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Displaying drugs 11601 - 11625 of 13528 in total
COVID19 s-vax loaded autologous dendritic cell vaccine
Dendritic cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the presence of specific cytokines and growth factors. These cells are then loaded with antigens produced by a virus or tumor cell and administered as a vaccine.
Dendritic Cells (DCs) are showing potential as natural adjuvants...
Investigational
Matched Description: … The rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can …
Donanemab
Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody targeted against an epitope at the N-terminal of a specific type of amyloid beta (Aβ) - pyroglutamate Aβ - which is found only in the brain amyloid plaques associated with Alzheimer's Disease (AD). It works by inducing microglial-mediated clearance of existing Aβ...
Investigational
Matched Description: … [A232234,L32719]
In March 2021, Eli Lilly announced an expanded trial, named TRAILBLAZER-ALZ 2, which …
Testosterone succinate
Experimental
Matched Iupac: … 9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Polyhexamethyleneguanidine
Investigational
Evorpacept
evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Matched Synonyms: … containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 …
3,4-Epoxybutyl-Alpha-D-Glucopyranoside
Experimental
Matched Iupac: … (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(2S)-oxiran-2-yl]ethoxy}oxane-3,4,5-triol …
4-(Acetylamino)-3-Guanidinobenzoic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-Guanidinobenzoic Acid …
Matched Iupac: … 3-[(diaminomethyl)amino]-4-acetamidobenzoic acid …
Matched Iupac: … 3-[(diaminomethyl)amino]-4-acetamidobenzoic acid …
D-leucyl-N-(3-chlorobenzyl)-L-prolinamide
Experimental
Matched Name: … D-leucyl-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-4-methylpentanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-4-methylpentanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Myristic acid
Experimental
Matched Synonyms: … N-tetradecan-1-oic acid ... 1-tridecanecarboxylic acid …
N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide
Experimental
Matched Name: … N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide …
Matched Iupac: … 2-(carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-carboxypropanamido)-3-phenylpropanamido]-2-(pentylcarbamoyl)ethyl …
Matched Iupac: … 2-(carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-carboxypropanamido)-3-phenylpropanamido]-2-(pentylcarbamoyl)ethyl …
PG-701
Hydroxytriptolide has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Matched Iupac: … (1S,2S,4S,5S,7R,8R,9S,11S,13R)-8,13-dihydroxy-1-methyl-7-(propan-2-yl)-3,6,10,16-tetraoxaheptacyclo[11.7.0.0 …
Afuresertib
Afuresertib has been used in trials studying the treatment of Cancer and Neoplasms, Haematologic.
Investigational
Matched Iupac: … N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene ... -2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tandospirone
Tandospirone has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Iupac: … (1R,2S,6R,7S)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-4-azatricyclo[5.2.1.0²,⁶]decane-3,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
L-Cycloserine
Investigational
Matched Synonyms: … (s)-4-amino-3-isoxazolidinone …
Matched Iupac: … (4S)-4-amino-1,2-oxazolidin-3-one …
Matched Iupac: … (4S)-4-amino-1,2-oxazolidin-3-one …
Vanzacaftor
Investigational
Matched Iupac: … (14S)-8-[3-(2-{dispiro[2.0.2^{4}.1^{3}]heptan-7-yl}ethoxy)-1H-pyrazol-1-yl]-12,12-dimethyl-2lambda6-thia ... -3,9,11,18,23-pentaazatetracyclo[17.3.1.1^{11,14}.0^{5,10}]tetracosa-1(22),5,7,9,19(23),20-hexaene-2,2,4 …
Inodiftagene vixteplasmid
Inodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed non-protein coding gene).
Investigational
RI 624
RI 624 is a novel humanized monoclonal antibody that blocks nerve growth factor (NGF), a key mediator of acute and chronic pain. RI 624 is being developed by Rinat and is currently in Phase I clinical trials.
Investigational
Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine
Experimental
Matched Name: … Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine …
Matched Iupac: … (2S)-2-[(2R)-2-{[(2R,3R,4R,5S,6R)-2-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl ... )-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy …
Matched Iupac: … (2S)-2-[(2R)-2-{[(2R,3R,4R,5S,6R)-2-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl ... )-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy …
Prajmaline
Experimental
Matched Iupac: … dihydroxy-8-methyl-15-propyl-8,15-diazahexacyclo[14.2.1.0^{1,9}.0^{2,7}.0^{10,15}.0^{12,17}]nonadeca-2( …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Baicalein
Baicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ⅡA Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of Improve Other Aspects of Healthy Adult With Influenza Fever).
Investigational
Matched Iupac: … 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Antithrombin gamma
Antithrombin gamma is under investigation in clinical trial NCT04182373 (KW-3357 Study in Patients With Early Onset Severe Preeclampsia).
Investigational
[HYDROXY(3-PHENYLPROPYL)AMINO]METHANOL
Experimental
Matched Name: … [HYDROXY(3-PHENYLPROPYL)AMINO]METHANOL …
Matched Iupac: … [N-hydroxy-N-(3-phenylpropyl)amino]methanol …
Matched Iupac: … [N-hydroxy-N-(3-phenylpropyl)amino]methanol …
Leupeptin
Investigational
Matched Synonyms: … L-leucinamide, n-acetyl-l-leucyl-n-((1s)-4-((aminoiminomethyl)amino)-1-formylbutyl)- ... L-leucinamide, n-acetyl-l-leucyl-n-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (s)- …
Matched Iupac: … (2S)-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}-3-methylbutyl]-2-acetamido-4-methylpentanamide …
Matched Iupac: … (2S)-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}-3-methylbutyl]-2-acetamido-4-methylpentanamide …
Metelimumab
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … Human anti-transforming growth factor beta 1 monoclonal antibody ... Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4- …
Matched Description: … Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1. …
Matched Description: … Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1. …
Displaying drugs 11601 - 11625 of 13528 in total