Displaying drugs 10801 - 10825 of 11800 in total
Pexelizumab
Pexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. It is being investigated by Alexion Pharmaceuticals.
Investigational
Matched Description: … Pexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. …
PPI-2458
PPI-2458 represents a potentially new and important addition to the growing list of therapeutics aimed at specific molecular oncology targets. PPI-2458 is a novel, proprietary molecule belonging to the fumagillin class of compounds that specifically targets the MetAP-2 enzyme. This class of compounds has been shown to prevent both abnormal...
Investigational
Matched Description: … PPI-2458 represents a potentially new and important addition to the growing list of therapeutics aimed ... PPI-2458 is a novel, proprietary molecule belonging to the fumagillin class of compounds that specifically …
Tertatolol
Tertatolol is a beta blocker.
Experimental
Matched Description: … Tertatolol is a beta blocker. …
IDD-3
IDD-3 is a therapeutic specific immunostimulant developed by IDM Pharma in partnership with sanofi-aventis. It consists of mature dendritic cells loaded with lysates from melanoma tumor cell lines. It includes Dendritophages that are dendritic cells, a type of specialized immune cells derived from the patient's own white blood cells.
Investigational
Matched Description: … IDD-3 is a therapeutic specific immunostimulant developed by IDM Pharma in partnership with sanofi-aventis ... It includes Dendritophages that are dendritic cells, a type of specialized immune cells derived from …
Thienylfentanyl
Thienylfentanyl is a fentanyl analog analgesic that was sold on the black market in the 1980s until the Federal Analog Act scheduled drugs based on structural similarity rather than scheduling drugs individually. Thienylfentanyl has a similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide.
Illicit
Matched Description: … Thienylfentanyl is a fentanyl analog analgesic that was sold on the black market in the 1980s until the ... Thienylfentanyl has a similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted …
OTL-201
OTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of mucopolysaccharidosis type IIIA (MPS-IIIA). It consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem cells.
Investigational
Matched Description: … It consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase …
DG041
DG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and its complications.
DG041, an anti-platelet compound, has shown to be a selective and potent antagonist of the EP3 receptor for prostaglandins E2. EP3 is a target that associates with increased risk of various vascular...
Investigational
Matched Description: … EP3 is a target that associates with increased risk of various vascular diseases. ... DG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention ... DG041, an anti-platelet compound, has shown to be a selective and potent antagonist of the EP3 receptor …
Sirna-027
Sirna-027 is a chemically modified short interfering RNA(siRNA) targeting Vascular Endothelial Growth Factor Receptor-1(VEGFR-1). VEGFR-1 is a key component of the clinically validated vascular endothelial growth factor (VEGF) pathway. Sirna-027 is developed by Sirna Therapeutics and is under the phase I of clinical trails. It is used to treat Macular...
Investigational
Matched Description: … Sirna-027 is a chemically modified short interfering RNA(siRNA) targeting Vascular Endothelial Growth ... VEGFR-1 is a key component of the clinically validated vascular endothelial growth factor (VEGF) pathway …
GlycoPEG-GCSF
GlycoPEG-GCSF is a long-acting GlycoPEGylated granulocyte colony stimulating factor for the treatment of chemotherapy-induced neutropenia.
Investigational
Matched Description: … GlycoPEG-GCSF is a long-acting GlycoPEGylated granulocyte colony stimulating factor for the treatment …
D-threo-neopterin
A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.
Experimental
Matched Description: … A pteridine derivative present in body fluids; elevated levels result from immune system activation, ... (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin. …
SIG-001
SIG-001 is a cultured human retinal pigment epithelial cell line (ARPE-19) genetically modified with a non-viral vector to express B domain deleted human factor VIII protein, encapsulated within two-layer modified alginate spheres.
Investigational
Matched Description: … SIG-001 is a cultured human retinal pigment epithelial cell line (ARPE-19) genetically modified with ... a non-viral vector to express B domain deleted human factor VIII protein, encapsulated within two-layer …
BL-1020
BL-1020 is a first in class novel compound for the treatment of schizophrenia. It is being developed by BioLineRx (BioLine).
Investigational
Matched Description: … BL-1020 is a first in class novel compound for the treatment of schizophrenia. …
HCV-086
HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the hepatitis C virus.
Investigational
Matched Description: … HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the …
Senicapoc
Senicapoc (ICA-17043) is a novel Gardos channel blocker. It is being investigated for the treatment of sickle cell disease.
Investigational
Matched Description: … Senicapoc (ICA-17043) is a novel Gardos channel blocker. …
Fluorine F-18
Fluorine-18 is under investigation in clinical trial NCT00870974 (A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions).
Investigational
Matched Description: … Fluorine-18 is under investigation in clinical trial NCT00870974 (A PET Brain Imaging Study of mGluR5 …
Tribulus terrestris
Tribulus terrestris is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Tribulus terrestris is a plant/plant extract used in some OTC (over-the-counter) products. …
Chondrus crispus
Chondrus crispus is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Chondrus crispus is a plant/plant extract used in some OTC (over-the-counter) products. …
Chicory leaf
Chicory leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Chicory leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
Deutivacaftor
Deutivacaftor is under investigation in clinical trial NCT03227471 (A Study of VX-445 in Healthy Subjects and Subjects With Cystic Fibrosis).
Investigational
Matched Description: … Deutivacaftor is under investigation in clinical trial NCT03227471 (A Study of VX-445 in Healthy Subjects …
MK-0736
MK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial Plaque (0736-006)(TERMINATED)).
Investigational
Matched Description: … MK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial …
Sepiapterin
Sepiapterin is under investigation in clinical trial NCT03519711 (A Study of CNSA-001 in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalaninemia).
Investigational
Matched Description: … Sepiapterin is under investigation in clinical trial NCT03519711 (A Study of CNSA-001 in Primary Tetrahydrobiopterin …
Mibavademab
Mibavademab is under investigation in clinical trial NCT04159415 (Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy).
Investigational
Matched Description: … Mibavademab is under investigation in clinical trial NCT04159415 (Study of REGN4461, a Leptin Receptor …
BS-001
BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human use (rHSV2hGM-CSF).
Investigational
Matched Description: … BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell …
Petosemtamab
Petosemtamab is under investigation in clinical trial NCT03526835 (A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors).
Investigational
Matched Description: … Petosemtamab is under investigation in clinical trial NCT03526835 (A Study of Bispecific Antibody MCLA …
Displaying drugs 10801 - 10825 of 11800 in total