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Displaying drugs 1201 - 1225 of 1284 in total
Experimental
Matched Name: … BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE …
Matched Iupac: … methyl-5-[4-({[(2s,5s)-2-carboxy-2-methyl-1,3-dioxan-5-yl]oxy}carbonyl)piperazine-1-carbonyloxy]-1,3-dioxane
5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
Experimental
Matched Synonyms: … Thymidine 5'-phosphoric acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine …
Matched Iupac: … (2S)-2-[(2S)-3-{[(1R)-1-aminoethyl](hydroxy)phosphoryl}-2-({[1,1'-biphenyl]-4-yl}methyl)propanamido]propanoic …
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Erythropoietin (recombinant human) ... Erythropoietin (human, recombinant) …
Matched Description: … the human erythropoietin gene has been introduced. ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. ... The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ERITROPOYETINA HUMANA RECOMBINANTE ... ERITROPOYETINA HUMANA RECOMBINANTE 2000 UI ... ERITROPOYETINA HUMANA RECOMBINANTE 2000UI/ML …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human platetet glycoprotein vi) fab fragment (humanized monoclonal act017 .gamma …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Description: … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … enriched cell fraction that contains CD34+ cells transduced with retroviral vector that encodes for the human
Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … GLUCAGON ANALOG CONJUGATED WITH HUMAN IMMUNOGLOBULIN G4 FRAGMENT ... IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)- …
Experimental
Matched Name: … BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE
Investigational
Matched Synonyms: … -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain ... cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human
Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Synonyms: … Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107 …
Matched Description: … GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their ... Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ ... Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).
Investigational
Matched Synonyms: … allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that …
Matched Description: … CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy …
Begelomab is a murine monoclonal antibody against CD26.
Experimental
Investigational
Matched Synonyms: … COMPLEXING PROTEIN 2, ADCP2, TP103, T CELL ACTIVATION ANTIGEN CD26, CD26)), MUS MUSCULUS MONOCLONAL ANTIBODY
Matched Description: … Begelomab is a murine monoclonal antibody against CD26. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Investigational
Matched Synonyms: … An autologous chimeric antigen receptor (CAR) T-cell therapy engineered to express an antibody-derived …
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Human recombinant bone morphogenetic protein 7 …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte …
Matched Description: … It is being investigated for cancers and autoimmune disorders. ... Ocaratuzumab is a humanized monoclonal antibody directed against CD20. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/e7 Synthetic Long Peptide (SLP) Vaccine Component D-3082-L …
Matched Description: … D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Experimental
Matched Name: … Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane …
Matched Iupac: … 5-({[2-({[(2-carboxy-2-methyl-1,3-dioxan-5-yl)oxy]carbonyl}amino)ethyl]carbamoyl}oxy)-2-methyl-1,3-dioxane
Experimental
Matched Name: … (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE …
Investigational
Matched Synonyms: … Cancer testis antigen ny-eso-1 (recombinant human) ... Glycyl-l-prolyl-human cancer/testis antigen 1 (autoimmunogenic cancer/testis antigen ny-eso-1, l antigen …
Experimental
Matched Name: … cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
Experimental
Matched Name: … {4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID …
Cinpanemab is under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease).
Investigational
Matched Synonyms: … -synuclein) (human monoclonal biib054 .gamma.1-chain), disulfide with human monoclonal biib054 .kappa ... Immunoglobulin g1, anti-(human .alpha. …
Matched Description: … under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and
AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … mediated, genetically modified autologous cell therapy intended for the stable provision of functional human
Matched Description: … genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human
Displaying drugs 1201 - 1225 of 1284 in total