Displaying drugs 1201 - 1225 of 1781 in total
ssCART-19 cells
ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).
Investigational
Matched Synonyms: … against interleukin-6 (IL-6) (also termed ssCART-19 cells) ... autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) …
Matched Name: … ssCART-19 cells …
Matched Description: … ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a …
Matched Name: … ssCART-19 cells …
Matched Description: … ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a …
Autologous Human Peripheral Blood Lymphocytes
Investigational
Matched Name: … Autologous Human Peripheral Blood Lymphocytes …
Heparan-N-sulfatase (human, recombinant)
Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis type IIIA.
Investigational
Matched Synonyms: … Recombinant human heparan-N-sulfatase …
Matched Name: … Heparan-N-sulfatase (human, recombinant) …
Matched Description: … Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis …
Matched Name: … Heparan-N-sulfatase (human, recombinant) …
Matched Description: … Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis …
Lovotibeglogene autotemcel
Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified β-globin gene. Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (βA-T87Q-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding capacity as wild type hemoglobin. Additionally,...
Approved
Investigational
Matched Synonyms: … Lovo-cel …
Matched Description: … Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced ... disease (SCD) in patients ages 12 and older who have a history of vaso-occlusive events. ... gene therapies for the treatment of SCD in patients 12 years and older to be approved by the FDA. …
Matched Categories: … Autologous Cultured Cell ... Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Matched Description: … Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced ... disease (SCD) in patients ages 12 and older who have a history of vaso-occlusive events. ... gene therapies for the treatment of SCD in patients 12 years and older to be approved by the FDA. …
Matched Categories: … Autologous Cultured Cell ... Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with silicic …
Matched Description: … It is one of the 5 most prevalent skin diseases in the world and the third-most common viral skin infection ... A262960] Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral ... skin discoloration, and fear and anxiety in the pediatric population. …
Matched Categories: … Silicon Compounds …
Matched Description: … It is one of the 5 most prevalent skin diseases in the world and the third-most common viral skin infection ... A262960] Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral ... skin discoloration, and fear and anxiety in the pediatric population. …
Matched Categories: … Silicon Compounds …
CM-101
Investigational
Matched Synonyms: … Monoclonal antibody targeting CCL24 ... Monoclonal antibody targeting eotaxin-2 …
Binetrakin
Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others.
Investigational
Matched Synonyms: … Interleukin 4 human ... Interleukin 4 (human) ... Interleukin-4 (human; nonglycosylated) …
Matched Description: … treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
CYP-001
CYP-001 is a mesenchymoangioblast (MCA)-derived mesenchymal stem cell (MSC) therapy that originates from the mesoderm. When activated with fibroblast growth factor-2 (FGF-2), MCAs create colonies with specific phenotypes. These cells are then able to differentiate into bone, cartilage, and adipose tissue.
The MCA-derived MSCs can be obtained from induced pluripotent...
Investigational
Matched Synonyms: … Mesenchymoangioblast-derived mesenchymal stem cells …
Matched Description: … These cells are then able to differentiate into bone, cartilage, and adipose tissue. ... The MCA-derived MSCs can be obtained from induced pluripotent stem cells (iPSCs) and then expanded in ... These cells are used to treat chronic allergic airway disease and fibrosis, among other pathologies. …
Matched Description: … These cells are then able to differentiate into bone, cartilage, and adipose tissue. ... The MCA-derived MSCs can be obtained from induced pluripotent stem cells (iPSCs) and then expanded in ... These cells are used to treat chronic allergic airway disease and fibrosis, among other pathologies. …
Efmarodocokin alfa
Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Investigational
Matched Synonyms: … >P(158)), CH2(N67>G(227)))-(147-377), DIMER (156-156':159-159')-BISDISULFIDE, PRODUCED IN CHO CELLS, ... HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10 ... INTERLEUKIN 22 (HUMAN (MATURE)) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (SYNTHETIC HUMAN .GAMMA.4-CHAIN …
Matched Description: … Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and …
Matched Description: … Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and …
GDX012
Investigational
Matched Synonyms: … Allogeneic Vδ1+ γδ T cells ... Allogeneic enriched variable delta 1 gamma delta T-cells …
Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is a vaccine for intramuscular injection used in the prevention of invasive disease caused by Haemophilus influenzae type b. H. influenzae is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis. The vaccine contains the Haemophilus...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate …
Matched Name: … Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Description: … The toxoid antigen is purified and toxin-inactivated. ... *H. influenzae* is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis ... Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is …
Matched Name: … Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Description: … The toxoid antigen is purified and toxin-inactivated. ... *H. influenzae* is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis ... Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) ... Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Denenicokin
Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
Matched Synonyms: … Recombinant human IL-21 ... L-METHIONYL(HUMAN INTERLEUKIN-21) ... RECOMBINANT HUMAN INTERLEUKIN 21 …
Cholecystokinin
Cholecystokinin ( also known as CCK or CCK-PZ) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum (the first portion of the small intestine) and leads...
Approved
Investigational
Matched Synonyms: … Human CCK-33 ... Human cholecystokinin-33 …
Matched Description: … in the duodenum (the first portion of the small intestine) and leads to the release of bile and digestive ... Cholecystokinin, previously called _pancreozymin_, is synthesized and secreted by enteroendocrine cells ... cell growth, energy production, gene expression and protein synthesis, processes that have profound …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cholagogues and Choleretics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … in the duodenum (the first portion of the small intestine) and leads to the release of bile and digestive ... Cholecystokinin, previously called _pancreozymin_, is synthesized and secreted by enteroendocrine cells ... cell growth, energy production, gene expression and protein synthesis, processes that have profound …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cholagogues and Choleretics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin (synthetic human) ... Human Thrombin (recombinant, glycosylated) …
Matched Description: … viral clearance. ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … viral clearance. ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Lenograstim
Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Synonyms: … G-CSF (CHO cell derived) ... Granulocyte colony stimulating factor 3 (CHO cell derived) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hematopoietic Cell Growth Factors ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hematopoietic Cell Growth Factors ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Clervonafusp alfa
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, cell-penetrating humanized fab fragment targeting the equilibrative nucleoside ... transporter 2 (ent2), fused with a human lysosomal .alpha. ... -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain …
Human botulinum neurotoxin A/B immune globulin
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism. …
Matched Categories: … Human Immunoglobulin G …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism. …
Matched Categories: … Human Immunoglobulin G …
Dazukibart
Investigational
Matched Synonyms: … Recombinant humanized monoclonal antibody (immunoglobulin gamma-1 with kappa light chains, IgG1kappa) ... β) (human-Mus musculus monoclonal PF-06823859 γ1-chain), disulfide with human-Mus musculus monoclonal ... directed against human soluble cytokine interferon beta. …
Cefacetrile
A derivative of 7-aminocephalosporanic acid.
Experimental
Vet approved
Matched International brands: … Celtol …
Matched Products: … CELOR ENTRAVENÖZ AMPUL 2G, 1 ADET ... CELOR ENTRAVENÖZ AMPUL 2G, 5 ADET …
Matched Products: … CELOR ENTRAVENÖZ AMPUL 2G, 1 ADET ... CELOR ENTRAVENÖZ AMPUL 2G, 5 ADET …
GL-2045
Investigational
Matched Synonyms: … Recombinant human IgG1 Fc multimer ... Recombinant Multimerized Human IgG1 Fc …
Recifercept
Investigational
Matched Synonyms: … isoform (337-400>del, 414-784>del)-sfgfr3), produced in chinese hamster ovary (cho) cells, glycoform ... Recombinant human fibroblast growth factor receptor 3 ... Fibroblast growth factor receptor 3 (recombinant human soluble isoform ta-46) …
Displaying drugs 1201 - 1225 of 1781 in total