This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Carbromal
- DrugBank Accession Number
- DB13817
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Carbromal (DB13817)
- Weight
- Average: 237.097
Monoisotopic: 236.016041 - Chemical Formula
- C7H13BrN2O2
- Synonyms
- Carbromal
- Carbromalum
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your software1,2-Benzodiazepine The risk or severity of CNS depression can be increased when 1,2-Benzodiazepine is combined with Carbromal. Acetazolamide The risk or severity of CNS depression can be increased when Acetazolamide is combined with Carbromal. Acetophenazine The risk or severity of CNS depression can be increased when Acetophenazine is combined with Carbromal. Agomelatine The risk or severity of CNS depression can be increased when Agomelatine is combined with Carbromal. Alfentanil The risk or severity of CNS depression can be increased when Alfentanil is combined with Carbromal. - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- International/Other Brands
- Adalin
Categories
- ATC Codes
- N05CM04 — Carbromal
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as n-acyl ureas. These are compounds containing an urea bearing a N-acyl group.
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Organic carbonic acids and derivatives
- Sub Class
- Ureas
- Direct Parent
- N-acyl ureas
- Alternative Parents
- N-acyl amines / Dicarboximides / Organopnictogen compounds / Organonitrogen compounds / Organobromides / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds / Alkyl bromides
- Substituents
- Aliphatic acyclic compound / Alkyl bromide / Alkyl halide / Carbonyl group / Carboxylic acid derivative / Dicarboximide / Hydrocarbon derivative / N-acyl urea / N-acyl-amine / Organic nitrogen compound
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0Y299JY9V3
- CAS number
- 77-65-6
- InChI Key
- OPNPQXLQERQBBV-UHFFFAOYSA-N
- InChI
- InChI=1S/C7H13BrN2O2/c1-3-7(8,4-2)5(11)10-6(9)12/h3-4H2,1-2H3,(H3,9,10,11,12)
- IUPAC Name
- (2-bromo-2-ethylbutanoyl)urea
- SMILES
- CCC(Br)(CC)C(=O)NC(N)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 6243
- 2067
- ChEBI
- 134961
- ChEMBL
- CHEMBL1697828
- ZINC
- ZINC000000001093
- Wikipedia
- Carbromal
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.976 mg/mL ALOGPS logP 1.57 ALOGPS logP 1.39 Chemaxon logS -2.4 ALOGPS pKa (Strongest Acidic) 10.91 Chemaxon pKa (Strongest Basic) -7.5 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 72.19 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 48.7 m3·mol-1 Chemaxon Polarizability 19.68 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 143.3775035 predictedDarkChem Lite v0.1.0 [M-H]- 137.44948 predictedDeepCCS 1.0 (2019) [M+H]+ 143.6741035 predictedDarkChem Lite v0.1.0 [M+H]+ 140.58116 predictedDeepCCS 1.0 (2019) [M+Na]+ 143.2258035 predictedDarkChem Lite v0.1.0 [M+Na]+ 149.6165 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:49 / Updated at February 21, 2021 18:54