Displaying drugs 1226 - 1250 of 1297 in total
WU-CART-007
WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Investigational
Matched Synonyms: … genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
Matched Description: … genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
Matched Description: … genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
AVE9633
AVE9633 is an anti-CD33 monoclonal antibody-DM4 conjugate.
Investigational
Matched Synonyms: … huMy9-6-DM4 …
Matched Description: … AVE9633 is an anti-CD33 monoclonal antibody-DM4 conjugate. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … AVE9633 is an anti-CD33 monoclonal antibody-DM4 conjugate. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Belzupacap Sarotalocan
Investigational
Matched Synonyms: … Human papillomavirus virus-like particles conjugated with ir700 dye au-011 …
L-3972-T
L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/E7 Synthetic Long Peptide (SLP) Vaccine Component L-3972-T …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Cerliponase alfa
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Spesolimab
Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain) …
Matched Description: … works by inhibiting the inflammatory signaling pathway of IL-36,[L43090] which is often overexpressed and ... Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved in December ... It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … works by inhibiting the inflammatory signaling pathway of IL-36,[L43090] which is often overexpressed and ... Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved in December ... It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Iluzanebart
Investigational
Matched Synonyms: … on myeloid cells 2) (human monoclonal VGL101 γ1-chain), disulfide with human monoclonal VGL101 κ-chain ... Immunoglobulin G1 [296-cysteine,301-glycine,306-cysteine], anti-(human triggering receptor expressed …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Erythropoietin (recombinant human) ... Erythropoietin (human, recombinant) …
Matched Description: … the human erythropoietin gene has been introduced. ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. ... The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ERITROPOYETINA HUMANA RECOMBINANTE ... ERITROPOYETINA HUMANA RECOMBINANTE 2000 UI ... ERITROPOYETINA HUMANA RECOMBINANTE 2000UI/ML …
Matched Description: … the human erythropoietin gene has been introduced. ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. ... The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ERITROPOYETINA HUMANA RECOMBINANTE ... ERITROPOYETINA HUMANA RECOMBINANTE 2000 UI ... ERITROPOYETINA HUMANA RECOMBINANTE 2000UI/ML …
Oxfendazole
Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Investigational
Vet approved
Matched Synonyms: … Fenbendazole sulfoxide …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. ... Oxfendazole is a sulfoxide metabolite of fenbendazole. …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. ... Oxfendazole is a sulfoxide metabolite of fenbendazole. …
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Olenasufligene relduparvovec
Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying …
Matched Description: … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene. …
Matched Description: … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene. …
Glenzocimab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human platetet glycoprotein vi) fab fragment (humanized monoclonal act017 .gamma …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
RP-A501
RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is being investigated for Danon disease.
Investigational
Matched Synonyms: … Adeno-associated virus serotype 9 vector containing the human lysosome-associated membrane glycoprotein …
Matched Description: … product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human …
Matched Description: … product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human …
Clervonafusp alfa
Investigational
Matched Synonyms: … -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain ... cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human …
Strimvelis
Investigational
Matched Synonyms: … enriched cell fraction that contains CD34+ cells transduced with retroviral vector that encodes for the human …
Regramostim
Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Synonyms: … Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107 …
Matched Description: … GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their ... Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ ... Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their ... Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ ... Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
CYNK-101
CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).
Investigational
Matched Synonyms: … allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that …
Matched Description: … CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy …
Matched Description: … CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy …
Inolimomab
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Description: … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Efocipegtrutide
Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … GLUCAGON ANALOG CONJUGATED WITH HUMAN IMMUNOGLOBULIN G4 FRAGMENT ... IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)- …
Alglucosidase alfa
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Eptotermin alfa
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Human recombinant bone morphogenetic protein 7 …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Musculo-Skeletal System ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Musculo-Skeletal System ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Ocaratuzumab
Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte …
Matched Description: … It is being investigated for cancers and autoimmune disorders. ... Ocaratuzumab is a humanized monoclonal antibody directed against CD20. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It is being investigated for cancers and autoimmune disorders. ... Ocaratuzumab is a humanized monoclonal antibody directed against CD20. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
D-3082-L
D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/e7 Synthetic Long Peptide (SLP) Vaccine Component D-3082-L …
Matched Description: … D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Matched Description: … D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
3,6-Anhydro-2-(hydrogen sulfate)-alpha-D-galactopyranose
Experimental
Matched Name: … 3,6-Anhydro-2-(hydrogen sulfate)-alpha-D-galactopyranose …
Baloramotide
Investigational
Matched Synonyms: … Cancer testis antigen ny-eso-1 (recombinant human) ... Glycyl-l-prolyl-human cancer/testis antigen 1 (autoimmunogenic cancer/testis antigen ny-eso-1, l antigen …
Displaying drugs 1226 - 1250 of 1297 in total