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Displaying drugs 11551 - 11575 of 13528 in total
Epofolate
Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells. In Phase I/IIa pharmacokinetic and safety studies epofolate was generally tolerable and toxicities known to...
Investigational
Matched Iupac: … dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-5,9-dioxo-4-oxa- ... -4-carbamimidamido-1-{[(1S)-2-carboxy-1-{[(1R)-1-carboxy-2-({2-[({2-[(1S,3S,7S,10R,11S,12S,16R)-7,11- ... (2S)-2-[(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]-4-{[(1S)-1-{[(1S) ... heptadecan-17-yl]ethoxy}carbonyl)oxy]ethyl}disulfanyl)ethyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Methyclothiazide
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Withdrawn
Matched Iupac: … 6-chloro-3-(chloromethyl)-2-methyl-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Propyl Gallate
Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).
Investigational
OMS906
OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
Matched Synonyms: … (MASP-3) ... immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine protease-3 …
Matched Description: … (MASP-3) currently being developed by Omeros. ... OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 …
Matched Description: … (MASP-3) currently being developed by Omeros. ... OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 …
5-monophosphate-9-beta-D-ribofuranosyl xanthine
Experimental
Matched Name: … 5-monophosphate-9-beta-D-ribofuranosyl xanthine …
Matched Iupac: … 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-2,6-dioxo-2,3,6,7-tetrahydro-1H-9lambda5 …
Matched Iupac: … 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-2,6-dioxo-2,3,6,7-tetrahydro-1H-9lambda5 …
Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate
Experimental
Matched Name: … Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate …
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID
Experimental
Matched Name: … 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID …
Phencyclidine
A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As...
Illicit
Matched Synonyms: … 1-(1-Phenylcyclohexyl)piperidine …
Matched Iupac: … 1-(1-phenylcyclohexyl)piperidine …
Matched Salts cas: … 956-90-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-(1-phenylcyclohexyl)piperidine …
Matched Salts cas: … 956-90-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rilotumumab
Rilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer, and Prostate Cancer, among others.
Investigational
Tivirapine
Experimental
Matched Iupac: … (11S)-7-chloro-11-methyl-10-(3-methylbut-2-en-1-yl)-1,3,10-triazatricyclo[6.4.1.0^{4,13}]trideca-4(13 ... ),5,7-triene-2-thione …
Urtoxazumab
Investigational
B7-H3-specific chimeric antigen receptor T cells
Investigational
Orvepitant
Orvepitant has been used in trials studying the treatment of Depressive Disorder, Depressive Disorder, Major, Post-Traumatic Stress Disorder, and Posttraumatic Stress Disorder (PTSD).
Investigational
Matched Iupac: … ]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide ... (2R,4S)-4-[(8aS)-6-oxo-octahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pf-04531083
Pf-04531083 has been investigated for the treatment of Pain and Chronic Pain.
Investigational
Matched Iupac: … N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-1-methyl-1H-pyrazole-5-carboxamide …
D-Myo-Inositol-1,4-Bisphosphate
Experimental
C-1027 Aromatized chromophore
Experimental
Matched Iupac: … }-22-hydroxy-14-(7-methoxy-2-methylidene-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-5-carbonyloxy)-17-oxo-2,16 ... (3R,4R,14R,19S)-23-chloro-4-{[(2S,3R,4R,5S)-5-(dimethylamino)-3,4-dihydroxy-6,6-dimethyloxan-2-yl]oxy ... -dioxapentacyclo[18.2.2.1^{9,13}.0^{3,10}.0^{4,8}]pentacosa-1(22),5,7,9,11,13(25),20,23-octaen-19-aminium …
BI-836826
Investigational
Adenosine-5'-[Beta, Gamma-Methylene]Tetraphosphate
Experimental
Matched Name: … Adenosine-5'-[Beta, Gamma-Methylene]Tetraphosphate …
Matched Iupac: … {[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl) …
Matched Iupac: … {[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl) …
4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one
Experimental
Matched Name: … 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one …
Matched Iupac: … 4-amino-7,7-dimethyl-5,6,7,8-tetrahydroquinazolin-5-one …
Matched Iupac: … 4-amino-7,7-dimethyl-5,6,7,8-tetrahydroquinazolin-5-one …
PF-03635659
Pf03635659 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bromochlorosalicylanilide
Experimental
Matched Iupac: … 5-bromo-N-(4-chlorophenyl)-2-hydroxybenzamide …
Flufenoxuron
Flufenoxuron is under investigation in clinical trial NCT00922870 (Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock).
Investigational
Matched Iupac: … 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}-3-(2,6-difluorobenzoyl)urea …
Displaying drugs 11551 - 11575 of 13528 in total