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Displaying drugs 11276 - 11300 of 11832 in total
Motolimod
Motolimod has been used in trials studying the treatment of Lymphoma, Tongue Cancer, Ovarian Cancer, Adult Solid Neoplasm, and Fallopian Tube Cancer, among others.
Investigational
Matched Description: … Motolimod has been used in trials studying the treatment of Lymphoma, Tongue Cancer, Ovarian Cancer, …
Gavestinel
Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM). Gavestinel displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites and is orally bioavailable and active in vivo.
Investigational
Matched Description: … 1000-fold selectivity over NMDA, AMPA and kainate binding sites and is orally bioavailable and active in …
SynOV1.1
SynOV1.1 is an investigational cancer immunotherapy developed by SyngenTech. It is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating factor cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF). SynOV1.1 is under investigation in clinical trial NCT04612504 (Synov1.1 Intratumoral Injection Study).
Investigational
Matched Description: … SynOV1.1 is under investigation in clinical trial NCT04612504 (Synov1.1 Intratumoral Injection Study) …
AEM-28-14
AEM-28-14 is an analog of AEM-28, an apolipoprotein E mimetic peptide, with a 400 percent greater cholesterol-lowering efficacy and a several-fold increase in drug tolerability. It is being investigated for lipid disorders such as homozygous familial hypercholesterolemia.
Investigational
Matched Description: … mimetic peptide, with a 400 percent greater cholesterol-lowering efficacy and a several-fold increase in …
Abivertinib
Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. In binding to and inhibiting EGFR and BTK receptors,...
Investigational
Matched Description: … The study is expected to be completed in March 2021.[L17398] ... [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and ... [L17388]
Abivertinib's potential to depress cytokine production has led to its investigation in the …
Afimetoran
Afimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8.[L32018, L32023] It is also is under investigation in clinical trial NCT04269356 (Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male Participants).
Investigational
Matched Description: … [L32018, L32023] It is also is under investigation in clinical trial NCT04269356 (Study to Assess the ... Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male …
Amcipatricin
Amcipatricin has been used in trials studying the treatment of Cryptococcosis or Aspergillosis Infections. Amcipatricin (as amcipatricin diascorbate; SPK-843) is a water-soluble partricin derivative patented by SPA Societa Prodotti Antibiotici S.p.A. and developed by Aparts and Kaken for the potential treatment of systemic fungal infections. In preclinical models, SPK-843 shows...
Investigational
Matched Description: … In preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of ... Amcipatricin has been used in trials studying the treatment of Cryptococcosis or Aspergillosis Infections …
Fedovapagon
Fedovapagon has been used in trials studying the treatment of Nocturia.
Investigational
Matched Description: … Fedovapagon has been used in trials studying the treatment of Nocturia. …
Zicronapine
Zicronapine has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Description: … Zicronapine has been used in trials studying the treatment of Schizophrenia. …
Anrukinzumab
Anrukinzumab has been used in trials studying the diagnostic of Asthma.
Investigational
Matched Description: … Anrukinzumab has been used in trials studying the diagnostic of Asthma. …
Tandospirone
Tandospirone has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Description: … Tandospirone has been used in trials studying the treatment of Schizophrenia. …
2,2-bis(4-hydroxy-3-tert-butylphenyl)propane
TBD has been used in trials studying the treatment of Adenocarcinoma.
Investigational
Matched Description: … TBD has been used in trials studying the treatment of Adenocarcinoma. …
Trimegestone
Trimegestone has been used in trials studying the treatment of Postmenopause.
Investigational
Matched Description: … Trimegestone has been used in trials studying the treatment of Postmenopause. …
Tropatepine
Tropatepine has been used in France for its antiparkinsons activities .
Experimental
Matched Description: … Tropatepine has been used in France for its antiparkinsons activities [A175024]. …
2'-Deoxycytidine-5'-Monophosphate
Deoxycytidine (dihydrogen phosphate). A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions. [PubChem]
Experimental
Matched Description: … A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the …
Psilocybin
Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Investigational
Matched Description: … In November, 2019, it was granted Breakthrough Therapy status by the FDA. …
Mirodenafil
Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
Investigational
Matched Description: … Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic …
Gedatolisib
Gedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer, Breast Cancer, Advanced Cancer, and Endometrial Cancer, among others.
Investigational
Matched Description: … Gedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer …
Fluorescein lisicol
Fluorescein lisicol has been used in trials studying the diagnostic of Pharmacokinetics, Hepatic Cirrhosis, Hepatitis, Viral, Human, Nonalcoholic Steatohepatitis, and Non-Alcoholic Fatty Liver Disease.
Investigational
Matched Description: … Fluorescein lisicol has been used in trials studying the diagnostic of Pharmacokinetics, Hepatic Cirrhosis …
Squaric acid dibutyl ester
Squaric acid dibutyl ester is under investigation in clinical trial NCT01971385 (Safety and Efficacy of Squaric Acid Dibutyl Ester for the Treatment of Herpes Labialis).
Investigational
Matched Description: … Squaric acid dibutyl ester is under investigation in clinical trial NCT01971385 (Safety and Efficacy …
Resminostat
Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others.
Investigational
Matched Description: … Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's …
Triciribine
Triciribine has been used in trials studying the treatment of Leukemia, Ovarian Cancer, HER2/Neu Negative, Breast Adenocarcinoma, and Stage IV Breast Cancer, among others.
Investigational
Matched Description: … Triciribine has been used in trials studying the treatment of Leukemia, Ovarian Cancer, HER2/Neu Negative …
ALM201
ALM201 is an anti-angiogenic synthetic peptide identified from the endogenous human protein, FKBPL. It is being investigated in the treatment of various cancers.
Investigational
Matched Description: … It is being investigated in the treatment of various cancers.[A254556] …
Distigmine
Distigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to DB00545 and DB01400. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase inhibitor that binds directly and competitively to the agonist binding sites of muscurinic receptors. Distigmine is available in several countries...
Experimental
Matched Description: … in the urinary tract where the active ingredient is distigmine bromide. ... Distigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction ... It improves detrusor function thereby restoring normal voiding patterns in patients suffering from detrusor …
Displaying drugs 11276 - 11300 of 11832 in total