Displaying drugs 12101 - 12125 of 12254 in total
Phosmet
Phosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals, and vines to control aphids, suckers, mites, and fruit flies.
Vet approved
Matched Description: … Phosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Platycodon grandiflorus root
Platycodon grandiflorus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Platycodon grandiflorus root is a plant/plant extract used in some OTC (over-the-counter) products. …
Edotreotide yttrium Y-90
Investigational
Recifercept
Investigational
Boldenone undecylenate
Illicit
Vet approved
Matched Iupac: … 3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
MDX-018
MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. Other possible indications include chronic obstructive pulmonary disease (COPD)...
Investigational
Matched Description: … Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. ... MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin- ... HuMax-Inflam was also effective in reducing disease activity in palmoplantar pustulosis patients in a …
Human umbilical cord blood mononuclear cell-conditioned medium
Transplantation with human umbilical cord blood mononuclear cells (HUCBC) has demonstrated promising results in various disease states. While some of the positive results are credited to HUCBCs’ differentiation potential, the growth factors and cytokines these cells secrete are also implicated. When HUCBCs secrete growth factors and anti-inflammatory cytokines, they are...
Investigational
Matched Description: … While some of the positive results are credited to HUCBCs’ differentiation potential, the growth factors …
IMM101
IMM-101 is a heat-inactivated immune-activating mycobacterial product. It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma [PMID: 21930686; PMID: 30107850; PMID: 27599039]. Studies with IMM-101 showed the vaccine’s ability to stimulate cancer patients’ immune systems to help...
Investigational
Matched Description: … As of July 2020, researchers from the Ottawa Hospital and Queen’s University, in partnership with the ... IMM-101 is a heat-inactivated immune-activating mycobacterial product. ... Canadian Cancer Society-funded Canadian Cancer Trials Group (CCTG), are conducting a trial in over 1500 …
Sugemalimab
Sugemalimab is a fully human, full-length IgG4 monoclonal anti-PD-L1 antibody discovered by CStone Pharmaceuticals and being investigated against relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) in adult patients and T-cell lymphoma.[L32868, L32873] It has been granted the Breakthrough Therapy Designation by the FDA to treat R/R ENKTL...
Investigational
Matched Description: … [L32868] Sugemalimab is under investigation in clinical trial NCT03802591 (A Study of CS1001 in Subjects ... Sugemalimab is a fully human, full-length IgG4 monoclonal anti-PD-L1 antibody discovered by CStone Pharmaceuticals …
HY10275
HY10275 is a novel compound specifically designed to modulate two key neurobiological mechanisms that interfere with the sleeping process. HY10275 is highly selective for histamine H1 and serotonin 5HT2a, two chemical receptors that are known to impact the ability to fall asleep and stay asleep. HY10275 was rationally designed to...
Investigational
Matched Description: … HY10275 is a novel compound specifically designed to modulate two key neurobiological mechanisms that ... This dual-acting receptor activity and the lack of affinity for undesired off- target receptors are thought …
Covax-19™
Covax-19™, a protein-based vaccine, was developed through partnership between APC and Vaxine. It uses an insect-cell-produced recombinant SARS-CoV-2 spike protein and Vaxine’s adjuvant, Advax-SM. This adjuvant is designed to circumvent high fevers, fatigue, and aches experienced with other vaccines using more traditional adjuvants. Covax-19™ was tested in animal studies, and...
Investigational
Matched Description: … Covax-19™, a protein-based vaccine, was developed through partnership between APC and Vaxine. ... As of June 2020, the vaccine is in Phase 1 trials to evaluate safety and immune responses (NCT04428073 …
PBI-1402
PBI-1402 is a small molecule synthetic compound with oral
Bioavailability. The compound activates neutrophils, enhancing their survival and activation with comparable efficacy to GM-CSF, G-CSF and EPO, which are currently used to treat anemia. However, it has been shown that when co-administered with these compounds, effects are additive, making PBI-1402...
Investigational
Matched Description: … making PBI-1402 an excellent candidate for combination therapy and asserting its independent mechanism of ... PBI-1402 has a dual therapeutic action; as a chemoprotectant and hematopoietic progenitor stimulator. ... PBI-1402 is a small molecule synthetic compound with oral
Bioavailability. …
Cosfroviximab
Investigational
Bevasiranib
Bevasiranib is a small interfering RNA (siRNA) targeting vascular endothelial growth factor A (VEGF-A).
Investigational
Matched Description: … Bevasiranib is a small interfering RNA (siRNA) targeting vascular endothelial growth factor A (VEGF-A …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Trametes versicolor fruiting body
Trametes versicolor fruiting body is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Trametes versicolor fruiting body is a plant/plant extract used in some OTC (over-the-counter) products …
COVID-19 convalescent plasma
COVID-19 convalescent plasma is plasma collected from patients who have acquired and subsequently recovered from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2. This investigational COVID-19 treatment is currently available through three main pathways: use in registered clinical trials, use through the expanded access COVID-19 protocol (21 CFR...
Investigational
Matched Description: … [L14333]
Although there are no formal clinical trial results for the safety or efficacy of COVID-19 …
NasoVAX
NasoVAX contains replication-deficient adenovirus vectors in suspension. It is a vaccine administered through a nasal spray that expresses influenza hemagglutinin in nasal epithelial cells . Created by Altimmune, Inc., NasoVAX is currently being developed for seasonal and pandemic use as it can activate humoral and cellular immune responses. The compound...
Investigational
Matched Description: … As of June 2020, NasoVAX is being evaluated in a Phase 2 clinical trial for safety and effectivness in ... It is a vaccine administered through a nasal spray that expresses influenza hemagglutinin in nasal epithelial ... compound has already shown to be tolerated with no adverse effects or fever in healthy individuals with a …
Batimastat
Experimental
PF-07304814
PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro), which is used by viruses like SARS-CoV-2 to assemble and multiply . Once administered through intravenous infusion, the compound is cleaved into PF-00835231 to exert its anti-viral effects . PF-07304814, developed by Pfizer, was first identified during the...
Investigational
Matched Description: … PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro) ... Phase 1b studies are also exploring the safety and tolerability of PF-07304814 in COVID-19 patients who …
Iluzanebart
Investigational
Displaying drugs 12101 - 12125 of 12254 in total