Displaying drugs 11626 - 11650 of 13353 in total
Alaproclate
Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity observed in animal studies. Alaproclate has also been found to act as a non-competitive NMDA receptor antagonist although without discriminative...
Experimental
Matched Iupac: … 1-(4-chlorophenyl)-2-methylpropan-2-yl 2-aminopropanoate …
Tenitramine
Experimental
Matched Iupac: … 2-[(2-{bis[2-(nitrooxy)ethyl]amino}ethyl)[2-(nitrooxy)ethyl]amino]ethyl nitrate …
Aminodi(Ethyloxy)Ethylaminocarbonylbenzenesulfonamide
Experimental
Matched Iupac: … N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-4-sulfamoylbenzamide …
Naproxen etemesil
Naproxen etemesil has been used in trials studying the treatment of Osteoarthritis.
Investigational
Matched Iupac: … 2-methanesulfonylethyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate …
Trofosfamide
Trofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
Investigational
Matched Iupac: … 2-[bis(2-chloroethyl)amino]-3-(2-chloroethyl)-1,3,2lambda5-oxazaphosphinan-2-one …
Cephalothin Group
Cephalothin group is a solid. This compound belongs to the 1,3-thiazines. These are organic compounds containing 1,3-thiazine, a six-member ring with a nitrogen and a sulfur atom in ring positions 1 and 3 respectively, as well as two double bonds. This substance is known to target beta-lactamase Toho-1 and D-alanyl-D-alanine...
Experimental
Matched Iupac: … (2R)-5-(2-methoxy-2-oxoethyl)-2-[(1R)-2-oxo-1-[2-(thiophen-2-yl)acetamido]ethyl]-3,6-dihydro-2H-1,3-thiazine …
[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER
Experimental
Matched Iupac: … ethyl (2S)-2-[(2S)-2-[(2R)-3-(hydroxycarbamoyl)-2-(2-methylpropyl)propanamido]-4-methylpentanamido]propanoate …
BIO-11006
BIO-11006 is under investigation in clinical trial NCT03202394 (Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS).
Investigational
Matched Iupac: … (2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2 ... -(2-acetamidoacetamido)propanamido]butanamido]-3-phenylpropanamido]-3-hydroxypropanamido]hexanamido]- …
Arverapamil
Investigational
Matched Iupac: … (2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile …
Rhenium (186-Re) obisbemeda
Investigational
Matched Iupac: … (2-{[2-(diethylamino)ethyl](2-sulfanidylethyl)amino}ethyl)sulfanide; (2-{[2-(diethylamino)ethyl](2-sulfanylethyl …
Etofibrate
Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations.
Experimental
Matched Iupac: … 2-(pyridine-3-carbonyloxy)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate …
Ibuprofen piconol
Investigational
Matched Iupac: … (pyridin-2-yl)methyl 2-[4-(2-methylpropyl)phenyl]propanoate …
Deferitazole
Deferitazole is an iron chelator. It has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment, Impaired Renal Function, Transfusional Iron Overload, and Iron Overload Due to Repeated Red Blood Cell Transfusions.
Investigational
Matched Iupac: … (4S)-2-(2-hydroxy-3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}phenyl)-4-methyl-4,5-dihydro-1,3-thiazole-4- …
Ipamorelin
Ipamorelin has been investigated for the treatment of Ileus.
Investigational
Matched Iupac: … (2S)-6-amino-2-[(2R)-2-[(2R)-2-[(2S)-2-(2-amino-2-methylpropanamido)-3-(1H-imidazol-4-yl)propanamido] ... -3-(naphthalen-2-yl)propanamido]-3-phenylpropanamido]hexanamide …
N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide
Experimental
Matched Iupac: … 2-(carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-carboxypropanamido)-3-phenylpropanamido]-2-(pentylcarbamoyl)ethyl …
PX-478
PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma. PX-478 was effective in models of both non-small cell lung cancer
and small cell lung cancer that express HIF-1 alpha.
Investigational
Matched Iupac: … N-{4-[(2S)-2-amino-2-carboxyethyl]phenyl}-2-chloro-N-(2-chloroethyl)ethanamine oxide dihydrochloride …
Azoxystrobin
Azoxystrobin is a methoxyacrylate analog and a strobilurin fungicide.
Experimental
Matched Iupac: … methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoate …
Chinese cinnamon
Experimental
Tiletamine
This drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt form, exists as odorless white crystals.
Vet approved
Matched Iupac: … 2-(ethylamino)-2-(thiophen-2-yl)cyclohexan-1-one …
Matched Salts cas: … 14176-50-2 …
Matched Salts cas: … 14176-50-2 …
Bucillamine
Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.
Investigational
Matched Iupac: … (2R)-2-(2-methyl-2-sulfanylpropanamido)-3-sulfanylpropanoic acid …
Displaying drugs 11626 - 11650 of 13353 in total