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Displaying drugs 11251 - 11275 of 13283 in total

Recombinant human placental growth factor (PLGF-131)

Investigational

Coltuximab ravtansine

Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic leukemia (ALL).
Investigational

Bencyclane

A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
Experimental
Matched Synonyms: … 3-((1-Benzylcycloheptyl)oxy)-N,N-dimethylpropylamin …
Matched Iupac: … {3-[(1-benzylcycloheptyl)oxy]propyl}dimethylamine …
Matched Salts cas: … 14286-84-1 …

Col-Treg

Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.
Investigational
Matched Synonyms: … Purified autologous type 1 regulatory T lymphocytes specific for human type II collagen …

3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE

Experimental
Matched Name: … 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE …
Matched Iupac: … 3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine …

Recombinant human palmitoyl protein thioesterase-1

Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …

Pranlukast

Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Investigational
Matched Iupac: … N-[4-oxo-2-(2H-1,2,3,4-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenylbutoxy)benzamide …
Matched Description: … Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE

Experimental
Matched Name: … 5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE …
Matched Iupac: … 5-[4-(dimethylamino)phenyl]-6-{2-[6-(morpholin-4-yl)pyridin-3-yl]ethynyl}pyrimidin-4-amine …

BGA002

Investigational

Zelpultide alfa

Zelpultide alfa is a recombinant human surfactant protein D.
Investigational

Rapastinel

Rapastinel has been used in trials studying the treatment of Depressive Disorder, Major and Obsessive-Compulsive Disorder (OCD).
Investigational
Matched Iupac: … (2S,3R)-2-{[(2S)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl] …

Cannabinol

Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Experimental
Investigational
Matched Synonyms: … 6,6,9-Trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol …
Matched Iupac: … 6,6,9-trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol …

Temelimab

Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational

Dovitinib

Dovitinib is an orally active small molecule that exhibits potent inhibitory activity against multiple RTKs involved in tumor growth and angiogenesis. Preclinical data show that dovitinib works to inhibit multiple kinases associated with different cancers, including acute myeloid leukemia (AML) and multiple myeloma. Chiron currently has three ongoing Phase I...
Investigational
Matched Iupac: … 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one …
Matched Salts cas: … 915769-50-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Orotic acid

Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Acetophenone

Experimental
Matched Synonyms: … 1-phenylethanone …
Matched Iupac: … 1-phenylethan-1-one …

BI-836858

Investigational

Marstacimab

Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and hemophilia B.
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human tissue factor pathway inhibitor) (human monoclonal pf-06741086 .gamma.1- …

L-N(omega)-nitroarginine-(4R)-amino-L-proline amide

Experimental
Matched Iupac: … (2S,4R)-4-[(2S)-2-amino-5-[(E)-[amino(nitroamino)methylidene]amino]pentanamido]pyrrolidine-2-carboxamide …

Glutathionylspermidine

Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-{[({3-[(4-aminobutyl)amino]propyl}-C-hydroxycarbonimidoyl)methyl]-C-hydroxycarbonimidoyl ... }-2-sulfanylethyl]-C-hydroxycarbonimidoyl}butanoic acid …

Nicotinamide 8-bromo-adenine dinucleotide phosphate

Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-5-{[({[(2R,3R,4R,5R)-5-(6-amino-8-bromo-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan ... -pyridin-1-ylium ... -2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5 …

Cibisatamab

Investigational

Etigilimab

Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Investigational
Matched Synonyms: … tigit(t-cell immunoreceptor with ig and itim domains)) (humanized mouse monoclonal omp-313m32 .gamma.1- …

AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH

Experimental
Matched Iupac: … [(1R)-4-amino-1-{[(2S)-1-[(2R)-2-acetamido-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}butyl]boronic …

GDC-0917

CUDC-427 has been used in trials studying the treatment of LYMPHOMA and Solid Cancers.
Investigational
Matched Iupac: … 1,3-thiazol-5-yl]pyrrolidine-2-carboxamide ... (2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]-N-[2-(1,3-oxazol-2-yl)-4-phenyl- …
Displaying drugs 11251 - 11275 of 13283 in total