Displaying drugs 12676 - 12700 of 13448 in total
(4s)-5-Fluoro-L-Leucine
Experimental
Matched Iupac: … (2S,4S)-2-amino-5-fluoro-4-methylpentanoic acid …
Dazoxiben
Experimental
Matched Iupac: … 4-[2-(1H-imidazol-1-yl)ethoxy]benzoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
4-Deoxy-D-Glucuronic Acid
Experimental
Matched Iupac: … (2S,4S,5R,6R)-4,5,6-trihydroxyoxane-2-carboxylic acid …
Alanosine
An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
Investigational
Matched Iupac: … (2S)-2-amino-3-[hydroxy(nitroso)amino]propanoic acid …
4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID
Experimental
Matched Iupac: … 4-({4-[(1E)-2-phenylethenyl]phenyl}carbamoyl)butanoic acid …
Spaglumic acid
Spaglumic acid is the β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl)-l-glutamic acid). In eye drops, spaglumic acid is either a magnesium or sodium salt of N-Acetyl-l-aspartylglutamate. Spaglumic acid is a mast cell stabilizer. Thus it is used in allergic conditions such as allergic conjunctivitis. Specifically spaglumic acid is approved...
Experimental
Matched Iupac: … (2S)-2-[(3S)-3-carboxy-3-acetamidopropanamido]pentanedioic acid …
Glafenine
An anthranilic acid derivative with analgesic properties used for the relief of all types of pain. Glafenine is withdrawn from the American market.
Withdrawn
Matched Iupac: … 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate …
Imidafenacin
Imidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder. It is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical.
Investigational
Matched Iupac: … 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Chlorproethazine
Experimental
Matched Iupac: … [3-(2-chloro-10H-phenothiazin-10-yl)propyl]diethylamine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Azintamide
Investigational
Matched Iupac: … 2-[(6-chloropyridazin-3-yl)sulfanyl]-N,N-diethylacetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cavosonstat
Cavosonstat is under investigation in clinical trial NCT02589236 (Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation).
Investigational
Matched Iupac: … 3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid …
Motexafin lutetium
Motexafin lutetium (MLu) is a second-generation photosensitizer for photodynamic therapy (PDT) of cancer. It belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. Motexafin lutetium is a pentadentate aromatic metallotexaphyrin with photosensitizing properties.
Investigational
Matched Iupac: … lutetium(3+) 4,5-diethyl-9,24-bis(3-hydroxypropyl)-16,17-bis({2-[2-(2-methoxyethoxy)ethoxy]ethoxy})-10,23 ... -dimethyl-13,20,25,26,27-pentaazapentacyclo[20.2.1.1^{3,6}.1^{8,11}.0^{14,19}]heptacosa-1,3,5,7,9,11( …
Matched Salts cas: … 156436-90-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 156436-90-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Motexafin gadolinium
Motexafin gadolinium is studied in the treatment of cancer by Pharmacyclics. It may make tumor cells more sensitive to radiation therapy, improve tumor images using magnetic resonance imaging (MRI), and kill cancer cells. It belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin.
Investigational
Matched Iupac: … gadolinium(3+) 4,5-diethyl-9,24-bis(3-hydroxypropyl)-16,17-bis({2-[2-(2-methoxyethoxy)ethoxy]ethoxy}) ... -10,23-dimethyl-13,20,25,26,27-pentaazapentacyclo[20.2.1.1^{3,6}.1^{8,11}.0^{14,19}]heptacosa-1(25),2,4,6,8 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sisomicin
Sisomicin has been used in trials studying the treatment of Pyoderma.
Investigational
Matched Iupac: … (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran ... -2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol …
Sparsomycin
An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
Experimental
Matched Iupac: … (2E)-N-[(2S)-1-hydroxy-3-[(R)-(methylsulfanyl)methanesulfinyl]propan-2-yl]-3-(6-methyl-2,4-dioxo-1,2,3,4 ... -tetrahydropyrimidin-5-yl)prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Casopitant
Investigational
Matched Iupac: … (2R,4S)-4-(4-acetylpiperazin-1-yl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl ... )-N-methylpiperidine-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Neurokinin-1 Receptor Antagonists …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Neurokinin-1 Receptor Antagonists …
Brivanib
Brivanib is under investigation for the treatment of HepatoCellular Carcinoma. Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC).
Investigational
Matched Iupac: … (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan ... -2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dodecyl-Coa
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(dodecanoylsulfanyl)ethyl]carbamoyl} ... )-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl …
beta-Mannobiose
Experimental
Matched Iupac: … (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy …
N-[Isoleucinyl]-N'-[adenosyl]-diaminosufone
Experimental
Matched Iupac: … )-3-methylpentanamide ... (2S,3S)-2-amino-N-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}sulfamoyl …
Thiocellobiose
Experimental
Matched Iupac: … (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]sulfanyl …
Thiodigalactoside
Thiodigalactoside is a solid. This compound belongs to the dihexoses. These are disaccharides containing two hexose carbohydrates. This medication is known to target galectin-1, heat-labile enterotoxin b chain, neurocan core protein, and lactose permease.
Experimental
Matched Iupac: … (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl …
Matched Description: … This medication is known to target galectin-1, heat-labile enterotoxin b chain, neurocan core protein …
Matched Description: … This medication is known to target galectin-1, heat-labile enterotoxin b chain, neurocan core protein …
Abivertinib
Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. In binding to and inhibiting EGFR and BTK receptors,...
Investigational
Matched Iupac: … N-{3-[(2-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl ... }prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 12676 - 12700 of 13448 in total