a new class of …
PPL-100
Investigational
Matched Iupac: … methyl N-[(1S)-1-{[(5S)-6-hydroxy-5-[N-(2-methylpropyl)4-aminobenzenesulfonamido]hexyl]carbamoyl}-2,2 …
Tariquidar
Investigational
Matched Iupac: … N-[2-({4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]phenyl}carbamoyl)-4,5-dimethoxyphenyl ... ]quinoline-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vipadenant
Investigational
Matched Iupac: … 3-[(4-amino-3-methylphenyl)methyl]-7-(furan-2-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine …
Rabusertib
Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer.
Investigational
Matched Iupac: … 3-(5-bromo-4-methyl-2-{[(2S)-morpholin-2-yl]methoxy}phenyl)-1-(5-methylpyrazin-2-yl)urea …
Vestipitant
Vestipitant has been investigated for the treatment of Tinnitus.
Investigational
Matched Iupac: … (2S)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperazine- …
Letaxaban
Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.
Investigational
Matched Iupac: … 1-{1-[(2S)-3-[(6-chloronaphthalen-2-yl)sulfonyl]-2-hydroxypropanoyl]piperidin-4-yl}-1,3-diazinan-2-one …
Hydroquinidine
Hydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome).
Investigational
Matched Iupac: … (S)-[(1S,2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Trelagliptin
Trelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus").
Investigational
Matched Iupac: … 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)-4-fluorobenzonitrile …
Matched Description: … NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 …
Matched Description: … NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 …
Hesperidin methylchalcone
Experimental
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)-1-(2-hydroxy-6-methoxy-4-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[ ... (2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}phenyl)prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ozekibart
Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Investigational
Matched Synonyms: … 5) (human-Lama glama clone IF5 single-domain VHH fragment) fusion protein with peptide linker (GGS)2 …
Motesanib
Investigational
Matched Iupac: … N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide …
Matched Salts cas: … 857876-30-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 857876-30-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 10701 - 10725 of 11311 in total