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Displaying drugs 11351 - 11375 of 12677 in total
PF-05089771
PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee).
Investigational
Matched Description: … PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee). ... PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of …
Potassium bitartrate
Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as...
Experimental
Matched Description: … used as an additive, stabilizer, pH control agent, antimicrobial agent, processing aid, or thickener in ... Potassium bitartrate was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that ... medical use as a laxative administered as a rectal suppository and is an approved third-class OTC drug in …
N-(2-Aminoethyl)-1-aziridineethanamine
First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Experimental
Matched Description: … First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental ... angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease …
AGG-523
AGG-523 is under investigation in clinical trial NCT00380900 (Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy subjects and in subjects with osteoarthritis).
Investigational
Matched Description: … , Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy subjects and in subjects ... AGG-523 is under investigation in clinical trial NCT00380900 (Study Evaluating the Safety, Tolerability …
Enibarcimab
Enibarcimab is under investigation in clinical trial NCT03989531 (Adrecizumab in Cardiogenic Shock).
Investigational
Matched Description: … Enibarcimab is under investigation in clinical trial NCT03989531 (Adrecizumab in Cardiogenic Shock). …
Melperone
Melperone is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol. Melperone has been used for a span of greater than 30 years in the European Union . It has been well established in the treatment of confusion, anxiety, restlessness (particularly in...
Investigational
Matched Description: … It has been well established in the treatment of confusion, anxiety, restlessness (particularly in the ... Melperone has been used for a span of greater than 30 years in the European Union [L1316]. …
Adecatumumab
Adecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity to epithelial cell adhesion molecule (EpCAM). EpCAM (CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian, pancreatic and lung cancer.
Investigational
Grn163l
GRN163L is a novel anti-cancer drug. It has been characterized preclinically and shown to inhibit telomerase in human tumor cells of many cancer types (including lung, breast, prostate, liver, and early stage of human breast cancer), in both cell culture systems and animal models. Study of this drug shows the...
Investigational
Matched Description: … It has been characterized preclinically and shown to inhibit telomerase in human tumor cells of many ... cancer types (including lung, breast, prostate, liver, and early stage of human breast cancer), in both ... Study of this drug shows the its potential utility in the treatment of patients with hematologic and …
RG2417
RG2417 is a proprietary formulation of uridine, a biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in all cells, and numerous other factors essential for cell metabolism. Uridine is synthesized by the mitochondria, the power plant of the human cell responsible for energy...
Investigational
Matched Description: … biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in ... indicate that certain genes that encode for mitochondrial proteins are significantly down regulated in ... The rationale for uridine therapy in neuropsychiatric disorders is supported by preclinical and clinical …
ATG002
ATG002 is a completely new approach to treating chronic wounds such as diabetic foot ulcers, which is based upon stimulation of angiogenesis in the wound bed to help drive the wound-healing process. Unlike protein-derived growth factors, ATG002 is a small molecule that, applied topically, effectively penetrates through the wound and...
Investigational
Matched Description: … treating chronic wounds such as diabetic foot ulcers, which is based upon stimulation of angiogenesis in …
GPI-1485
GPI 1485 is a product candidate that belongs to a class of small molecule compounds called neuroimmunophilin ligands.
In preclinical experiments, neuroimmunophilin ligands have been shown to repair and regenerate damaged nerves without affecting normal, healthy nerves.
GPI 1485 is being studied in phase 2 clinical trials for the treatment...
Investigational
Matched Description: … erectile dysfunction and in pre-clinical development for HIV related dementia and neuropathy. ... In preclinical experiments, neuroimmunophilin ligands have been shown to repair and regenerate damaged ... GPI 1485 is being studied in phase 2 clinical trials for the treatment of Parkinson's disease and post-prostatectomy …
DP-b99
DP-b99 is a newly developed lipophilic, cell permeable derivative of BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), that is under development as a neuroprotectant for the potential treatment of stroke, head trauma and neurological damage associated with coronary artery bypass graft.
Investigational
GlycoPEG-GCSF
GlycoPEG-GCSF is a long-acting GlycoPEGylated granulocyte colony stimulating factor for the treatment of chemotherapy-induced neutropenia.
Investigational
Elsiglutide
Investigational
Annamycin
Investigational
AN-9
Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low toxicity and significant anticancer activity in vitro and in vivo. It shows greater potency than BA at inducing malignant cell differentiation and tumor growth inhibition and has demonstrated more favorable toxicological, pharmacological, and pharmaceutical properties than BA...
Investigational
Matched Description: … vitro and in vivo. ... acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low toxicity and significant anticancer activity in ... has demonstrated more favorable toxicological, pharmacological, and pharmaceutical properties than BA in …
SRP 299
SRP 299 is a preparation of killed Mycobacterium vaccae that has been tested in uses related to inhibiting periodontal disease, in treating asthma and in treating eczema, itching and inflammation. Mycobacterium vaccae is a non-pathogenic, saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity...
Investigational
Matched Description: … periodontal disease, in treating asthma and in treating eczema, itching and inflammation. ... SRP 299 is a preparation of killed Mycobacterium vaccae that has been tested in uses related to inhibiting ... A specific subset of serotonergic neurons in the interfascicular part of the dorsal raphe nucleus (DRI …
VX-765
VX-765 is the orally available prodrug of a potent and selective competitive inhibitor of ICE/caspase-1 (VRT-043198). VX-765 is currently under clinical development for the treatment of inflammatory and autoimmune conditions, as it blocks the hypersensitive response to an inflammatory stimulus.
Investigational
Asvasiran
Asvasiran is an siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication. It has the potential to treat or prevent RSV infection.
Investigational
Sivifene
Investigational
IMO-2055
Investigational
Tanomastat
Investigational
Repifermin
Investigational
Drinabant
AVE-1625 is an oral selective and potent antagonist of cannabinoid 1 (CB1) receptors having the same mechanism of action as rimonabant. It is currently developed in obesity and its associated comorbidities. AVE-1625 is also being developed for the treatment of Alzheimer disease.
Investigational
Matched Description: … It is currently developed in obesity and its associated comorbidities. …
Displaying drugs 11351 - 11375 of 12677 in total