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Displaying drugs 11901 - 11925 of 14366 in total

Avenanthramides

Experimental

11-Deoxy-Beta-Rhodomycin

Experimental
Matched Iupac: … (7R,8R,10S)-10-{[(2R,4S,5S,6S)-4-(dimethylamino)-5-{[(2S,4S,5R,6S)-4-hydroxy-6-methyl-5-{[(2R,6R)-6-methyl ... -5-oxooxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-8-ethyl-1,7,8,11-tetrahydroxy-5,7,8,9,10,12 …

XMMME-001-DTPA 111 Indium

Investigational

Nabiximols

Nabiximols (tradename Sativex®) is a whole plant extract from the Cannabis species Cannabis sativa L. that has been purified into the active components CBD (cannabidiol) and THC (delta-9-tetrahydrocannabinol). For trademark purposes, purified CBD is branded as Nabidiolex®, while THC is purified as the product Tetrabinex®. Sativex® is available in a...
Investigational
Matched Iupac: … (prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol ... (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol; 2-[(1R,6R)-3-methyl-6- …
Matched Description: … (CB1R) and Cannabinoid-2 (CB2R) receptors. ... Sativex® is available in a 1:1 formulation of THC:CBD as an oro-mucosal pump spray used for treatment ... 1 formulation with CBD from purified plant extract as [DB14011]. …

Indanazoline

Experimental
Matched Iupac: … N-(2,3-dihydro-1H-inden-4-yl)-4,5-dihydro-1H-imidazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dirloctocogene samoparvovec

Investigational

N-Pyridoxyl-Threonine-5-Monophosphate

Experimental
Matched Name: … N-Pyridoxyl-Threonine-5-Monophosphate …
Matched Iupac: … 3-hydroxy-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]butanoic acid …

Grapiprant

Grapiprant, also known as AT-001 and CJ-023, is a drug from the piprant class. These molecules were derived from acylsulfonamide and are characterized to be a novel series of para-N-acylaminomethylbenzoic acid known to be prostaglandin receptor antagonists. This type of molecules is currently in development for veterinary patients. This class...
Investigational
Vet approved
Matched Iupac: … 3-[2-(4-{2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl}phenyl)ethyl]-1-(4-methylbenzenesulfonyl) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Plitidepsin

Aplidine is a peptide found in tunicates which shows promise in shrinking tumors in pancreatic, stomach, bladder, and prostate cancers. The specific marine organism is Aplidium albicans. Aplidine is also of interest as a potential treatment for some leukemias.
Investigational
Matched Iupac: … [2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-4-methyl-2-{N-methyl-1-[(2S)-1-(2-oxopropanoyl ... (2R)-N-[(3S,6R,7S,10R,11S,15S,17S,20S,25aS)-10-[(2S)-butan-2-yl]-11-hydroxy-3-[(4-methoxyphenyl)methyl ... ]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,8,13,16,18,21-heptaoxo-15-(propan-2-yl)-docosahydro-1H-pyrrolo ... )pyrrolidin-2-yl]formamido}pentanamide …

Camostat

Camostat mesylate, or FOY-305, is a synthetic serine protease inhibitor.[A193842,A193848] It was first described in the literature in 1981, as part of research on the inhibition of skin tumors in mice. Camostat mesylate inhibits cholecystokinin, pro-inflammatory cytokines, and serine proteases, leading to it being investigated for multiple indications including the...
Experimental
Matched Iupac: … 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate …

Anise oil

Experimental

Repinotan

Repinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective properties.
Investigational
Matched Iupac: … 2-[4-({[(2R)-3,4-dihydro-2H-1-benzopyran-2-yl]methyl}amino)butyl]-2,3-dihydro-1lambda6,2-benzothiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

S-Methyl Thiocysteine Group

Experimental
Matched Name: … S-Methyl Thiocysteine Group …
Matched Iupac: … (2R)-2-amino-3-(methyldisulfanyl)propanoic acid …

Ethyl piperidinoacetylaminobenzoate

Experimental
Matched Iupac: … ethyl 4-[2-(piperidin-1-yl)acetamido]benzoate …

10-decarboxymethylaclacinomycin A

Experimental
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-(dimethylamino)-5-{[(2R,4S,5R,6S)-4-hydroxy-6-methyl-5-{[(2R,6R)-6-methyl ... -5-oxooxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-8-ethyl-1,8,11-trihydroxy-5,7,8,9,10,12-hexahydrotetracene …

3-(Mercaptomethylene)Pyridine

Experimental
Matched Name: … 3-(Mercaptomethylene)Pyridine …
Matched Iupac: … (pyridin-3-yl)methanethiol …

Tanespimycin

Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90). It is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia.
Investigational
Matched Iupac: … en-1-yl)amino]-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18-hexaen-9-yl]oxy}methanimidic acid ... ,9S,10E,12S,13R,14S,16R)-3,13-dihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-20,22-dioxo-19-[(prop-2- …

Esflurbiprofen

Esflurbiprofen is under investigation in clinical trial NCT03434197 (Safety and Efficacy of SFPP in Knee Osteoarthritis).
Investigational
Matched Synonyms: … Flurbiprofen, (s)- …
Matched Iupac: … (2S)-2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …

cis-Vaccenic acid

Experimental

Pilsicainide

Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
Investigational
Matched Iupac: … N-(2,6-dimethylphenyl)-2-(hexahydro-1H-pyrrolizin-7a-yl)acetamide …
Matched Salts cas: … 88069-49-2 …

Efungumab

Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
Investigational

Tosatoxumab

Tosatoxumab is a fully-human monoclonal antibody (IgG1λ) targeting the Staphylococcus aureus alpha-toxin or the S. aureus alpha-hemolysin[A191829, L31568, L31573] and thereby preserving human immune cells by protecting against destruction of host cells mediated by the toxin.
Investigational
Matched Description: … is a fully-human monoclonal antibody (IgG1λ) targeting the Staphylococcus aureus alpha-toxin or the S. …

beta-Alanine

beta-Alanine is an amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
Experimental
Matched Synonyms: … 3-aminopropanoic acid ... 3-aminopropionic acid …
Matched Iupac: … 3-aminopropanoic acid …

Myristoyl-Coa

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-[(2-{[2-(tetradecanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]propoxy]phosphoryl}oxy)phosphoryl]oxy ... }methyl)oxolan-3-yl]oxy}phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tocladesine

Tocladesine has been used in trials studying the treatment of Colorectal Cancer and Multiple Myeloma and Plasma Cell Neoplasm.
Investigational
Matched Iupac: … (6-amino-8-chloro-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 11901 - 11925 of 14366 in total