Displaying drugs 10751 - 10775 of 13180 in total
Tienilic acid
Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Withdrawn
Matched Synonyms: … (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid ... 4-(2-Theonyl)-2,3-dichlorphenoxyessigsäure ... 4-(2-Thienylketo)-2,3-dichlorophenoxyacetic acid …
Matched Iupac: … 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Etifoxine
Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an...
Investigational
Withdrawn
Matched Iupac: … 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
LGD2941
LGD2941 is a non-steroidal, selective androgen receptor modulator (SARM) developed jointly by Ligand and TAP.
Investigational
Matched Iupac: … 6-[(2R,5R)-2-methyl-5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-4-(trifluoromethyl)-1,2-dihydroquinolin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ocinaplon
Investigational
Matched Iupac: … 4-[3-(pyridine-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cutamesine
Investigational
Matched Iupac: … 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Galunisertib
Galunisertib has been used in trials studying the basic science and treatment of Glioma, Neoplasms, Solid Tumor, GLIOBLASTOMA, and Prostate Cancer, among others.
Investigational
Matched Iupac: … 4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Figopitant
Figopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers).
Investigational
Matched Iupac: … (2S)-N-{2-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-[4-(cyclopropylmethyl)piperazin-1-yl]-N-methyl-2-phenylacetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Domiodol
Experimental
Matched Iupac: … [2-(iodomethyl)-1,3-dioxolan-4-yl]methanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Milciclib Maleate
Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy).
Investigational
Matched Iupac: … N,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-1H,4H,5H-pyrazolo[4,3-h]quinazoline-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Detomidine
Detomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride. This drug is prescribed by veterinarians and is marketed as Dormosedan. Currently, it is only approved by the FDA for use in horses but has been studied for...
Vet approved
Matched Synonyms: … 4-(2,3-dimethylbenzyl)imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Chlorophetanol
Chlorophetanol is an agent known to have antifungal activities.
Experimental
Matched Synonyms: … 2-(4-Chlorophenoxy)ethanol ... 2-(4-chlorphenoxy)-ethanol …
Matched Iupac: … 2-(4-chlorophenoxy)ethan-1-ol …
Matched Categories: … 2-(4-chlorphenoxy)-ethanol …
Matched Iupac: … 2-(4-chlorophenoxy)ethan-1-ol …
Matched Categories: … 2-(4-chlorphenoxy)-ethanol …
GO-203-2C
GO-203-2C is under investigation in clinical trial NCT02204085 (A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Investigational
Matched Iupac: … )ethyl]-1,2-dithia-5,8-diazacycloundeca-5,8-dien-4-yl](hydroxy)methylidene}amino)-1-hydroxypentylidene ... (2R)-2-{[(2R)-6-amino-2-{[(2R)-5-carbamimidamido-2-{[(2R)-5-carbamimidamido-2-({[(4S,7R,10S)-10-{[(2R ... ]amino}-1-hydroxypentylidene]amino}-1-hydroxypentylidene]amino}-1-hydroxypentylidene]amino}-1-hydroxypentylidene ... hydroxy-2-[(1-hydroxyethylidene)amino]pentylidene]amino}-1-hydroxypentylidene]amino}-1-hydroxypentylidene ... ]amino}-1-hydroxypentylidene]amino}-1-hydroxyhexylidene]amino}-3-(C-hydroxycarbonimidoyl)propanoic acid …
RG-2833
Investigational
Matched Synonyms: … N-(6-(2-aminophenylamino)-6-oxohexyl)-4-methylbenzamide …
Matched Iupac: … N-(2-aminophenyl)-6-[(4-methylphenyl)formamido]hexanamide …
Matched Iupac: … N-(2-aminophenyl)-6-[(4-methylphenyl)formamido]hexanamide …
Vatalanib
Vatalanib (PTK787/ZK-222584) is a new oral antiangiogenic molecule that inhibits all known vascular endothelial growth factor receptors. Vatalanib is under investigation for the treatment of solid tumors.
Investigational
Matched Iupac: … N-(4-chlorophenyl)-4-[(pyridin-4-yl)methyl]phthalazin-1-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cloperastine
Cloperastine is a cough suppressant that acts on the central nervous system.
Experimental
Matched Iupac: … 1-{2-[(4-chlorophenyl)(phenyl)methoxy]ethyl}piperidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dasolampanel etibutil
Dasolampanel etibutil has been used in trials studying the treatment of Diabetic Neuropathy, Painful.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AZD-9164
AZD9164 has been used in trials studying the basic science and treatment of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … (3R)-1-[2-(4-fluorophenyl)ethyl]-3-{[(2S)-2-phenyl-2-(piperidin-1-yl)propanoyl]oxy}-1-azabicyclo[2.2.2 ... ]octan-1-ium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cinepazide
Cinepazide has been used in trials studying the treatment of Ischemic Stroke.
Investigational
Matched Iupac: … (2E)-1-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one …
Matched Salts cas: … 26328-04-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 26328-04-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Apitolisib
Apitolisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Prostate Cancer, Renal Cell Carcinoma, and Endometrial Carcinoma, among others.
Investigational
Matched Iupac: … (2S)-1-(4-{[2-(2-aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}piperazin ... -1-yl)-2-hydroxypropan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
LY-2584702
LY2584702 has been used in trials studying the treatment of Cancer, Advanced Cancer, Renal Cell Carcinoma, Metastases, Neoplasm, and Neuroendocrine Tumors, among others.
Investigational
Matched Iupac: … 4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-{1H-pyrazolo[3,4-d]pyrimidin-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pyrrobutamine
Experimental
Matched Iupac: … 1-[4-(4-chlorophenyl)-3-phenylbut-2-en-1-yl]pyrrolidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
JNJ-26489112
JNJ-26489112 is under investigation in clinical trial NCT00579384 (A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ampreloxetine
Ampreloxetine is under investigation in clinical trial NCT03750552 (Clinical Effect of TD-9855 for Treating snOH in Subjects With Primary Autonomic Failure).
Investigational
Matched Iupac: … 4-{2-[(2,4,6-trifluorophenoxy)methyl]phenyl}piperidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Navoximod
Navoximod is under investigation in clinical trial NCT02048709 (Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors).
Investigational
Matched Iupac: … (1R,4r)-4-[(1R)-2-[(5S)-6-fluoro-5H-imidazo[4,3-a]isoindol-5-yl]-1-hydroxyethyl]cyclohexan-1-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ensifentrine
Ensifentrine is under investigation in clinical trial NCT04535986 (A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD).
Investigational
Matched Iupac: … {2-[(2E)-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-2H,3H,4H,6H,7H-pyrimido[4,3-a]isoquinolin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10751 - 10775 of 13180 in total